DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-zeta and Igsf9b

DIOPT Version :9

Sequence 1:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	XP_011240777.1	Gene:	Igsf9b / 235086	MGIID:	2685354	Length:	1443	Species:	Mus musculus

Alignment Length:	387	Identity:	96/387 - (24%)
Similarity:	149/387 - (38%)	Gaps:	90/387 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 GANVPTSNLNIVVEEPEFTEYIENVTVPAGRNVKLGCSVKN--LGS---YKVAWMHFEQSAILTV 157
            |.|:.....:.:.|||||      ||..||..|.|.|.|.:  .|.   |.|.|..|.....:.:
Mouse    17 GKNLVPGGAHGLREEPEF------VTARAGEGVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFI 75

  Fly   158 H-----NHVITRNPRISVTHDKHDRHRTWYLHINNVHEEDRGRYMCQINTVTAKTQFG------- 210
            .     .||   :|..:.....||:..   |.:..|..||:|.|.|::  :....|:.
Mouse    76 KFGYYPPHV---DPEYAGRASLHDKAS---LRLEQVRSEDQGWYECKV--LMLDQQYDTFHNGSW 132

  Fly   211 -YLNVVVPPNIDDSLSSSDVIVREGANISLRCRASGSPRPIIKWKRDDNSRIAINKNHIVNEWEG 274
             :|.:..||...:: ....:..:||.:|::.|.|.|:|:||:.|.: :.:.:..:..:.|::
Mouse   133 VHLTINAPPTFTET-PPQYIEAKEGGSITMTCTAFGNPKPIVTWLK-EGTLLGASAKYQVSD--- 192

  Fly   275 DTLEITRISRLDMGAYLC----IASNGVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIE- 334
            .:|.:|.:||.|.|||.|    |....|..|     .:.|..||.::.|      ||...|.|.
Mouse   193 GSLTVTSVSREDRGAYTCRAYSIQGEAVHTT-----HLLVQGPPFIVSP------PENITVNISQ 246

  Fly   335 -----CFTEAHPTSLN---YWTRGEGPIIHDSHKYKVEATVGLPAYKTHMKLTIINVSSGDDGIY 391
                 |..||:|.:|.   || :.|.....:..|.:|...:       ...|.|..|...|.|.|
Mouse   247 DALLTCRAEAYPGNLTYTWYW-QDENVYFQNDLKLRVRILI-------DGTLIIFRVKPEDAGKY 303

  Fly   392 KCVAKNPRGET-DGIIRLYVSYPPTTASS--------GIY------------STDTHWGENG 432
            .||..|..|.: .....|.|.||....:.        ||:            :|...|.::|
Mouse   304 TCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDG 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	27/113 (24%)
		Ig	130..200	CDD:143165	21/79 (27%)
		I-set	226..310	CDD:254352	23/87 (26%)
		IGc2	233..298	CDD:197706	21/68 (31%)
		Ig	313..410	CDD:299845	28/106 (26%)
		IG_like	325..410	CDD:214653	25/94 (27%)
Igsf9b	XP_011240777.1	Ig	43..117	CDD:319273	21/79 (27%)
		I-set	141..227	CDD:369462	24/95 (25%)
		Ig	231..323	CDD:386229	27/105 (26%)
		Ig	<355..416	CDD:386229	3/11 (27%)
		Ig	440..504	CDD:319273
		FN3	512..607	CDD:238020
		FN3	623..705	CDD:238020
		PHA03247	<900..1248	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910