DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-zeta and ntm

DIOPT Version :9

Sequence 1:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	XP_021334871.1	Gene:	ntm / 678534	ZFINID:	ZDB-GENE-060421-6020	Length:	380	Species:	Danio rerio

Alignment Length:	389	Identity:	101/389 - (25%)
Similarity:	177/389 - (45%)	Gaps:	45/389 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 VAGSGTGSTVVGSNGVIVAGGGANVPTSNLNIVVEEPEFTEYIENVTVPAGRNVKLGCSVKNLGS 141
            |.|......|:|...:.:...|..|.:..     |.....:.::|:|:..|..:.|.||..:..:
Zfish     5 VCGCWRRCVVMGLRLLFLLPAGLPVRSQG-----ESQSDNKQMDNITIRQGETLFLSCSQGDFVT 64

  Fly   142 YKVAWMHFEQSAILTVHNHVITRNPRIS-VTHDKHDRHRTWYLHINNVHEEDRGRYMCQINTVT- 204
            : .||::  :|:||.......:.:||:| ||..:.:    :.:.|.:|...|.|:|:|.:.|.:
Zfish    65 H-TAWLN--RSSILYAGEDKWSVDPRVSLVTLSQEE----FTIKIEDVDVTDEGQYICAVQTSSR 122

  Fly   205 AKTQFGYLNVVVPPNIDDSLSSSDVIVREGANISLRCRASGSPRPIIKWKRDDNSRIAINKNHIV 269
            .:|...::.|.|||.|.:  .|.|::|.||:|::|.|.|:|.|.|.|.|:....|..:::.
Zfish   123 PRTTSVHIIVQVPPKIVN--LSRDLVVNEGSNVTLMCLANGKPEPAIVWRMKSPSDDSLSS---- 181

  Fly   270 NEWEGDTLEITRISRLDMGAYLCIASNGVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIE 334
               :.:.|:|..|||...|.|.|.|:|.: ...::.::::|::.|.:..... ||...|....::
Zfish   182 ---DSEVLDIPFISRYRAGVYECTAANDI-AVDTQTVELTVNYAPSVSDGRD-VGVTLGQRGVLQ 241

  Fly   335 CFTEAHPTSLNYWTRGEGPIIHDSHKYKVEATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKNPR 399
            |..:|.|.:...|.|.:..|.:.....::||...|      .:||..|||..|.|.|.|||.|..
Zfish   242 CEADAVPEADFEWYRDDRRIFNGLDGIEIEAAGAL------SRLTFFNVSEADYGNYTCVAINKL 300

  Fly   400 GETDGIIRLYVSYPPT--------TASSGIYSTDTHWGENGINNNYAYGGPDSTRSIYAQDKNT 455
            |..:....||....||        |:.|.:..|.:...:..:.|: .:.||.:     .||.|:
Zfish   301 GSANTSFVLYEIIEPTSSTLLQVETSPSVLEMTSSDLEQTPLQND-LWEGPGA-----VQDGNS 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	25/97 (26%)
		Ig	130..200	CDD:143165	19/70 (27%)
		I-set	226..310	CDD:254352	25/83 (30%)
		IGc2	233..298	CDD:197706	22/64 (34%)
		Ig	313..410	CDD:299845	27/96 (28%)
		IG_like	325..410	CDD:214653	24/84 (29%)
ntm	XP_021334871.1	Ig	44..132	CDD:325142	24/94 (26%)
		Ig_3	135..205	CDD:316449	27/78 (35%)
		I-set	228..309	CDD:333254	25/87 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576310
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I4644
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		otm26286
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.900