DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-zeta and Ncam2

DIOPT Version :9

Sequence 1:NP_723441.2 Gene:DIP-zeta / 34231 FlyBaseID:FBgn0051708 Length:532 Species:Drosophila melanogaster
Sequence 2:NP_981954.2 Gene:Ncam2 / 288280 RGDID:1303131 Length:837 Species:Rattus norvegicus


Alignment Length:477 Identity:114/477 - (23%)
Similarity:179/477 - (37%) Gaps:110/477 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 SWHLIGALL-----VLAATAGDSTNKIILPQILNGGGGGGGVG-------TAQGK-------HPS 50
            |::|:|.|:     :|..|.  |.:|:.|           .||       ||.|:       :|.
  Rat     6 SFYLLGLLVSSGQALLQVTI--SLSKVEL-----------SVGESKFFTCTAIGEPESIDWYNPQ 57

  Fly    51 GSKTVATGVVPNFGGAAGNGAGGGGPVAGSGTGSTVVGSNGVIVAGG-------GANVPTSNLNI 108
            |.|.::|..|               .:...|..|.:...|..|...|       .|...|....:
  Rat    58 GEKIISTQRV---------------MLQKEGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATV 107

  Fly   109 VVE---EPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAILTVHNHVITRNP--RI 168
            |:|   :..|.|.:.......|.:.::.|.|.:..:..|:|::         ||..:|..|  |.
  Rat   108 VLEIYQKLTFREVLSPQEFKQGEDAEVVCRVSSSPAPAVSWLY---------HNEEVTTIPDNRF 163

  Fly   169 SVTHDKHDRHRTWYLHINNVHEEDRGRYMCQINTVTAKTQFGYLNVV----VPPNIDDSLSSSDV 229
            :|..:.:       |.|.|:::.|.|.|.|: ..|.|:.:..:.:::    |||.|.....|.:.
  Rat   164 AVLANNN-------LQILNINKSDEGIYRCE-GRVEARGEIDFRDIIVIVNVPPAIVMPQKSFNA 220

  Fly   230 IVREGANISLRCRASGSPRPIIKWKRDDNSRIAINKNHIVNEWEGDTLEIT--RISRLDMGAYLC 292
            ....|..::|.|:|||||.|.|.|.| :...|..|:.:|:   :|...|:|  .|...|.|:|:|
  Rat   221 TAERGEEMTLTCKASGSPDPAISWFR-NGKLIEENEKYIL---KGSNTELTVRNIINKDGGSYVC 281

  Fly   293 IASNGVPPTVSKRIKVSVD----FPPMLLIPH--QLVG--APEGFNVTIECFTEAHPTSLNYWTR 349
            .|:|          |...|    |..:.:.||  ||..  ..|..:||:.|..|..|.....|.|
  Rat   282 KATN----------KAGEDQKQAFLQVFVQPHILQLKNETTSENGHVTLICEAEGEPVPEITWKR 336

  Fly   350 GEGPIIHDSHKYKVEATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKNPRGETDGIIRLYVSYPP 414
            ....:.........:..:.:........|.|.:|...|.|.|.|.|.:..|.....:.|.:.|.|
  Rat   337 AIDGVTFSEGDKSPDGRIEVKGQHGRSSLHIRDVKLSDSGRYDCEAASRIGGHQRSMHLDIEYAP 401

  Fly   415 TTASSG--IYSTDTHWGENGIN 434
            ...|:.  .||    |..|.||
  Rat   402 KFVSNQTMYYS----WEGNPIN 419

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-zetaNP_723441.2 IG_like 120..216 CDD:214653 20/101 (20%)
Ig 130..200 CDD:143165 17/71 (24%)
I-set 226..310 CDD:254352 27/85 (32%)
IGc2 233..298 CDD:197706 25/66 (38%)
Ig 313..410 CDD:299845 22/100 (22%)
IG_like 325..410 CDD:214653 18/84 (21%)
Ncam2NP_981954.2 IgI_1_NCAM-2 21..113 CDD:409452 24/119 (20%)
Ig strand B 38..42 CDD:409452 0/3 (0%)
Ig strand C 50..54 CDD:409452 0/3 (0%)
Ig strand E 76..80 CDD:409452 1/3 (33%)
Ig strand F 90..95 CDD:409452 0/4 (0%)
Ig strand G 104..107 CDD:409452 0/2 (0%)
IGc2 128..189 CDD:197706 18/77 (23%)
Ig strand B 130..139 CDD:409353 1/8 (13%)
Ig strand C 145..153 CDD:409353 3/16 (19%)
Ig strand C' 156..159 CDD:409353 1/2 (50%)
Ig strand D 162..167 CDD:409353 2/4 (50%)
Ig strand E 168..175 CDD:409353 2/13 (15%)
IgI_1_MuSK 209..298 CDD:409562 31/102 (30%)
Ig strand B 228..232 CDD:409562 1/3 (33%)
Ig strand C 241..245 CDD:409562 1/3 (33%)
Ig strand E 264..268 CDD:409562 1/3 (33%)
Ig strand F 278..283 CDD:409562 2/4 (50%)
Ig strand G 291..294 CDD:409562 0/2 (0%)
Ig 300..397 CDD:416386 22/96 (23%)
Ig strand A 300..305 CDD:409353 2/4 (50%)
Ig strand A' 309..313 CDD:409353 0/3 (0%)
Ig strand B 317..325 CDD:409353 3/7 (43%)
Ig strand C 331..337 CDD:409353 1/5 (20%)
Ig strand C' 340..343 CDD:409353 0/2 (0%)
Ig strand D 353..359 CDD:409353 0/5 (0%)
Ig strand E 362..368 CDD:409353 1/5 (20%)
Ig strand F 376..384 CDD:409353 4/7 (57%)
Ig strand G 387..397 CDD:409353 2/9 (22%)
Ig_3 401..479 CDD:404760 8/23 (35%)
Ig strand B 418..422 CDD:409353 2/2 (100%)
Ig strand C 431..435 CDD:409353
Ig strand E 458..462 CDD:409353
Ig strand F 472..477 CDD:409353
Ig strand G 486..489 CDD:409353
FN3 496..588 CDD:238020
fn3 594..678 CDD:394996
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
33.000

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