DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-zeta and iglon5

DIOPT Version :9

Sequence 1:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	XP_002938252.1	Gene:	iglon5 / 100488314	XenbaseID:	XB-GENE-945713	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	323	Identity:	97/323 - (30%)
Similarity:	152/323 - (47%)	Gaps:	46/323 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 VPTSNLNIV-------VEEPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAILTVH 158
            |..::|.||       |:..||....:|.||..|.|..|.|.:.:..: :|||::  :|.||...
Frog     8 VSLASLGIVMLAQVLFVQCTEFVPPADNYTVSQGDNATLSCLIDDKVT-RVAWLN--RSNILYAG 69

  Fly   159 NHVITRNPRIS-VTHDKHDRHRTWYLHINNVHEEDRGRYMCQINTV-TAKTQFGYLNVVVPPNID 221
            ....:.:.|:. :|:.|.:    :.:.|.:|...|.|.|.|...|. ...|...||.|.||..|.
Frog    70 KDKWSIDSRVQLLTNTKSE----YSIVITHVDVADEGLYTCSFQTEDKPHTSQVYLIVQVPAKIV 130

  Fly   222 DSLSSSDVIVREGANISLRCRASGSPRPIIKWKRDDNSRIAINKNHIVNEW---EGDTLEITRIS 283
            :  .||.|.|.||:|::|:|.|.|.|.|.|.|::             ::|.   ||:.||||.|:
Frog   131 N--ISSSVTVNEGSNVNLQCLAVGKPEPTITWQQ-------------LSEGFSSEGELLEITEIN 180

  Fly   284 RLDMGAYLCIASNGVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWT 348
            |...|.|.|:.||||....:|:::::|::|| .:...:...:|.|...|:.|...|.|.:...|.
Frog   181 RQQAGDYECVTSNGVSVPDTKKVQITVNYPP-YITDVKNAQSPVGRPATLRCKAMAVPPAEFEWY 244

  Fly   349 RGEGPIIHDSHKYKVEATVGLPAYKTHMKLTII---NVSSGDDGIYKCVAKNPRGETDGIIRL 408
            :       |..:..:..|.|| :.||....::|   ||:|...|.|.|:|.|..|..:..:||
Frog   245 K-------DEKRRLISGTEGL-SIKTESSWSVIVFSNVTSRHYGNYTCLASNKLGSFNSSLRL 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	27/97 (28%)
		Ig	130..200	CDD:143165	17/70 (24%)
		I-set	226..310	CDD:254352	32/86 (37%)
		IGc2	233..298	CDD:197706	25/67 (37%)
		Ig	313..410	CDD:299845	27/99 (27%)
		IG_like	325..410	CDD:214653	25/87 (29%)
iglon5	XP_002938252.1	Ig	31..123	CDD:299845	26/98 (27%)
		IG_like	35..123	CDD:214653	26/94 (28%)
		Ig	126..207	CDD:299845	34/95 (36%)
		I-set	128..207	CDD:254352	33/93 (35%)
		I-set	210..299	CDD:254352	25/97 (26%)
		Ig	227..298	CDD:143165	21/78 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4412
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970