Protein Alignment DIP-zeta and LSAMP

DIOPT Version :10

• Sequence 1: NP_723441.2
• Gene: DIP-zeta / 34231
• FlyBaseID: FBgn0051708
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_001305844.1
• Gene: LSAMP / 4045
• HGNCID: 6705
• Length: 361
• Species: Homo sapiens
• Alignment Length: 355
• Identity: 110/355 - (30%)
• Similarity: 163/355 - (45%)
• Gaps: 47/355 - (13%)

  Fly   101 VPTSNLNIVVEEPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAILTVHNHVITRN 165
            :||   .:.|...:|....:|:||..|....|.|.|::..| ||||::  :|.|:...:...:.:
Human    23 LPT---GLPVRSVDFNRGTDNITVRQGDTAILRCVVEDKNS-KVAWLN--RSGIIFAGHDKWSLD 81

  Fly   166 PRISVTHDKHDRHRTWY-LHINNVHEEDRGRYMCQINTV-TAKTQFGYLNVVVPPNIDDSLSSSD 228
            ||:.:    ..||...| |.|..|...|.|.|.|.:.|. ..||...||.|.|||.|  |..|||
Human    82 PRVEL----EKRHSLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKI--SNISSD 140

  Fly   229 VIVREGANISLRCRASGSPRPIIKWKRDDNSRIAINKNHIV---NEWEGDT--LEITRISRLDMG 288
            |.|.||:|::|.|.|:|.|.|:|.|:            |:.   .|:||:.  |||..|:|...|
Human   141 VTVNEGSNVTLVCMANGRPEPVITWR------------HLTPTGREFEGEEEYLEILGITREQSG 193

  Fly   289 AYLCIASNGVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRGEGP 353
            .|.|.|:|.|.....|::||:|::|| .:...:...|..|...:::|...|.|.....|.| :..
Human   194 KYECKAANEVSSADVKQVKVTVNYPP-TITESKSNEATTGRQASLKCEASAVPAPDFEWYR-DDT 256

  Fly   354 IIHDSHKYKVEATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKNPRGETDGIIRLYVSYPPTTAS 418
            .|:.::..::::|.|      ...||:.||:....|.|.|||.|..|.|:..:.|:....||...
Human   257 RINSANGLEIKSTEG------QSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFKRVLPTIPH 315

  Fly   419 SGIYSTDTHWGENGINNNYAYGGPDSTRSI 448
            .        ..|.|...::...||.|.|.|
Human   316 P--------IQEIGTTVHFKQKGPGSVRGI 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	32/97 (33%)
		Ig strand B	130..134	CDD:409405	1/3 (33%)
		Ig strand C	143..147	CDD:409405	3/3 (100%)
		Ig strand E	178..185	CDD:409405	3/7 (43%)
		IgI_1_MuSK	218..310	CDD:409562	37/96 (39%)
		Ig strand A	218..221	CDD:409562	1/2 (50%)
		Ig strand A'	226..231	CDD:409562	4/4 (100%)
		Ig strand B	237..244	CDD:409562	2/6 (33%)
		Ig strand C	250..255	CDD:409562	2/4 (50%)
		Ig strand C'	257..259	CDD:409562	0/1 (0%)
		Ig strand D	267..270	CDD:409562	1/5 (20%)
		Ig strand E	275..281	CDD:409562	3/7 (43%)
		Ig strand F	288..295	CDD:409562	3/6 (50%)
		Ig strand G	302..310	CDD:409562	3/7 (43%)
		IG_like	325..410	CDD:214653	23/84 (27%)
		Ig strand B	331..335	CDD:143207	0/3 (0%)
		Ig strand C	344..348	CDD:143207	0/3 (0%)
		Ig strand E	376..380	CDD:143207	1/3 (33%)
		Ig strand F	390..395	CDD:143207	2/4 (50%)
		Ig strand G	403..406	CDD:143207	0/2 (0%)
LSAMP	NP_001305844.1	Ig	38..128	CDD:472250	31/96 (32%)
		Ig strand B	49..53	CDD:409353	1/3 (33%)
		Ig strand C	61..65	CDD:409353	3/3 (100%)
		Ig strand E	94..98	CDD:409353	2/3 (67%)
		Ig strand F	108..113	CDD:409353	2/4 (50%)
		Ig strand G	121..124	CDD:409353	1/2 (50%)
		Ig_3	131..201	CDD:464046	33/83 (40%)
		Ig_3	218..294	CDD:464046	21/83 (25%)