DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-zeta and Nrg

DIOPT Version :10

Sequence 1:NP_723441.2 Gene:DIP-zeta / 34231 FlyBaseID:FBgn0051708 Length:532 Species:Drosophila melanogaster
Sequence 2:NP_001245581.1 Gene:Nrg / 31792 FlyBaseID:FBgn0264975 Length:1309 Species:Drosophila melanogaster


Alignment Length:478 Identity:122/478 - (25%)
Similarity:184/478 - (38%) Gaps:122/478 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    89 SNGVIVAGGGANVPTSNLNIVVEEPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWMH----F 149
            ||||    |.|...:..|| |...|.||:..|..|......|...|....:...|::|:|    .
  Fly   320 SNGV----GNAQSFSIILN-VNSVPYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPI 379

  Fly   150 EQSAILTVHNHVITRNPRISVTHDKHDRHRTWYLHINNVHEEDRGRYMCQINTVTAKTQFG---- 210
            |||          |.|||.:||.:.        :.|.|:.:.|.|.|.|     .|....|    
  Fly   380 EQS----------TPNPRRTVTDNT--------IRIINLVKGDTGNYGC-----NATNSLGYVYK 421

  Fly   211 --YLNV-VVPPNIDDSLSSSDVIVREGANISLRCRASGSPRPIIKWKRDDN----SRIAINKNHI 268
              |||| ..||.|.::.::...:  :|.|::::||.:|||:|::||.|..|    .|..:..|  
  Fly   422 DVYLNVQAEPPTISEAPAAVSTV--DGRNVTIKCRVNGSPKPLVKWLRASNWLTGGRYNVQAN-- 482

  Fly   269 VNEWEGDTLEITRISRLDMGAYLCIASNGVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNV-- 331
                 || |||..::..|.|.|.|.|.|       |..::..|...::....::...|:.:.|  
  Fly   483 -----GD-LEIQDVTFSDAGKYTCYAQN-------KFGEIQADGSLVVKEHTRITQEPQNYEVAA 534

  Fly   332 ----TIECFTEAHPTSL----NYWTRGEGPIIHDSHKYKVEATVGLPAY-KTH-MKLTIINVSSG 386
                |..| .|||..:|    ::|..|:      |..::.:     |.: ||: ..|||......
  Fly   535 GQSATFRC-NEAHDDTLEIEIDWWKDGQ------SIDFEAQ-----PRFVKTNDNSLTIAKTMEL 587

  Fly   387 DDGIYKCVAKNPRGETDGIIRLYVSYPPTTAS-SGIY----STDTHWGENGINN----------N 436
            |.|.|.|||:....|......|.|...|.... :||.    ..:.||.:.|.|.          |
  Fly   588 DSGEYTCVARTRLDEATARANLIVQDVPNAPKLTGITCQADKAEIHWEQQGDNRSPILHYTIQFN 652

  Fly   437 YAYGGPDSTRSIYAQDKNT------------RYQSNL---NEIGLSEQKSFLDK-TQNPLLANGN 485
            .:: .|.|..:.|.:..||            .|...:   |:||.|...:..|. |..|.:...|
  Fly   653 TSF-TPASWDAAYEKVPNTDSSFVVQMSPWANYTFRVIAFNKIGASPPSAHSDSCTTQPDVPFKN 716

  Fly   486 ANEADAESNGARGHNP-SMAIAW 507
            .:....:     |..| ::.|:|
  Fly   717 PDNVVGQ-----GTEPNNLVISW 734

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-zetaNP_723441.2 IG_like 120..216 CDD:214653 28/106 (26%)
Ig strand B 130..134 CDD:409405 1/3 (33%)
Ig strand C 143..147 CDD:409405 1/3 (33%)
Ig strand E 178..185 CDD:409405 0/6 (0%)
IgI_1_MuSK 218..310 CDD:409562 28/95 (29%)
Ig strand A 218..221 CDD:409562 1/2 (50%)
Ig strand A' 226..231 CDD:409562 0/4 (0%)
Ig strand B 237..244 CDD:409562 2/6 (33%)
Ig strand C 250..255 CDD:409562 2/4 (50%)
Ig strand C' 257..259 CDD:409562 1/5 (20%)
Ig strand D 267..270 CDD:409562 0/2 (0%)
Ig strand E 275..281 CDD:409562 4/5 (80%)
Ig strand F 288..295 CDD:409562 3/6 (50%)
Ig strand G 302..310 CDD:409562 1/7 (14%)
IG_like 325..410 CDD:214653 25/96 (26%)
Ig strand B 331..335 CDD:143207 2/9 (22%)
Ig strand C 344..348 CDD:143207 1/7 (14%)
Ig strand E 376..380 CDD:143207 1/3 (33%)
Ig strand F 390..395 CDD:143207 2/4 (50%)
Ig strand G 403..406 CDD:143207 0/2 (0%)
NrgNP_001245581.1 Ig 29..128 CDD:472250
Ig strand B 55..59 CDD:409353
Ig strand C 68..72 CDD:409353
Ig strand E 94..98 CDD:409353
Ig strand F 108..113 CDD:409353
Ig strand G 122..125 CDD:409353
Ig 137..216 CDD:472250
Ig strand B 151..155 CDD:409353
Ig strand C 165..169 CDD:409353
Ig strand E 192..196 CDD:409353
Ig strand F 209..214 CDD:409353
ig 251..332 CDD:395002 6/15 (40%)
Ig strand B 264..268 CDD:409353
Ig strand C 277..281 CDD:409353
Ig strand E 305..309 CDD:409353
Ig strand F 314..319 CDD:409353
Ig strand G 328..331 CDD:409353 0/2 (0%)
IgI_4_hemolin-like 339..427 CDD:409570 29/110 (26%)
Ig strand A 339..342 CDD:409570 1/2 (50%)
Ig strand A' 348..351 CDD:409570 1/2 (50%)
Ig strand B 356..363 CDD:409570 2/6 (33%)
Ig strand C 369..374 CDD:409570 2/4 (50%)
Ig strand C' 377..379 CDD:409570 0/1 (0%)
Ig strand D 387..391 CDD:409570 1/3 (33%)
Ig strand E 393..397 CDD:409570 0/11 (0%)
Ig strand F 406..414 CDD:409570 4/12 (33%)
Ig strand G 417..427 CDD:409570 3/9 (33%)
Ig 446..517 CDD:472250 27/85 (32%)
Ig strand B 449..453 CDD:409358 0/3 (0%)
Ig strand C 462..466 CDD:409358 1/3 (33%)
Ig strand E 483..487 CDD:409358 3/4 (75%)
Ig strand F 497..502 CDD:409358 2/4 (50%)
Ig strand G 510..513 CDD:409358 0/2 (0%)
Ig 521..615 CDD:472250 26/105 (25%)
Ig strand B 538..542 CDD:409353 1/3 (33%)
Ig strand C 553..557 CDD:409353 0/3 (0%)
Ig strand E 577..581 CDD:409353 1/3 (33%)
Ig strand F 591..596 CDD:409353 2/4 (50%)
Ig strand G 604..607 CDD:409353 0/2 (0%)
FN3 613..707 CDD:238020 19/94 (20%)
FN3 683..>1051 CDD:442628 13/57 (23%)
fn3 817..905 CDD:394996
fn3 918..1007 CDD:394996
FN3 1041..1111 CDD:238020
Bravo_FIGEY 1155..>1221 CDD:464016
Blue background indicates that the domain is not in the aligned region.

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