DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-zeta and zig-2

DIOPT Version :9

Sequence 1:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_510069.1	Gene:	zig-2 / 192087	WormBaseID:	WBGene00006979	Length:	238	Species:	Caenorhabditis elegans

Alignment Length:	236	Identity:	61/236 - (25%)
Similarity:	92/236 - (38%)	Gaps:	65/236 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 PNIDDSLSSSDVIVREGANISLRCRASGSPRPIIKWKRDDNSRIAINKNHIVNEWEGDTLEITRI 282
            |.:..:.:.:|..|..|....|.|.|:|:|.|.|.|:.:.   :.|......|.:|....:..::
Worm    31 PLLKFTRTPNDSNVTFGEKFVLSCGANGAPLPSIYWELNG---MRIQGEETSNVYENILNDGKQV 92

  Fly   283 SRLDM---------------GAYLCIASNGVPPT--VSK------------------RIKVSVDF 312
            |...|               |||.||..||:...  |:|                  .|.::|||
Worm    93 SNAAMVSSHYRIPCATARNSGAYKCIIDNGLTKLEHVAKVFVGGNKTNCALNDNGAPFISMTVDF 157

  Fly   313 PPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNY-WTRGEGPIIHDSHKYKVEATVGLPAYKTHM 376
              .|.|.:..        |.:.|.:|   |:..: |.:||..:.:|..:|::     .|:    .
Worm   158 --RLEISNNA--------VALSCRSE---TATEWSWHKGEQLLTNDGERYQM-----FPS----G 200

  Fly   377 KLTIINVSSGDDGIYKCVAKNPRGETDGIIRLYVSYPPTTA 417
            .|.|.|:|..|.|.|.|.|:|..|||..|..||    ||.|
Worm   201 DLIIRNISWSDMGEYNCTARNHFGETTAITFLY----PTLA 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653
		Ig	130..200	CDD:143165
		I-set	226..310	CDD:254352	26/118 (22%)
		IGc2	233..298	CDD:197706	20/79 (25%)
		Ig	313..410	CDD:299845	27/97 (28%)
		IG_like	325..410	CDD:214653	25/85 (29%)
zig-2	NP_510069.1	I-set	34..134	CDD:254352	25/102 (25%)
		Ig	34..121	CDD:299845	21/89 (24%)
		Ig	<179..232	CDD:299845	20/61 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900