DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-zeta and DIP-lambda

DIOPT Version :9

Sequence 1:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_001334747.1	Gene:	DIP-lambda / 26067049	FlyBaseID:	FBgn0267428	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	431	Identity:	154/431 - (35%)
Similarity:	220/431 - (51%)	Gaps:	47/431 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 EPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHD 176
            :|:|...:.|.|||.||::...|.|.|||.|:|||:..:..|||.:|.|:::.|||:||||:.|:
  Fly    49 DPQFLAKLSNTTVPIGRDISFTCVVDNLGHYRVAWIKSDSKAILGIHTHMVSLNPRLSVTHNGHN 113

  Fly   177 RHRTWYLHINNVHEEDRGRYMCQINTVTAKTQFGYLNVVVPPNI--DDSLSSSDVIVREGANISL 239
               ||.|||:.|...|.|.||||:||...|:..|||:|||||:|  ....:..|.:.:||.:|||
  Fly   114 ---TWKLHISRVQINDSGSYMCQVNTDPMKSLSGYLDVVVPPDILNHPEHNPEDGVCQEGGSISL 175

  Fly   240 RCRASGSPRPIIKWKRDDNSRIAINKNHI----VNEWEGDTLEITRISRLDMGAYLCIASNGVPP 300
            .|..:|.|||.:.|:|:....|.:..:..    ....||:.|.:|.:.|.|||.|.||||||:||
  Fly   176 MCSVTGVPRPKVLWRREAGKEIILRTDGRDKTGFKSVEGERLVLTNVQRSDMGGYNCIASNGIPP 240

  Fly   301 TVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRGEGPI-IHDSHKYKVE 364
            :||||..|.|:|.|.:....||||||....||:||..|..|..||.|.|.||.| :|:.:||.:.
  Fly   241 SVSKRFNVYVNFSPTVKAISQLVGAPVEREVTLECIVEVFPKPLNGWYRSEGNIKLHNGNKYNIS 305

  Fly   365 ATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKNPRGETDGIIRLY-VSYPP-----------TTA 417
            ..| :..|..|:.|||.:::..|.|.|.|.:.|..|:::.:|||. :..||           ||.
  Fly   306 EEV-INIYTWHLNLTIRHLTKSDFGTYSCSSVNALGKSESLIRLQELRLPPKLTTTPTPHMQTTG 369

  Fly   418 SSGIYSTDTHWGENGINNNYAYGGPDSTRSIYAQDKNTRYQSNLNEIGLSEQKSFLDKTQNPLLA 482
            .|......:|  :.|:|....:........|  |.:|..:    || |....|....:..|.:|.
  Fly   370 KSRRKHPASH--KKGLNEVLRFQETHFANQI--QQENEDH----NE-GFDLLKFTNSENSNIVLE 425

  Fly   483 NGNANE---------------ADAESNGARGHNPSMAIAWL 508
            :|:.|.               ...::|...|..||....|:
  Fly   426 SGHINSMINKEDVNIYHPKQYGQEKTNKPSGTIPSTRTPWI 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	47/95 (49%)
		Ig	130..200	CDD:143165	33/69 (48%)
		I-set	226..310	CDD:254352	36/87 (41%)
		IGc2	233..298	CDD:197706	27/68 (40%)
		Ig	313..410	CDD:299845	38/98 (39%)
		IG_like	325..410	CDD:214653	33/86 (38%)
DIP-lambda	NP_001334747.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I11903
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I4644
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		mtm8732
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
	8	8.070