Protein Alignment Toll-4 and CG18249

DIOPT Version :10

• Sequence 1: NP_523519.2
• Gene: Toll-4 / 34235
• FlyBaseID: FBgn0032095
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_001163549.1
• Gene: CG18249 / 40964
• FlyBaseID: FBgn0037553
• Length: 559
• Species: Drosophila melanogaster
• Alignment Length: 487
• Identity: 102/487 - (20%)
• Similarity: 168/487 - (34%)
• Gaps: 182/487 - (37%)

  Fly   304 LRSSTLQSSLTYCIMK-----VDNMVDLKS------------FEKFTNLEIIEVSQYKGFKNFTA 351
            ||:..:::..||.|.|     |:|:..|:.            |.....|||:::||     ||.
  Fly    81 LRTLVIRNCATYHISKESLRPVENLTSLQMQGTSLGVLRDQIFNAVPRLEILQLSQ-----NFI- 139

  Fly   352 FICEPYKSHCKFTLGINEVACPLKCNCSYNRDKSQLEIDCWQKNLTTIPSLPVPKKGSSALVFQS 416
                 :..|.....|:                 |:|.:                      |..|.
  Fly   140 -----HTVHVAAFQGL-----------------SKLRL----------------------LGLQG 160

  Fly   417 NLLAELPDNSLEGYHNLKSLDVSYNQLTSL--SVSQLPESLHYLDIRHNKITTLSPQVVEYLYSV 479
            |.:||:..::|:....|..||:|.|:||:|  ::....:.|..|.:..|.:..|.|.|:..|.::
  Fly   161 NAIAEILSSTLDPLMELVHLDLSRNELTTLPQNIFAKNKKLQTLLLNGNPLRILMPDVLGSLPNL 225

  Fly   480 NVFNQYGNKWSIYCDEYHLQEFFWYKAKLLRIKTSKFQTIMEYIELSSKGSFVEN-FFVQNIDQL 543
            .:.           |..|..|.     :::.:..:..|.::  :|.||..|.|.| .|::
  Fly   226 RLL-----------DLGHAAEL-----EVMTLNLTNVQNLV--LEGSSLSSLVINGGFIK----- 267

  Fly   544 YLEANEDEIIDAFGPSDKYFNLKLMEALNHAIWLFSGEFDEII---LHH--LNSPCPYRCSCCFE 603
             |:|..:|                   |||   |..|....:|   ||.  ||..
  Fly   268 -LQAGNNE-------------------LNH---LQVGNKSSVIEMDLHGNLLNGN---------- 299

  Fly   604 WHTGEFLINCRNLSLDIYPRLPNSIPYKTTLYLDRNEIRKL---------TNTESLVVAGHASIH 659
             .|...|....||.               .|.|.:|.|..|         :.|:.|::.  .|:.
  Fly   300 -DTAALLRGMWNLQ---------------RLDLSKNRIEALPQHGSGLDASGTQELLIL--PSLK 346

  Fly   660 KLHMSQNLLRELPLH--LLPENITYLDVRNNLLKYLDDGVIAFL--------------------- 701
            .|:::.|.|..||..  :|...::|||:.:||:..||..::..|
  Fly   347 FLNLANNQLVRLPPESPILSSRLSYLDLSHNLMLTLDVAILRSLSVLKGLYVEGNRLNTINYQKL 411

  Fly   702 -EYRENITKIELSGNPWECNCKAKAFLSFLRR 732
             |...:::::.|..|||......|.||.|..|
  Fly   412 HEEHPDLSELGLHDNPWSSGLYRKMFLYFTDR 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-4	NP_523519.2	LRR	210..>470	CDD:443914	39/184 (21%)
		leucine-rich repeat	264..287	CDD:275380
		leucine-rich repeat	288..308	CDD:275380	2/3 (67%)
		leucine-rich repeat	309..334	CDD:275380	8/41 (20%)
		leucine-rich repeat	335..386	CDD:275380	9/50 (18%)
		PRK15370	<381..>482	CDD:185268	23/102 (23%)
		leucine-rich repeat	388..408	CDD:275380	0/19 (0%)
		leucine-rich repeat	412..432	CDD:275378	6/19 (32%)
		LRR	<416..591	CDD:443914	41/182 (23%)
		leucine-rich repeat	433..454	CDD:275378	8/22 (36%)
		leucine-rich repeat	455..478	CDD:275378	7/22 (32%)
		leucine-rich repeat	479..490	CDD:275378	0/10 (0%)
		leucine-rich repeat	632..657	CDD:275378	7/33 (21%)
		leucine-rich repeat	658..679	CDD:275378	6/22 (27%)
		leucine-rich repeat	680..706	CDD:275378	9/47 (19%)
		PCC	684..>771	CDD:188093	16/71 (23%)
		leucine-rich repeat	707..719	CDD:275378	4/11 (36%)
		leucine-rich repeat	771..791	CDD:275380
		PRK15370	<793..>877	CDD:185268
		leucine-rich repeat	793..815	CDD:275378
		leucine-rich repeat	816..835	CDD:275378
		leucine-rich repeat	836..859	CDD:275378
		TIR	974..1110	CDD:214587
CG18249	NP_001163549.1	leucine-rich repeat	57..80	CDD:275380
		LRR	105..433	CDD:443914	89/451 (20%)
		leucine-rich repeat	105..128	CDD:275380	2/22 (9%)
		leucine-rich repeat	129..152	CDD:275380	9/50 (18%)
		leucine-rich repeat	153..176	CDD:275380	7/44 (16%)
		leucine-rich repeat	177..200	CDD:275380	8/22 (36%)
		leucine-rich repeat	201..224	CDD:275380	7/22 (32%)
		leucine-rich repeat	225..258	CDD:275380	7/50 (14%)
		leucine-rich repeat	259..310	CDD:275380	18/89 (20%)
		leucine-rich repeat	311..344	CDD:275380	8/49 (16%)
		leucine-rich repeat	345..368	CDD:275380	6/22 (27%)
		leucine-rich repeat	369..390	CDD:275380	7/20 (35%)
		leucine-rich repeat	393..417	CDD:275380	1/23 (4%)