Protein Alignment LManVI and aman-3

DIOPT Version :9

• Sequence 1: NP_609253.1
• Gene: LManVI / 34206
• FlyBaseID: FBgn0032069
• Length: 1007
• Species: Drosophila melanogaster
• Sequence 2: NP_001361919.1
• Gene: aman-3 / 172178
• WormBaseID: WBGene00018594
• Length: 1046
• Species: Caenorhabditis elegans
• Alignment Length: 1047
• Identity: 249/1047 - (23%)
• Similarity: 455/1047 - (43%)
• Gaps: 235/1047 - (22%)

  Fly    29 ACPKTKTNMINIHMVPHSHDDVGWLKTVDQYFYGHRSNIQHAGVQYIIDTVIAELIKDPARRFIQ 93
            |..|::|..:.::::|.:|.|.|||:|.::|   .:|..|      |:|.:...::|:...||:.
 Worm   110 ASKKSRTEKLKVYVLPFTHVDPGWLETFERY---TKSTNQ------ILDNMHQFMMKNEKMRFMW 165

  Fly    94 VETSFFAKWWAEQSETAKQVVRKLVNEGRLEFTGGAWSMNDEAAVNYQSVIDQFTLGLKFLDDTF 158
            .|..||.:||:.|:|..|:.|:|||.|||||...|:|.|.|||...:...:|....|.:|:...|
 Worm   166 AEFVFFERWWSLQNEQVKEDVKKLVTEGRLELATGSWVMTDEANPYFPVSVDNIVEGFQFIHKNF 230

  Fly   159 GSCARPRIGWQIDPFGHSREQASIFAQMGYDGEFFARMDHRDKNDRIDNLGMEMIW-DASDSLSN 222
            |  .:|:..|..||||:|.....:|.:.|.......|:.|:.|........:...| ...|:...
 Worm   231 G--IKPQTMWSNDPFGYSNSVPYLFKKSGVHRTVINRIHHKLKQTLQSQKAIPFKWRQYFDATGE 293

  Fly   223 DEIFTGLL-YRHYSAPPGYCFDV--HCGDDPII------------------DTKSYDNNVKSRVD 266
            |::.|.:| |.||        |:  .||.|..:                  ..|..:.||.::.:
 Worm   294 DDVLTQILPYTHY--------DILNSCGSDASVCCEFDFKRMTHWSCPGPKPEKITNANVAAKAE 350

  Fly   267 DFLSYVTSVAQHYRSNHIMIPMGDDFQYEDAQVNFKNMDKLIKYVNERQAEGSTFNLFYSTPACY 331
            ..::.:..:::.|::..|::..||||:::..:...:..|..|...:|.. :||...:.:.|...|
 Worm   351 KLVNQLEKMSEMYKAPVILMMHGDDFRFDMIEEWNQQHDNFIPVFDEIN-KGSRVEIRFGTFTDY 414

  Fly   332 LNSLHEGLQTW---------PNKTQDFFPYGSDDNSYWTGYFTSRPTQKR-------FERDGNHI 380
            .|.    |:.|         |..:.|||||......|||||:|:||..||       ..|:|:.:
 Worm   415 FND----LEKWYSNNKDSEPPTVSGDFFPYMCALGDYWTGYYTTRPFFKRQGRLLHSLIRNGDIM 475

  Fly   381 LQVAKQLSVFAELNTKQQK-----EDLEYLREIMGVMQHHDAITGTEKQHVSDDYDRILYDAILG 440
            |.:.:       :|.||:|     :.||..|..:.:.|||||||||.|..|.|:|..:|:.:|:
 Worm   476 LSMLR-------VNLKQRKIGENVKRLEAARRNLALFQHHDAITGTSKVSVMDNYSELLHASIV- 532

  Fly   441 GVNTARDGLRK-----LTNLPNG-EFESCLQLNISECAFTKDDADNVVVTLYNPLAHTSTQYVRV 499
            ..|...:.|.|     ...:.:| |.::.:.|..||    |:      :.::|......|...::
 Worm   533 STNIVLENLTKSDIDLYPRIHDGIELQTIVDLESSE----KE------IRIFNSHLFEITDVFKI 587

  Fly   500 PVKNENYEVTDEKGRVVASEVVPVAWQVLALEFRNNDTQHE---LVFKASVDKIANYYIK----- 556
            .|| |...:....|:::.:::.|.        |:.:..:.:   |:|:|:|..::...:|
 Worm   588 RVK-EREVIVSIDGKIIEAQLEPF--------FQKSKVEKDSFLLLFQATVLPLSMMKVKVQRGD 643

  Fly   557 -----KVASQETKN-----------VAAHTKSKRSIKAEEANLEVPKRFKKVHSLKNATETFDDD 605
                 |:|..|.|:           :|:.|.:        .|||.|  :.||.:
 Worm   644 SGGLTKMAKIEAKDTNAWDLGSSWTIASSTSA--------PNLETP--YFKVSN----------- 687

  Fly   606 EGETVVQTSQVKLVIDNKTGLLKTVEMNGVSEN----IDQSYGVYRTYDSGAYVFRQYHQADFIV 666
                           |..||.:::|  |.:|:|    ..||:..|:....|||:.|.:.....|:
 Worm   688 ---------------DPITGAIQSV--NKLSDNSKFHCQQSFYNYKEAGGGAYLMRLHTNPKEII 735

  Fly   667 QYEGVEFTVYDGALVKEVHQQFSEYISQV-IRIYEGKNLVEIEWQVGPIEREEEFGREVVIIFNS 730
            :|:.::.:   |.|.:.::|:.:..:.:: |...||.:..|::..:. |:..:|...|::..| |
 Worm   736 EYQWLKVS---GPLRQSIYQKSTNVLQRLSIHNVEGPSGEEVDISMS-IDITKERNTELMTRF-S 795

  Fly   731 TIASDGVSYTDSNGREMIKRVKDQRETFTPGLDRQPTAANYYPVTSRIALQDSKKRIAVLNDRAQ 795
            |.....::||||.|.::::|          ...:.|..:||||:.:...||..|:|::::::...
 Worm   796 TKWDKPLTYTDSVGMQLLRR----------DFYKLPVQSNYYPMPTAAVLQSGKQRLSIVSNVEH 850

  Fly   796 GGASMLNGQLELMLHRRLVRDDGYGVG---EALNEEKYGQPMIARGKVYLILSPSD--------- 848
            |...:.:|.:|:.:.|.|.:|||.|:|   :|:..:.  :|:..:.|:......||
 Worm   851 GARFLESGTVEINIDRILNQDDGKGLGTGPDAIPIDM--KPVDMKFKLIFDSLESDPTENSRYST 913

  Fly   849 ESTAAEREAEKEIHLPFWKFFSKNTGSTTAAAKSVPSFND-----FPKSVHLLTLEPFNDDEVLL 908
            .|..|::..:..|:.|.  .|::    .....:.:....:     ||..:.|||:.|..|::.||
 Worm   914 HSFRAQQAVQTIIYPPM--MFNR----PPKKEEDIEEIEEISNLKFPCDIQLLTVRPLEDNKQLL 972

  Fly   909 ------------RVENFLDHTEGQVVSFNIRPIFDYLNGVEIRETTLDG-----------NLPLS 950
                        :|.|.....:..::...|:     |...::::|.|.|           .||..
 Worm   973 ILYRHATVCSSQKVGNCGGELKSSLMDLLIK-----LGAKQVQKTDLSGVTRVGGIIKVEYLPDY 1032

  Fly   951 DMKRFKF 957
            ::|.|.|
 Worm  1033 ELKTFDF 1039

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManVI	NP_609253.1	GH38N_AMII_LAM_like	38..312	CDD:212121	78/295 (26%)
		Alpha-mann_mid	359..434	CDD:286360	33/86 (38%)
		Glyco_hydro_38C	482..1002	CDD:285047	110/545 (20%)
aman-3	NP_001361919.1	PLN02701	117..978	CDD:178304	234/972 (24%)
		GH38N_AMII_GMII_SfManIII_like	118..452	CDD:212120	96/357 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810