DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-zeta and Ntm

DIOPT Version :10

Sequence 1:NP_723441.2 Gene:DIP-zeta / 34231 FlyBaseID:FBgn0051708 Length:532 Species:Drosophila melanogaster
Sequence 2:NP_001418383.1 Gene:Ntm / 50864 RGDID:620958 Length:367 Species:Rattus norvegicus


Alignment Length:329 Identity:104/329 - (31%)
Similarity:155/329 - (47%) Gaps:37/329 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    91 GVIVAGGGANVPTSNLNIVVEEPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAIL 155
            ||.|..|.|..|.:              ::||||..|.:..|.|::.|..: :|||::  :|.||
  Rat    28 GVPVRSGDATFPKA--------------MDNVTVRQGESATLRCTIDNRVT-RVAWLN--RSTIL 75

  Fly   156 TVHNHVITRNPRISVTHDKHDRHRTWYLHINNVHEEDRGRYMCQINTVT-AKTQFGYLNVVVPPN 219
            ...|.....:||:.:..:...::.   :.|.||...|.|.|.|.:.|.. .||...:|.|.|.|.
  Rat    76 YAGNDKWCLDPRVVLLSNTQTQYS---IEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPK 137

  Fly   220 IDDSLSSSDVIVREGANISLRCRASGSPRPIIKWKRDDNSRIAINKNHIVNEWEGDTLEITRISR 284
            |.:  .|||:.:.||.||||.|.|:|.|.|.:.|:.       |:...:....|.:.|||..|:|
  Rat   138 IVE--ISSDISINEGNNISLTCIATGRPEPTVTWRH-------ISPKAVGFVSEDEYLEIQGITR 193

  Fly   285 LDMGAYLCIASNGVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTR 349
            ...|.|.|.|||.|...|.:|:||:|::|| .:...:..|.|.|...|::|...|.|::...|.:
  Rat   194 EQSGEYECSASNDVAAPVVRRVKVTVNYPP-YISEAKGTGVPVGQKGTLQCEASAVPSAEFQWFK 257

  Fly   350 GEGPIIHDSHKYKVEATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKNPRGETDGIIRLYVSYPP 414
            .:..::......|||....|      .:||..|||..|.|.|.|||.|..|.|:..|.|:....|
  Rat   258 DDKRLVEGKKGVKVENRPFL------SRLTFFNVSEHDYGNYTCVASNKLGHTNASIMLFELNEP 316

  Fly   415 TTAS 418
            |:::
  Rat   317 TSST 320

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-zetaNP_723441.2 IG_like 120..216 CDD:214653 29/96 (30%)
Ig strand B 130..134 CDD:409405 1/3 (33%)
Ig strand C 143..147 CDD:409405 2/3 (67%)
Ig strand E 178..185 CDD:409405 0/6 (0%)
IgI_1_MuSK 218..310 CDD:409562 35/91 (38%)
Ig strand A 218..221 CDD:409562 1/2 (50%)
Ig strand A' 226..231 CDD:409562 3/4 (75%)
Ig strand B 237..244 CDD:409562 4/6 (67%)
Ig strand C 250..255 CDD:409562 1/4 (25%)
Ig strand C' 257..259 CDD:409562 0/1 (0%)
Ig strand D 267..270 CDD:409562 0/2 (0%)
Ig strand E 275..281 CDD:409562 3/5 (60%)
Ig strand F 288..295 CDD:409562 3/6 (50%)
Ig strand G 302..310 CDD:409562 4/7 (57%)
IG_like 325..410 CDD:214653 27/84 (32%)
Ig strand B 331..335 CDD:143207 1/3 (33%)
Ig strand C 344..348 CDD:143207 0/3 (0%)
Ig strand E 376..380 CDD:143207 1/3 (33%)
Ig strand F 390..395 CDD:143207 2/4 (50%)
Ig strand G 403..406 CDD:143207 0/2 (0%)
NtmNP_001418383.1 Ig 44..132 CDD:472250 28/93 (30%)
Ig strand B 53..57 CDD:409382 1/3 (33%)
Ig strand C 65..69 CDD:409382 2/3 (67%)
Ig strand E 98..102 CDD:409382 0/6 (0%)
Ig strand F 112..117 CDD:409382 2/4 (50%)
Ig strand G 125..128 CDD:409382 1/2 (50%)
Ig_3 136..205 CDD:464046 28/77 (36%)
Ig 223..307 CDD:472250 27/90 (30%)
Ig strand B 239..243 CDD:409408 1/3 (33%)
Ig strand C 252..256 CDD:409408 0/3 (0%)
Ig strand E 278..282 CDD:409408 1/3 (33%)
Ig strand F 292..297 CDD:409408 2/4 (50%)

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