DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-zeta and Igsf9

DIOPT Version :10

Sequence 1:NP_723441.2 Gene:DIP-zeta / 34231 FlyBaseID:FBgn0051708 Length:532 Species:Drosophila melanogaster
Sequence 2:NP_001100667.1 Gene:Igsf9 / 304982 RGDID:1304566 Length:1179 Species:Rattus norvegicus


Alignment Length:335 Identity:84/335 - (25%)
Similarity:141/335 - (42%) Gaps:55/335 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   112 EPEFTEYIENVTVPAGRNVKLGCSVKNLGS----YKVAWMHFEQSAILTVHNHVITRNPRISVTH 172
            :||    :.:|...||.:..|||.:.....    :.:.|:.|  ..:|.:.......:|||...:
  Rat    23 KPE----VVSVVGRAGESAVLGCDLLPPAGRPPLHVIEWLRF--GFLLPIFIQFGLYSPRIDPDY 81

  Fly   173 DKHDRHRTW-YLHINNVHEEDRGRYMCQINTVT--------AKTQFGYLNVVVPPNIDDSLSSSD 228
            ....|.:|. .|.|..:..||:|.|.|::..:.        |...:.:|.|..||...:: ....
  Rat    82 VGRVRLQTGASLQIEGLRVEDQGWYECRVLFLDQHSPEQDFANGSWVHLTVNSPPQFQET-PPLV 145

  Fly   229 VIVREGANISLRCRASGSPRPIIKWK-RDDNSRIAINKNHIVNEWEGDTLEITRISRLDMGAYLC 292
            :.|:|...::|||.|.|||:|.:.|| |..:    :.|.....:....||.|.|:.|...|.|.|
  Rat   146 LEVKELEAVTLRCVALGSPQPYVTWKFRGQD----LGKGQGQVQVRNGTLWIRRVERGSAGDYTC 206

  Fly   293 IASNGVPPTVSKRIKVSVDFPPMLLIP--HQLVGAPEGFNVTIECFTEAHPTSLNY-WTRGEGPI 354
            .||: ...:|:...::.|..||::::|  :..|.|.:  :|::.|..||:|.:|.| |.:....:
  Rat   207 QASS-TEGSVTHTTQLLVLGPPVIVVPPNNNTVNASQ--DVSLACRAEAYPANLTYSWFQDRINV 268

  Fly   355 IHDSH-----KYKVEATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKN----PRGETDGIIRLYV 410
            .|.|.     :..|:.::.|.|           ....|.|.|.||..|    |...:..:..||.
  Rat   269 FHISRLQSRVRILVDGSLWLQA-----------TQPDDAGHYTCVPSNGFPHPPSASAYLTVLYP 322

  Fly   411 S----YPPTT 416
            :    .||.|
  Rat   323 AQVTVMPPET 332

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-zetaNP_723441.2 IG_like 120..216 CDD:214653 24/108 (22%)
Ig strand B 130..134 CDD:409405 1/3 (33%)
Ig strand C 143..147 CDD:409405 0/3 (0%)
Ig strand E 178..185 CDD:409405 2/7 (29%)
IgI_1_MuSK 218..310 CDD:409562 26/92 (28%)
Ig strand A 218..221 CDD:409562 1/2 (50%)
Ig strand A' 226..231 CDD:409562 0/4 (0%)
Ig strand B 237..244 CDD:409562 3/6 (50%)
Ig strand C 250..255 CDD:409562 2/5 (40%)
Ig strand C' 257..259 CDD:409562 0/1 (0%)
Ig strand D 267..270 CDD:409562 0/2 (0%)
Ig strand E 275..281 CDD:409562 3/5 (60%)
Ig strand F 288..295 CDD:409562 3/6 (50%)
Ig strand G 302..310 CDD:409562 1/7 (14%)
IG_like 325..410 CDD:214653 22/94 (23%)
Ig strand B 331..335 CDD:143207 1/3 (33%)
Ig strand C 344..348 CDD:143207 2/4 (50%)
Ig strand E 376..380 CDD:143207 0/3 (0%)
Ig strand F 390..395 CDD:143207 2/4 (50%)
Ig strand G 403..406 CDD:143207 0/2 (0%)
Igsf9NP_001100667.1 IG_like 28..110 CDD:214653 21/83 (25%)
Ig strand B 37..41 CDD:409353 1/3 (33%)
Ig strand C 54..58 CDD:409353 0/3 (0%)
Ig strand E 91..95 CDD:409353 1/3 (33%)
IG_like 143..223 CDD:214653 25/84 (30%)
Ig strand B 154..158 CDD:409353 1/3 (33%)
Ig strand C 167..171 CDD:409353 0/3 (0%)
Ig strand E 189..193 CDD:409353 2/3 (67%)
Ig strand F 203..208 CDD:409353 2/4 (50%)
Ig strand G 216..219 CDD:409353 0/2 (0%)
Ig_3 226..305 CDD:464046 23/91 (25%)
Ig 322..407 CDD:472250 3/11 (27%)
Ig strand B 333..344 CDD:409353 84/335 (25%)
Ig strand C 353..358 CDD:409353
Ig strand E 378..382 CDD:409353
Ig strand F 392..397 CDD:409353
Ig 418..503 CDD:472250
Ig strand B 436..440 CDD:409353
Ig strand C 449..453 CDD:409353
Ig strand E 469..473 CDD:409353
Ig strand F 483..488 CDD:409353
Ig strand G 496..499 CDD:409353
FN3 508..599 CDD:238020
FN3 625..715 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 766..807
PHA03247 <777..1062 CDD:223021
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 819..846
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 869..895
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 942..979
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1016..1079
PDZ-binding. /evidence=ECO:0000250 1177..1179
Blue background indicates that the domain is not in the aligned region.

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