Protein Alignment Toll-4 and trn

DIOPT Version :10

• Sequence 1: NP_523519.2
• Gene: Toll-4 / 34235
• FlyBaseID: FBgn0032095
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_001261796.1
• Gene: trn / 39491
• FlyBaseID: FBgn0010452
• Length: 751
• Species: Drosophila melanogaster
• Alignment Length: 430
• Identity: 87/430 - (20%)
• Similarity: 152/430 - (35%)
• Gaps: 129/430 - (30%)

  Fly   364 TLGINEVA----CPLKCNCSYNRDKSQLEIDCWQKNLTTIPSLPVPKKGSSALVFQSNLLAELPD 424
            ::|:...|    ||..|.|    |.:.|.:.|.:..|..:|....|  ....||.:||.:..: |
  Fly    18 SIGVEPAAGLANCPPGCQC----DDNTLVVQCGEGQLDVLPIALNP--SIQRLVIKSNKIKTI-D 75

  Fly   425 NSLEGYHNLKSLDVSYNQLTSLSVSQ----LPESLHYLDIRHNKITTLSPQVVEYLYSVNVFNQY 485
            :|::.|..|..||:|.|.|  :::.|    ..:.|..:.:.||||..:|.:....|.:|.|.|..
  Fly    76 SSIQFYAELTFLDLSSNHL--MTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVTVLNLR 138

  Fly   486 GNKWS---------------------------------------IYCDEY--------------- 496
            ||:.|                                       :|.|:.
  Fly   139 GNQISELHQGTFTPLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVIFQAMP 203

  Fly   497 HLQEFFWYKAKLLRIKTSKFQTIMEYIELSSKGSFVENFF------VQNIDQLYLEANEDEIIDA 555
            .|.|.|.....|..|:...||.:.....|..||:.:.|..      :|.:..|.|..|..:.|.:
  Fly   204 SLAELFLGMNTLQSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPS 268

  Fly   556 FGPSDKYFNLKLMEALNHAIWLFSGEFDEIILHHLNSPCPYRCSCCFEWHTGEFLINCRNLSLDI 620
            .|.|    .|..:|.|:    |...:|:.|                   ..|.|:
  Fly   269 VGLS----KLVRLEQLS----LGQNDFEVI-------------------SEGAFM---------- 296

  Fly   621 YPRLPNSIPYKTTLYLDRNEIRKLTNTESLVVAGHASIHKLHMSQN-LLRELPLHLLP--ENITY 682
                    ..|....|:.|...:|....:...:.:.::..|::|.| :|.|:....|.  ..:.:
  Fly   297 --------GLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEVQEGALSGLSQLKH 353

  Fly   683 LDVRNNLLKYLDDGVIAFLEYRENITKIELSGNPWECNCK 722
            :.::.|.|..|.:|:..:    :::..::||.||..|:|:
  Fly   354 VVLKANALTSLAEGLFPW----KDLQTLDLSENPLSCDCR 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-4	NP_523519.2	LRR	210..>470	CDD:443914	31/113 (27%)
		leucine-rich repeat	264..287	CDD:275380
		leucine-rich repeat	288..308	CDD:275380
		leucine-rich repeat	309..334	CDD:275380
		leucine-rich repeat	335..386	CDD:275380	7/25 (28%)
		PRK15370	<381..>482	CDD:185268	28/104 (27%)
		leucine-rich repeat	388..408	CDD:275380	4/19 (21%)
		leucine-rich repeat	412..432	CDD:275378	7/19 (37%)
		LRR	<416..591	CDD:443914	51/238 (21%)
		leucine-rich repeat	433..454	CDD:275378	7/24 (29%)
		leucine-rich repeat	455..478	CDD:275378	7/22 (32%)
		leucine-rich repeat	479..490	CDD:275378	5/10 (50%)
		leucine-rich repeat	632..657	CDD:275378	3/24 (13%)
		leucine-rich repeat	658..679	CDD:275378	6/23 (26%)
		leucine-rich repeat	680..706	CDD:275378	4/25 (16%)
		PCC	684..>771	CDD:188093	10/39 (26%)
		leucine-rich repeat	707..719	CDD:275378	4/11 (36%)
		leucine-rich repeat	771..791	CDD:275380
		PRK15370	<793..>877	CDD:185268
		leucine-rich repeat	793..815	CDD:275378
		leucine-rich repeat	816..835	CDD:275378
		leucine-rich repeat	836..859	CDD:275378
		TIR	974..1110	CDD:214587
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	6/18 (33%)
		LRR	82..406	CDD:443914	68/359 (19%)
		leucine-rich repeat	84..107	CDD:275380	7/24 (29%)
		leucine-rich repeat	108..131	CDD:275380	7/22 (32%)
		leucine-rich repeat	132..155	CDD:275380	6/22 (27%)
		leucine-rich repeat	156..179	CDD:275380	0/22 (0%)
		leucine-rich repeat	180..204	CDD:275380	2/23 (9%)
		leucine-rich repeat	205..228	CDD:275380	7/22 (32%)
		leucine-rich repeat	229..252	CDD:275380	4/22 (18%)
		leucine-rich repeat	253..276	CDD:275380	7/26 (27%)
		leucine-rich repeat	277..300	CDD:275380	7/63 (11%)
		leucine-rich repeat	301..322	CDD:275380	3/20 (15%)
		leucine-rich repeat	326..350	CDD:275380	6/23 (26%)
		leucine-rich repeat	351..373	CDD:275380	4/25 (16%)
		LRRCT	382..434	CDD:214507	4/8 (50%)