DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-zeta and ntm

DIOPT Version :9

Sequence 1:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	XP_004916061.1	Gene:	ntm / 100492453	XenbaseID:	XB-GENE-6045425	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	329	Identity:	107/329 - (32%)
Similarity:	165/329 - (50%)	Gaps:	39/329 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 GVIVAGGGANVPTSNLNIVVEEPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAIL 155
            ||.|..|.|..|.:              ::||||..|.:..|.|:|.|..: :|||::  :|.||
Frog    29 GVPVRSGDAGFPKA--------------MDNVTVRQGDSAILRCTVDNRVT-RVAWLN--RSTIL 76

  Fly   156 TVHNHVITRNPRISVTHDKHDRHRTWYLHINNVHEEDRGRYMCQINTVT-AKTQFGYLNVVVPPN 219
            ...|...:.:||:.:..:...::.   :.|.||...|.|.|.|.:.|.. .||...:|.|.|||.
Frog    77 YTGNDKWSIDPRVVLLANTKSQYS---IEIQNVDIYDEGPYTCSVQTDNHPKTSRVHLIVQVPPR 138

  Fly   220 IDDSLSSSDVIVREGANISLRCRASGSPRPIIKWKRDDNSRIAINKNHIVNEWEGDTLEITRISR 284
            |.|  .||.:.|.||:|:||.|.|:|.|.|::.|:     .::......|:  |.:.||||.|:|
Frog   139 IVD--ISSSIAVNEGSNVSLICIANGRPEPVVNWR-----YLSPKARGFVS--EDEYLEITGITR 194

  Fly   285 LDMGAYLCIASNGVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTR 349
            ...|.|.|.|||.|.....:|:|::|::||.:| ..|.:|||.|....::|...|.|.:..:|.:
Frog   195 EQSGIYECSASNDVSAPDVRRVKLTVNYPPYIL-DAQNIGAPLGHRGILQCEASAVPAADFFWYK 258

  Fly   350 GEGPIIHDSHK-YKVEATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKNPRGETDGIIRLYVSYP 413
             |...:.||.: .|||..      :|..::|.:|||..|.|.|.|:|||..|.::..|.|:..:.
Frog   259 -EDKRLSDSWRGVKVENR------ETISRVTFLNVSEQDYGNYTCMAKNLLGHSNASIILFELFQ 316

  Fly   414 PTTA 417
            .|::
Frog   317 STSS 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	30/96 (31%)
		Ig	130..200	CDD:143165	20/69 (29%)
		I-set	226..310	CDD:254352	31/83 (37%)
		IGc2	233..298	CDD:197706	25/64 (39%)
		Ig	313..410	CDD:299845	33/97 (34%)
		IG_like	325..410	CDD:214653	28/85 (33%)
ntm	XP_004916061.1	Ig	45..133	CDD:299845	29/93 (31%)
		IG_like	45..133	CDD:214653	29/93 (31%)
		IG_like	143..220	CDD:214653	31/83 (37%)
		IGc2	150..209	CDD:197706	25/65 (38%)
		ig	227..311	CDD:278476	30/91 (33%)
		IG_like	230..311	CDD:214653	29/87 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41139
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4412
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		otm47726
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060