DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-zeta and IGSF5

DIOPT Version :9

Sequence 1:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	XP_011527774.1	Gene:	IGSF5 / 150084	HGNCID:	5952	Length:	497	Species:	Homo sapiens

Alignment Length:	182	Identity:	43/182 - (23%)
Similarity:	67/182 - (36%)	Gaps:	42/182 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 AGSGTGSTVVGSNGVIVAGGGANVPTSNLNIVVEEPEFTEYIENVTVPAGRNVKLGCSVKNLGSY 142
            ||||:|                       |.|:|.|      :|..|..|...:..|:|..  .:
Human   123 AGSGSG-----------------------NEVIEGP------QNARVLKGSQARFNCTVSQ--GW 156

  Fly   143 KVAWMHFEQSAILTVH--NHVITRNPRISVTHDKHDR--HRTWYLHINNVHEEDRGRYMCQINTV 203
            |:.........:|:|.  ..:|| |.|.  |..::|:  :.|..:.|:||...|.|...|.:...
Human   157 KLIMWALSDMVVLSVRPMEPIIT-NDRF--TSQRYDQGGNFTSEMIIHNVEPSDSGNIRCSLQNS 218

  Fly   204 TAKTQFGYLNVVVPPNIDDSLSSSDVIVREGANISLRCRASGSPR-PIIKWK 254
            ..... .||.|.|...:  .:.|.:::|.|.....:.|..|...| |.|.|:
Human   219 RLHGS-AYLTVQVMGEL--FIPSVNLVVAENEPCEVTCLPSHWTRLPDISWE 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	24/99 (24%)
		Ig	130..200	CDD:143165	18/73 (25%)
		I-set	226..310	CDD:254352	9/30 (30%)
		IGc2	233..298	CDD:197706	7/23 (30%)
		Ig	313..410	CDD:299845
		IG_like	325..410	CDD:214653
IGSF5	XP_011527774.1	IG_like	135..228	CDD:214653	24/104 (23%)
		Ig	<200..230	CDD:299845	9/30 (30%)
		Ig	236..307	CDD:299845	9/32 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143419
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930