Protein Alignment: CG9541 and AK5

• Sequence 1: NP_001260273.1
• Gene: CG9541
• FlyBaseID: FBgn0032083
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_777283.1
• Gene: AK5
• HGNCID: 365
• Length: 562
• Species: Homo sapiens
• Alignment Length: 495
• Identity: 121/496 (24%)
• Similarity: 204/496 (41%)
• Gaps: 113/496 (23%)

  Fly    63 FDP--PKVPVIFVLGGPGSGKVTHCDTFMQERRGVTHINMMDLLQQYAMGNDMQDFSQLSSKTVT 125
            |||  |:..:|.|:|||||||.|. ...:.||.|..:|::.:||::............|.:|.:|
Human   125 FDPTRPRPKIILVIGGPGSGKGTQ-SLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIIT 188

  Fly   126 -------EVLMLEMK----MAPAAKAYLISGYPRSMRDVVEYSEKIQVVNGVILIS-----WRQS 174
                   |..:.|:|    ..|..:..:|.|:||.:...:.:.::|...:.|:.::     .::.
Human   189 TGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKER 253

  Fly   175 VLQKQIDYGAKLGHVVLSLAKMELENFFKNVMPVADYFDQSDMLLAVNGERAPTEVYKDFRTAVL 239
            :|::....|....:|  ...:..|.||.:|..|:..||.:..:::..:.:|...||:.|...||.
Human   254 LLKRAEQQGRPDDNV--KATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVD 316

  Fly   240 DILSTLENQEAVMNGVTGMGRGIHDIPGSIV-----SVDTAPSQAQQGTQIAEDNDVTNASETAG 299
            :.|  ..|:||        ..|..|:..|::     .:||......||
Human   317 NKL--FPNKEA--------AAGSSDLDPSMILDTGEIIDTGSDYEDQG----------------- 354

  Fly   300 TVLARDLAIERMDGGPNGAVTALKTGTTSADDDSGVVVTQQPKLRQAAGPDESG---SDLP--PI 359
                                          ||...|.           |.|..|   .||.  .|
Human   355 ------------------------------DDQLNVF-----------GEDTMGGFMEDLRKCKI 378

  Fly   360 IWVIGGPGSNKATLCLKAVGLNPGWAHISVGRLLRNITDSAPRANTESFAVKEALAAGDMAPEKS 424
            |::||||||.|.|.|.|.|. ..|:.|:|.|.|||   :.....:..|..:::.:..||:.|...
Human   379 IFIIGGPGSGKGTQCEKLVE-KYGFTHLSTGELLR---EELASESERSKLIRDIMERGDLVPSGI 439

  Fly   425 LNQLL-ETNLRQLRDRTGIIVDGYPRNLQQVKYFENKYKQRPPIILLDCSK-------LQLGRGR 481
            :.:|| |..:..|.|..|.::|||||.::|.:.|..:......:|.:|||.       ||..|..
Human   440 VLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSS 504

  Fly   482 --IDDTVSSFRRRLELFREQTLPMLKILDTSNRLQIVDGD 519
              :|||..:..:|||.:...::|::...:|..:|..::.:
Human   505 LPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAE 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9541	NP_001260273.1	aden_kin_iso1	67..238	CDD:130427	44/187 (24%)
		ADK	70..230	CDD:238713	41/176 (23%)
		aden_kin_iso1	358..521	CDD:130427	53/173 (31%)
		ADK	359..521	CDD:238713	53/172 (31%)
AK5	NP_777283.1	aden_kin_iso1	133..316	CDD:130427	45/186 (24%)
		Adenylate kinase 1. {ECO:0000305|PubMed:19647735}	133..316		45/186 (24%)
		ADK	134..307	CDD:238713	41/176 (23%)
		NMPbind 1. {ECO:0000250|UniProtKB:P00568}	162..193		5/31 (16%)
		LID 1. {ECO:0000250|UniProtKB:P00568}	256..266		1/10 (10%)
		aden_kin_iso1	374..561	CDD:130427	53/176 (30%)
		Adenylate kinase 2. {ECO:0000305|PubMed:19647735}	377..559		53/173 (31%)
		ADK	378..550	CDD:238713	53/172 (31%)
		NMPbind 2. {ECO:0000269|Ref.8}	406..435		8/32 (25%)
		LID 2. {ECO:0000269|Ref.8}	499..509		3/10 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C121819490
eggNOG	1	0.900				E1_COG0563
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	126	1.000	Inparanoid score	I4621
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	1	1.010				D1378291at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			LDO	PTHR23359
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	8	7.960