DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9541 and ak4

DIOPT Version :9

Sequence 1:	NP_001260273.1	Gene:	CG9541 / 34220	FlyBaseID:	FBgn0032083	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_998464.1	Gene:	ak4 / 406590	ZFINID:	ZDB-GENE-040426-2505	Length:	226	Species:	Danio rerio

Alignment Length:	238	Identity:	51/238 - (21%)
Similarity:	94/238 - (39%)	Gaps:	48/238 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   362 VIGGPGSNKATLCLKAVGLNPGWAHISVGRLLR-NI---TDSAPRANTESFAVKEALAAGDMAPE 422
            ::|.|||.|.|:. :.:..|.|..|:|.|..:| ||   ||:...|.|       .:..|.:.|:
Zfish     9 IMGPPGSGKGTIS-ERIAHNFGLKHLSSGDFVRENISSKTDAGVLAKT-------YINKGLLVPD 65

  Fly   423 KSLNQLLETNLRQLRDRTGIIVDGYPRNLQQVKYFENKYKQRPPIILLDCSKLQLGRGRIDDTVS 487
            ..:.:||...|.:: .:...::||:||.|.|.:...:           .|..         |...
Zfish    66 HVMTRLLLPRLEEM-TKYSWLLDGFPRTLAQAEALNS-----------SCDL---------DVAI 109

  Fly   488 SFRRRLELFREQTL------PMLKILD---TSNRLQIVDGDTDSPSVQREFER---LIR--NHIQ 538
            :....||..:|:..      |..::.:   ...|:|.:|..|....:|:|.:|   |:.  .|.:
Zfish   110 NLNIPLETLKERLRHRWIHPPSGRVYNMCFNPPRIQGLDDITGEALIQQEDDRPEALVARLRHYK 174

  Fly   539 RLLNKTDDIDDSANLGNQMMRNEQTDAILHDLETNVPGAVPTI 581
            .:.....|...:..: .....:.:||.|..::.|.:...:|.|
Zfish   175 DVAKPVIDFYKAKGI-LYTFSDTETDRIWPNINTLLSTKIPAI 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9541	NP_001260273.1	aden_kin_iso1	67..238	CDD:130427
		ADK	70..230	CDD:238713
		aden_kin_iso1	358..521	CDD:130427	38/171 (22%)
		ADK	359..521	CDD:238713	38/171 (22%)
ak4	NP_998464.1	adk	6..210	CDD:273569	49/230 (21%)
ak4	NP_998464.1	ADK	6..192	CDD:238713	45/212 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582283
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23359
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.930