Protein Alignment DIP-zeta and IGLON5

DIOPT Version :10

• Sequence 1: NP_723441.2
• Gene: DIP-zeta / 34231
• FlyBaseID: FBgn0051708
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_001094842.1
• Gene: IGLON5 / 402665
• HGNCID: 34550
• Length: 336
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 93/326 - (28%)
• Similarity: 137/326 - (42%)
• Gaps: 40/326 - (12%)

  Fly    92 VIVAGGGANVPTSNLNIVVEEPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAILT 156
            ::.|...|.:...:..::.:..||....:|.||..|.|..|.|.:....: :|||::  :|.||.
Human    12 LLAAAALAGLAVISRGLLSQSLEFNSPADNYTVCEGDNATLSCFIDEHVT-RVAWLN--RSNILY 73

  Fly   157 VHNHVITRNPRISVTHDKHDRHRTWYLHINNVHEEDRGRYMCQINT--VTAKTQFGYLNVVVPPN 219
            ..|...|.:||:.:..:..:.   :.:.|..|...|.|.|.|...|  ....||. ||.|.||..
Human    74 AGNDRWTSDPRVRLLINTPEE---FSILITEVGLGDEGLYTCSFQTRHQPYTTQV-YLIVHVPAR 134

  Fly   220 IDDSLSSSDVIVREGANISLRCRASGSPRPIIKWK--RDDNSRIAINKNHIVNEWEGDTLEITRI 282
            |.:  .||.|.|.||.|::|.|.|.|.|.|.:.|:  ||..:.            ||:.|||:.|
Human   135 IVN--ISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTS------------EGEILEISDI 185

  Fly   283 SRLDMGAYLCIASNGVPPTV-SKRIKVSVDFPPMLLIPHQLVGAPE--GFNVTIECFTEAHPTSL 344
            .|...|.|.|:..|||.... |:|:.|:|::||.:.   .:..|..  |....:.|...|.|.:.
Human   186 QRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTIT---DVTSARTALGRAALLRCEAMAVPPAD 247

  Fly   345 NYWTRGEGPIIHDSHKYKVEATVGLPAY--KTHMKLTIINVSSGDDGIYKCVAKNPRGETDGIIR 407
            ..|.:       |..........||...  :|...|...|||:...|.|.|.|.|..|.:...:|
Human   248 FQWYK-------DDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMR 305

  Fly   408 L 408
            |
Human   306 L 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	29/97 (30%)
		Ig strand B	130..134	CDD:409405	1/3 (33%)
		Ig strand C	143..147	CDD:409405	2/3 (67%)
		Ig strand E	178..185	CDD:409405	0/6 (0%)
		IgI_1_MuSK	218..310	CDD:409562	33/94 (35%)
		Ig strand A	218..221	CDD:409562	0/2 (0%)
		Ig strand A'	226..231	CDD:409562	3/4 (75%)
		Ig strand B	237..244	CDD:409562	2/6 (33%)
		Ig strand C	250..255	CDD:409562	1/6 (17%)
		Ig strand C'	257..259	CDD:409562	0/1 (0%)
		Ig strand D	267..270	CDD:409562	0/2 (0%)
		Ig strand E	275..281	CDD:409562	3/5 (60%)
		Ig strand F	288..295	CDD:409562	3/6 (50%)
		Ig strand G	302..310	CDD:409562	3/8 (38%)
		IG_like	325..410	CDD:214653	22/88 (25%)
		Ig strand B	331..335	CDD:143207	0/3 (0%)
		Ig strand C	344..348	CDD:143207	0/3 (0%)
		Ig strand E	376..380	CDD:143207	1/3 (33%)
		Ig strand F	390..395	CDD:143207	2/4 (50%)
		Ig strand G	403..406	CDD:143207	0/2 (0%)
IGLON5	NP_001094842.1	Ig strand G	122..125	CDD:409382	1/2 (50%)
		Ig_3	134..199	CDD:464046	27/78 (35%)
		Ig_3	217..295	CDD:464046	20/87 (23%)
		Ig	41..129	CDD:472250	28/94 (30%)
		Ig strand B	50..54	CDD:409382	1/3 (33%)
		Ig strand C	62..66	CDD:409382	2/3 (67%)
		Ig strand E	95..99	CDD:409382	0/3 (0%)
		Ig strand F	109..114	CDD:409382	2/4 (50%)