DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-zeta and Vsig10

DIOPT Version :10

Sequence 1:NP_723441.2 Gene:DIP-zeta / 34231 FlyBaseID:FBgn0051708 Length:532 Species:Drosophila melanogaster
Sequence 2:NP_001028483.2 Gene:Vsig10 / 231668 MGIID:2448533 Length:558 Species:Mus musculus


Alignment Length:486 Identity:98/486 - (20%)
Similarity:147/486 - (30%) Gaps:162/486 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   129 NVKLGCSVKNLGSYKVAWMH--FEQSAILTVHNHVITRNPRISVTHDKHDRHRTWYLHINNVHEE 191
            ||.|.|...:.....|.|..  .|.:.:::.::.:....||.|:       .....|.|..:..|
Mouse    60 NVTLRCGSASGSRGLVTWYRNDSEPAFLVSFNSSLPPAAPRFSL-------EDAGALRIEALRLE 117

  Fly   192 DRGRYMCQ--IN-----TVTAKTQFGYLNVVVPPNIDDSLSSSDVIVREGANISLRCRASGSPRP 249
            |.|.|.||  :|     .|..:...|...|.|..:...:|.:..:....|:.:...|.::..|.|
Mouse   118 DDGNYTCQEVLNETHWFPVRLRV
ASGPAYVEVNISATGTLPNGTLYAARGSQVDFNCCSAAQPPP 182

  Fly   250 IIKWKRDDNSRIAINKNHIVNEWEGDTLEITRISRLDM-----GAYLCIASNGV----------- 298
            .::|         ..:.|.:.|:.|..|.....:.:.|     |.|.|.|:|.:           
Mouse   183 EVEW---------WIQTHSIPEFLGKNLSANSFTLMLMSQNLQGNYTCSATNVLSGRQRKVTTEL 238

  Fly   299 ----PPTVSKRIKVSVD---------------FPP-------------------MLLIPHQL--- 322
                ||..:.:..|.|.               :|.                   ..|.|.||   
Mouse   239 LVYWPPPSAPQCSVEVSSESTTLELACNWDGGYPDPTFLWTEEPGGTIMGNSKLQTLSPAQLLEG 303

  Fly   323 -----VG----APE------------------------GFNVTIEC-FTEAHPTSLNYWTRG-EG 352
                 ||    .||                        |.|||:.| .:.|:|.:...|.|. ..
Mouse   304 KKFKCVGNHILGPESGASCVVKLSSPLLPSQPMRTCFVGGNVTLTCEVSGANPPARIQWLRNLTQ 368

  Fly   353 PIIHDSHKYKVEATVGLPAYKTHMKLTIINVSSG-DDGIYKCVAKNPRGETDGIIRLYVSYP--- 413
            |.|..|..|.:      ........|||.|.|.. |:|.|.|.|:|..|.....|.|.|..|   
Mouse   369 PAIQPSSHYII------TQQGQSSSLTIHNCSQDLDEGFYYCQAENLVGVRATNIWLSVKEPLNI 427

  Fly   414 ----PTTAS---------SG--IYSTDTHWGENGINNNYAYGGPDSTRSIYAQDKNTRYQSNLNE 463
                .|..|         ||  :|.:...|.:.|    ..:.|.|....:...|.....:....|
Mouse   428 GGIVGTVVSLLLLGLAVVSGLTLYYSPAFWWKGG----STFRGQDMGDVMVLVDSEEEEEEEEEE 488

  Fly   464 IGLSEQKSFLDKTQNPLLANGNANEADAESN 494
                |:|..:            |.|.:.|:|
Mouse   489 ----EEKEDV------------AEEVEQETN 503

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-zetaNP_723441.2 IG_like 120..216 CDD:214653 22/95 (23%)
Ig strand B 130..134 CDD:409405 2/3 (67%)
Ig strand C 143..147 CDD:409405 1/3 (33%)
Ig strand E 178..185 CDD:409405 1/6 (17%)
IgI_1_MuSK 218..310 CDD:409562 19/111 (17%)
Ig strand A 218..221 CDD:409562 0/2 (0%)
Ig strand A' 226..231 CDD:409562 0/4 (0%)
Ig strand B 237..244 CDD:409562 1/6 (17%)
Ig strand C 250..255 CDD:409562 1/4 (25%)
Ig strand C' 257..259 CDD:409562 0/1 (0%)
Ig strand D 267..270 CDD:409562 1/2 (50%)
Ig strand E 275..281 CDD:409562 1/5 (20%)
Ig strand F 288..295 CDD:409562 3/6 (50%)
Ig strand G 302..310 CDD:409562 1/7 (14%)
IG_like 325..410 CDD:214653 29/111 (26%)
Ig strand B 331..335 CDD:143207 2/3 (67%)
Ig strand C 344..348 CDD:143207 0/3 (0%)
Ig strand E 376..380 CDD:143207 1/3 (33%)
Ig strand F 390..395 CDD:143207 2/4 (50%)
Ig strand G 403..406 CDD:143207 0/2 (0%)
Vsig10NP_001028483.2 IG_like 55..140 CDD:214653 20/86 (23%)
Ig strand B 61..65 CDD:409353 2/3 (67%)
Ig strand C 74..78 CDD:409353 1/3 (33%)
Ig strand E 107..111 CDD:409353 1/3 (33%)
Ig strand F 121..125 CDD:409353 1/3 (33%)
IG_like 160..240 CDD:214653 15/88 (17%)
Ig strand B 170..174 CDD:409353 0/3 (0%)
Ig strand C 183..187 CDD:409353 1/12 (8%)
Ig strand E 208..212 CDD:409353 0/3 (0%)
Ig strand F 218..223 CDD:409353 2/4 (50%)
Ig strand G 232..235 CDD:409353 0/2 (0%)
IG_like 341..421 CDD:214653 27/85 (32%)
Ig strand B 345..349 CDD:409353 2/3 (67%)
Ig strand C 359..363 CDD:409353 0/3 (0%)
Ig strand E 386..390 CDD:409353 1/3 (33%)
Ig strand F 401..406 CDD:409353 2/4 (50%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 477..515 8/43 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 532..558
Blue background indicates that the domain is not in the aligned region.

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