DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-zeta and robo1

DIOPT Version :10

Sequence 1:NP_723441.2 Gene:DIP-zeta / 34231 FlyBaseID:FBgn0051708 Length:532 Species:Drosophila melanogaster
Sequence 2:NP_476899.1 Gene:robo1 / 37603 FlyBaseID:FBgn0005631 Length:1395 Species:Drosophila melanogaster


Alignment Length:479 Identity:117/479 - (24%)
Similarity:183/479 - (38%) Gaps:107/479 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   108 IVVEEPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTH 172
            ||..:|.|.:..::..:..|:.....|||......||.|...|.:..::          |..:.|
  Fly   250 IVQVKPYFMKEPKDQVMLYGQTATFHCSVGGDPPPKVLWKKEEGNIPVS----------RARILH 304

  Fly   173 DKHDRHRTWYLHINNVHEEDRGRYMCQ----INTVTAKTQFGYLNVVVPPNIDDSLSSSDVIVRE 233
            |:..      |.|:|:...|.|.|:|:    :..::|:..   |.|..|||.....|:..|    
  Fly   305 DEKS------LEISNITPTDEGTYVCEAHNNVGQISARAS---LIVHAPPNFTKRPSNKKV---- 356

  Fly   234 GAN--ISLRCRASGSPRPIIKWKRDDNSRIAI-NKNHIVNEWEGD-TLEITRISRLDMGAYLCIA 294
            |.|  :.|.|.|||:|.|.:.|.::..|.:.. |.:|.......| ||:||.:.:.|.|.|:|.|
  Fly   357 GLNGVVQLPCMASGNPPPSVFWTKEGVSTLMFPNSSHGRQHVAADGTLQITDVRQEDEGYYVCSA 421

  Fly   295 SNGV-PPTVSKRIKV-SVDF--PPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRGEGPII 355
            .:.| ..||...::| |:|.  ||::.|.......|:|...|:.|....:|:....|       .
  Fly   422 FSVVDSSTVRVFLQVSSLDERPPPIIQIGPANQTLPKGSVATLPCRATGNPSPRIKW-------F 479

  Fly   356 HDSHKYKVEATVGLPAYKTHMKLTIINVSS--------GDDGIYKCVAKNPRGETDGIIRLYVSY 412
            ||.|           |.:...:.:||..||        .|.|.|.|.|...||||.....|.|..
  Fly   480 HDGH-----------AVQAGNRYSIIQGSSLRVDDLQLSDSGTYTCTASGERGETSWAATLTVEK 533

  Fly   413 PPTT-----ASSGIY---------------STDTHWGENG---------INNNYAYGGPD-STRS 447
            |.:|     |....|               |....|.::.         |.....|..|| .|..
  Fly   534 PGSTSLHRAADPSTYPAPPGTPKVLNVSRTSISLRWAKSQEKPGAVGPIIGYTVEYFSPDLQTGW 598

  Fly   448 IYAQDKNTRYQSNLNEIGLSEQKSFL-----DKTQNPLLANGNAN-----EADAESNGARGHNPS 502
            |.|..:....|..::  ||:...|::     :.||...:.:|.:|     |||.::..|.    .
  Fly   599 IVAAQRVGDTQVTIS--GLTPGTSYVFLVRAENTQGISVPSGLSNTIKTIEADFDAASAN----D 657

  Fly   503 MAIAWLFVVIATLLLTIRSAVGSS 526
            ::.|...:...::.|...||:.:|
  Fly   658 LSAARTLLTGKSVELIDASAINAS 681

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
DIP-zetaNP_723441.2 IG_like 120..216 CDD:214653 21/99 (21%)
Ig strand B 130..134 CDD:409405 0/3 (0%)
Ig strand C 143..147 CDD:409405 2/3 (67%)
Ig strand E 178..185 CDD:409405 1/6 (17%)
IgI_1_MuSK 218..310 CDD:409562 31/97 (32%)
Ig strand A 218..221 CDD:409562 2/2 (100%)
Ig strand A' 226..231 CDD:409562 1/4 (25%)
Ig strand B 237..244 CDD:409562 2/6 (33%)
Ig strand C 250..255 CDD:409562 1/4 (25%)
Ig strand C' 257..259 CDD:409562 0/1 (0%)
Ig strand D 267..270 CDD:409562 1/2 (50%)
Ig strand E 275..281 CDD:409562 4/6 (67%)
Ig strand F 288..295 CDD:409562 3/6 (50%)
Ig strand G 302..310 CDD:409562 2/8 (25%)
IG_like 325..410 CDD:214653 24/92 (26%)
Ig strand B 331..335 CDD:143207 1/3 (33%)
Ig strand C 344..348 CDD:143207 0/3 (0%)
Ig strand E 376..380 CDD:143207 0/3 (0%)
Ig strand F 390..395 CDD:143207 2/4 (50%)
Ig strand G 403..406 CDD:143207 0/2 (0%)
robo1NP_476899.1 Ig 56..151 CDD:472250
Ig strand B 73..77 CDD:409353
Ig strand C 86..90 CDD:409353
Ig strand E 111..115 CDD:409353
Ig strand F 129..134 CDD:409353
Ig strand G 143..146 CDD:409353