Protein Alignment Tsp29Fa and CD63

DIOPT Version :8

• Sequence 1: NP_001162915.1
• Gene: Tsp29Fa / 34211
• FlyBaseID: FBgn0032074
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_001244318.1
• Gene: CD63 / 967
• HGNCID: 1692
• Length: 238
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 76/238 (32%)
• Similarity: 127/238 (53%)
• Gaps: 12/238 (5%)

  Fly     6 GSANAVKYTLFGFNLIFLITGIILIAVGAGVGAVYTGYKLFLAGKFFSIPTFLIVIGSFIIIISF 70
            |....||:.|:...|.|....:.|||||.|...|.:...:..|.....:|..:|.:|.|:.:::|
Human     5 GGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAF 69

  Fly    71 FGCWGALKENYCLVLSFSVMLAIIFILELAAGISGYVLRNDASDLIKTSLTYSLNEYNSINPNAT 135
            .||.||.||||||:::|::.|::|.::|:||.|:|||.|:........:....:..|.  ..|.|
Human    70 VGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYP--KNNHT 132

  Fly   136 TKLWDDIQDEFECCGVTSYNDW--ITAFPNGDLPISCC-NVHVGAVGTFTCNNAQSSVADRHKVG 197
            ..:.|.:|.:|:|||..:|.||  |.:.....:|.||| ||.||....|.    :.::   ||.|
Human   133 ASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFN----EKAI---HKEG 190

  Fly   198 CLDGFSGYISAHAVSLGAAGVVIAILQFFGVIFACYIAREIK 239
            |::...|::..:.:.:.||.:.||.::..|::|||.:.:.|:
Human   191 CVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSIR 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp29Fa	NP_001162915.1	Tetraspannin	11..238	CDD:278750	74/230 (32%)
		tetraspanin_LEL	106..210	CDD:239401	30/107 (28%)
CD63	NP_001244318.1	MAP17	33..>70	CDD:318101	8/37 (22%)
		CD63_LEL	105..203	CDD:239419	30/107 (28%)
		Lysosomal targeting motif. {ECO:0000250|UniProtKB:P41731}	234..238

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E33208_3BQQH
Hieranoid	1	1.000
Homologene	1	1.000				H37526
Inparanoid	1	1.050	139	1.000	Inparanoid score	I4430
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900				OOG5_131579
Panther	1	1.100			O	PTHR19282
Phylome	1	0.910		0.705	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R4418
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.890