DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-zeta and Ptprq

DIOPT Version :9

Sequence 1:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_001357916.1	Gene:	Ptprq / 237523	MGIID:	1096349	Length:	2301	Species:	Mus musculus

Alignment Length:	330	Identity:	62/330 - (18%)
Similarity:	118/330 - (35%)	Gaps:	99/330 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 VTAKTQFGY-----LNVVVPPNIDDSLSSSDVIVREGANISLRCRASGSPRPIIKWKRDDNSRIA 262
            |.|:|..|.     |:|..||::..::....::..|...|.:..|....|..||...|   .:::
Mouse   375 VAAETSAGVGPKSNLSVFTPPDVPGAVFDLQIVEVEATEIRVSWRKPRQPNGIISQYR---VKVS 436

  Fly   263 INKNHIVNEWEGDTLEITRISRLDMGAYLCIASNGVPPTVSKRIKVSV----------------- 310
            :.::.::       ||.|.::..|  .|:   :|.:.|.:...:...:
Mouse   437 VLESGVI-------LENTLLTGQD--EYI---NNPMTPEIMNLVDPMIGFYEGSGEMSSDLHSLA 489

  Fly   311 ---------DFPPMLLIPHQ----LVGAPEGFNVTIEC------------FTEAHPTSLNYWT-R 349
                     |||....:..|    :|.....:...|..            ||| |..|::.:| .
Mouse   490 SFIYNSHPHDFPARTRVEDQRSPVVVATRNQYMTDIAAEHLSYVIRRLVPFTE-HTISVSAFTVM 553

  Fly   350 GEGP--IIHDSHKYKVEATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKNPRGETDGIIRLYVSY 412
            ||||  ::....:.:|.:::.:..||        |:||....:|....:.|.|:    |..|..|
Mouse   554 GEGPPTVLTVRTREQVPSSIQIINYK--------NISSSSILLYWDPPEYPNGK----ITHYTIY 606

  Fly   413 PPTTASSGIYSTDTHWGENGINNNYAYGGPDSTRSIYAQDKNTRYQ------SNLNEIGLSEQKS 471
            .....::..:...|      ::|::...|         ..|.|||:      :::.|..|||:..
Mouse   607 AMELDTNRAFQMTT------VDNSFLITG---------LKKYTRYKMRVAASTHVGESSLSEEND 656

  Fly   472 FLDKT 476
            ...:|
Mouse   657 LFVRT 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	6/17 (35%)
		Ig	130..200	CDD:143165
		I-set	226..310	CDD:254352	14/83 (17%)
		IGc2	233..298	CDD:197706	13/64 (20%)
		Ig	313..410	CDD:299845	24/115 (21%)
		IG_like	325..410	CDD:214653	21/99 (21%)
Ptprq	NP_001357916.1	FN3	57..151	CDD:238020
		FN3	308..393	CDD:238020	6/17 (35%)
		fn3	399..>441	CDD:365830	7/44 (16%)
		FN3	570..654	CDD:238020	21/110 (19%)
		fn3	668..744	CDD:365830
		FN3	762..850	CDD:238020
		fn3	857..934	CDD:365830
		FN3	951..1049	CDD:238020
		FN3	1056..1137	CDD:238020
		FN3	1152..1233	CDD:238020
		FN3	1247..1337	CDD:238020
		FN3	1342..1421	CDD:238020
		FN3	1432..1535	CDD:238020
		FN3	1542..1638	CDD:238020
		FN3	1645..1734	CDD:238020
		UP_III_II	1759..1928	CDD:297589
		R-PTPc-Q	2033..2256	CDD:350464
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900