Protein Alignment LManVI and Man2b1

DIOPT Version :10

• Sequence 1: NP_609253.1
• Gene: LManVI / 34206
• FlyBaseID: FBgn0032069
• Length: 1007
• Species: Drosophila melanogaster
• Sequence 2: XP_006255335.1
• Gene: Man2b1 / 361378
• RGDID: 3039
• Length: 1021
• Species: Rattus norvegicus
• Alignment Length: 1052
• Identity: 414/1052 - (39%)
• Similarity: 583/1052 - (55%)
• Gaps: 118/1052 - (11%)

  Fly     8 VLFVALL--AISVRPSEEACGYEACPKTKTNMINIHMVPHSHDDVGWLKTVDQYFYG---H---- 63
            ||.::.|  .:...|..:|.||:.||.||..|:|:|::||:|||||||||||||:||   |
  Rat    31 VLSISFLIWLLLAAPGAQAAGYKTCPTTKPGMLNVHLLPHTHDDVGWLKTVDQYYYGMDPHLLTF 95

  Fly    64 ----RSNIQHAGVQYIIDTVIAELIKDPARRFIQVETSFFAKWWAEQSETAKQVVRKLVNEGRLE 124
                .|::|||.||||:|:||..|:.||.||||.||.:||::||.:|:...:..||.||.:||||
  Rat    96 MPIVMSDVQHASVQYILDSVIYSLLNDPTRRFIYVEMAFFSRWWKQQTNVTQDAVRNLVRQGRLE 160

  Fly   125 FTGGAWSMNDEAAVNYQSVIDQFTLGLKFLDDTFGSCARPRIGWQIDPFGHSREQASIFAQMGYD 189
            |..|.|.||||||.:|.:::||.||||:||.|||||...||:.|.||||||||||||:|||||:|
  Rat   161 FVNGGWVMNDEAATHYGAIVDQMTLGLRFLQDTFGSDGLPRVAWHIDPFGHSREQASLFAQMGFD 225

  Fly   190 GEFFARMDHRDKNDRIDNLGMEMIWDASDSLSND--EIFTGLLYRHYSAPPGYCFDVHCGDDPII 252
            |.|..|:|::||.:|...|.||.:|.||.||...  ::|||:|..:|:.|...|:||.|.|.|::
  Rat   226 GFFLGRIDYQDKFNRKRKLKMEELWRASASLKPPAADLFTGVLPNNYNPPKDLCWDVLCTDPPVV 290

  Fly   253 -DTKSYDNNVKSRVDDFLSYVTSVAQHYRSNHIMIPMGDDFQYEDAQVNFKNMDKLIKYVNE-RQ 315
             |..|.:.|....||.||:..:|..::||:||.::.||.|||||:|.:.||||||||:.||| :|
  Rat   291 DDPTSPEFNANKLVDYFLNLASSQKKYYRTNHTVMTMGSDFQYENANMWFKNMDKLIRLVNEQQQ 355

  Fly   316 AEGSTFNLFYSTPACYLNSLHEGLQTWPNKTQDFFPYGSDDNSYWTGYFTSRPTQKRFERDGNHI 380
            |.||..::.||||:|||..|::...||..|..|||||....:.:|||||:|||..||:||...:.
  Rat   356 ANGSKVHVLYSTPSCYLWELNKANLTWTVKEDDFFPYADGPHMFWTGYFSSRPALKRYERLSYNF 420

  Fly   381 LQVAKQLSVFAELNTK---QQKEDLEYLREIMGVMQHHDAITGTEKQHVSDDYDRILYDA----- 437
            |||..||........|   ....|...|.|.|.|:|||||:|||.:|:|.:||.:.|...
  Rat   421 LQVCNQLEALVGPEAKVGPYGSGDSAPLNEAMAVLQHHDAVTGTARQNVVNDYAKQLAAGWGPCE 485

  Fly   438 ILGGVNTARDGLRKLTNLPNGEFESCLQLNISECAFTKDDADNVVVTLYNPLAHTSTQYVRVPVK 502
            :|.....||..|.|      ..|..|.::|||.|. ....:::..|.:|||:.......||:||.
  Rat   486 VLVSNALARLSLYK------QNFSFCREINISICP-ASQTSEHFRVIIYNPVGRKVDLMVRLPVS 543

  Fly   503 NENYEVTDEKGRVVASEV--VPVAWQVLALEFRNNDTQHELVFKASVDKIANYYIKKVASQETKN 565
            ...:.|.|...|.::|.|  ||.|:        :...|.||:|.|||..: .:.|..|......|
  Rat   544 EGIFLVKDPNDRRISSNVVMVPSAY--------SKTYQWELLFPASVPAL-GFSIYSVNKMSGHN 599

  Fly   566 VAAHTKSKRSIKAEEANLEVPKRFKKVHSLKNATETFDDDEGETVVQTSQVKLVIDNKTGLLKTV 630
            ..||..:.|..|::...|                          |::...::...|:.||||:.:
  Rat   600 HQAHNLTARPKKSKSRVL--------------------------VIENKYIRATFDSDTGLLRKI 638

  Fly   631 EMNGVSENID----QSYGVYRT--------YDSGAYVFRQYHQADFIVQYEGVEFTVYDGALVKE 683
            |  .:.:||.    |.:..|..        ..||||:||..|:....|.: ..:.|:....||:|
  Rat   639 E--NLEQNISLPVRQGFFWYNASAGDEESPQASGAYIFRPSHRKPLPVSH-WAQVTLVKTNLVQE 700

  Fly   684 VHQQFSEYISQVIRIYEGKNLVEIEWQVGPIEREEEFGREVVIIFNSTIASDGVSYTDSNGREMI 748
            |||.||.:.|||||:|||:..:|:||.||||..::::|:||:..||:.:.:.|..:|||||||::
  Rat   701 VHQNFSAWCSQVIRLYEGQRHLELEWTVGPIPVKDDWGKEVISRFNTPMRTRGQFFTDSNGREIL 765

  Fly   749 KRVKDQRETFTPGLDRQPTAANYYPVTSRIALQDSKKRIAVLNDRAQGGASMLNGQLELMLHRRL 813
            ||..|.|.|:|.. ..:|.|.|||||.:||.:.|...::.||.||:|||:|:|:|.||||:||||
  Rat   766 KRRDDFRPTWTLN-QTEPVAGNYYPVNTRIYITDGHMQLTVLTDRSQGGSSLLDGSLELMVHRRL 829

  Fly   814 VRDDGYGVGEALNEEKYGQPMIARGKVYLILSPSDESTAAER-EAEKEIHLPFWKFFSKNTGSTT 877
            :.||..||.|.|.|...|..:  ||:..:|||...::.|..| .||:|:..|  :....:.||:.
  Rat   830 LVDDERGVAEPLLETDTGDKV--RGRHLVILSSVSDAAARHRLLAEQEVLAP--QVVLAHGGSSP 890

  Fly   878 AAAKSVPSF------NDFPKSVHLLTLEPFNDDEVLLRVENFLDHTE------GQVVSFNIRPIF 930
            ..::: |..      .:.|..||||||..:....:|||:|:.....|      ...|:.|::.:|
  Rat   891 YHSQA-PKMQFSALRRELPPQVHLLTLARWGPKMLLLRLEHQFAVKEDSNRNLSSPVTLNLQNLF 954

  Fly   931 DYLNGVEIRETTLDGNLPLSDMKRFKFHHDSSGQKPDAVEYFTSAHKPLAAEQSQEASEFSVTLH 995
            .......::||||..|.|||.:.|.|:..|:.               |::..........|:||.
  Rat   955 KTFTINYLQETTLAANQPLSRVSRLKWMTDTG---------------PISYPAPSRLDPTSITLQ 1004

  Fly   996 PMQIRTFIIKTE 1007
            |||||||:...:
  Rat  1005 PMQIRTFLASVQ 1016

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManVI	NP_609253.1	GH38N_AMII_LAM_like	38..312	CDD:212121	152/287 (53%)
		PLN02701	40..898	CDD:178304	369/901 (41%)
Man2b1	XP_006255335.1	PLN02701	63..916	CDD:178304	370/903 (41%)
		GH38N_AMII_LAM_like	63..351	CDD:212121	152/287 (53%)