Protein Alignment LManVI and man2b2

DIOPT Version :10

• Sequence 1: NP_609253.1
• Gene: LManVI / 34206
• FlyBaseID: FBgn0032069
• Length: 1007
• Species: Drosophila melanogaster
• Sequence 2: NP_001106515.1
• Gene: man2b2 / 100127706
• XenbaseID: XB-GENE-1006292
• Length: 990
• Species: Xenopus tropicalis
• Alignment Length: 1102
• Identity: 310/1102 - (28%)
• Similarity: 473/1102 - (42%)
• Gaps: 220/1102 - (19%)

  Fly     7 IVLFVALLAISVRPSEEACGYEACPKTKTNMINIHMVPHSHDDVGWLKTVDQYFYGHRSNIQHAG 71
            |||.|.|.|...     .|.:.|.|      |...::||||.||||:.||.:..:.:.:|
 Frog     2 IVLLVLLSAWGC-----VCTHSAQP------IQAFVIPHSHMDVGWVYTVQESMHAYAAN----- 50

  Fly    72 VQYIIDTVIAELIKDPARRFIQVETSFFAKWW-AEQSETAKQVVRKLVNEGRLEFTGGAWSMNDE 135
               :..||:.||::...||||.||..||..|| .......||.|.:|:.||||||..|...|:||
 Frog    51 ---VYTTVVEELMRGDRRRFIVVEQEFFRLWWKLFAGNVEKQQVHQLMREGRLEFVIGGQVMHDE 112

  Fly   136 AAVNYQSVIDQFTLGLKFLDDTFGSCARPRIGWQIDPFGHSREQASIFAQMGYDGEFFARMDHRD 200
            |.......|.|.|.|..|:.:|||  .|||..|.:||||.|....::||..|::|...:|:|:..
 Frog   113 ALTTIDDQILQLTEGHGFIYETFG--VRPRFSWHVDPFGASAASPTLFAMAGFNGHLISRIDYDT 175

  Fly   201 KNDRIDNLGMEMIWDASDSLSN-DEIFTGLLYRHYSAPPGYC-FDVHCG---------DDPIIDT 254
            |.|..:...::.||.||.|||: .||||.::.::....|.|. |....|         .||..|.
 Frog   176 KADMQNGKELQFIWRASPSLSDKQEIFTHVMDQYSYCTPSYIPFSDRSGFYWNGIAVFPDPPKDG 240

  Fly   255 KSYDNNVKSRVDDFLSYVTSVAQH-------YRSNHIMIPMGDDFQYEDAQVNFKNMDKLIKYVN 312
            ...:.::....|....|..::.::       :||:.::.|.|.|.|:.:|.|.|.|||.|:.|:|
 Frog   241 MYPNMSLPVTADTIHPYAETMVKNIKERAAWFRSSDVLWPWGCDKQFFNASVQFNNMDLLLDYIN 305

  Fly   313 ERQAEGSTFNLFYSTPACYLNSLHEGLQTWPNK-TQDFFPYGSDDNSYWTGYFTSRPTQKRFERD 376
            :....|.|..  |||...|..:|:....||..: :|||.||.||.:..|||::|||...|...|.
 Frog   306 KHTEFGVTVQ--YSTLGDYFKNLYNRNLTWGLRGSQDFLPYSSDSSQAWTGFYTSRNVLKGVARR 368

  Fly   377 GNHILQVAKQLSVFAELNTKQ---------QKEDLEYLREIMGVMQHHDAITGTEKQHVSDDYDR 432
            .:.:|..|:  |.||:...|.         ..|.|..||..:..:||||.|||||...|.|.|
 Frog   369 ASSLLYAAE--SAFAQHLLKHPTGSVEKVWAMEQLRSLRWAVSEVQHHDGITGTESPKVRDMY-- 429

  Fly   433 ILYDAILGGVNTARDGLRKL-----TNLPNGEFESCLQLNISECAFTKDDADNVVVTLYNPLAHT 492
             :.:.:.|..     |:|||     .:|.:.:..||....|:             :|:|||||..
 Frog   430 -IANLLQGAA-----GVRKLMAAIVMDLYSSQANSCGNGYIN-------------ITVYNPLAWD 475

  Fly   493 STQYVRVPVKNENYEVTDEKGRVVASEVVPVAWQVLALEFRNNDTQHELVFKASVDKIANY--YI 555
            .|.:|.||:.|....|.|:.|:.|.:::..      |.|..|....|.||    ..|..:|  |.
 Frog   476 VTTFVLVPMNNSVSGVYDKFGQPVPAQIQN------ATEPSNAFDLHILV----TLKGLSYGRYS 530

  Fly   556 KKVASQETKN--------VAAHTKSKRSIKAEEANLEVPKRFKKVHSLKNATETFDDDEGETVVQ 612
            .|:.|.:..|        :....:.||: ||:..||..|                        :.
 Frog   531 IKLGSCDAANDRLVTGRKITFVRQPKRN-KAKRQNLVTP------------------------IM 570

  Fly   613 TSQVKLVIDNKTGLLKTVEMNGVSENIDQSYGVYRTYDSG---------AYVFRQYHQADFIVQY 668
            .....:|||..|.||.::.....::.:..:......:.:|         .|:|.....|  |..|
 Frog   571 NDCYTVVIDQNTNLLHSITARESNQTVQVTQEFLEYHSNGDISKGPISDNYLFTSTGPA--ISAY 633

  Fly   669 EGVEFTVYDGALVKEVHQQFSEYI----------SQVIRIYEG--KNLV----EIEWQVGPIERE 717
            :.|...:..|.||.|:.|.|...|          |::..:.||  |:||    |..::|||:
 Frog   634 KAVGLEIIAGKLVTEIRQYFYSNITAQTYLYAVYSRIYNVPEGYDKSLVCHHIEQSYRVGPM--- 695

  Fly   718 EEFGREVVIIFNSTIASDGVSYTDSNGREMIKRVKDQRETFTPGLDRQPTAANYYPVTSRIALQD 782
             :..||.:|..::.:.:|.:.|||:||.:|      ||..| ...|....|.||||:.....::|
 Frog   696 -DLNRESIIRTSTDLRTDRLIYTDNNGYQM------QRRQF-KNYDTNTVARNYYPMVRTAYIED 752

  Fly   783 SKKRIAVLNDRAQGGASMLNGQLELMLHRRLVR----DDGYGVGEALNEEKYGQPMIARGKVYLI 843
            :..|:..|::||.|.:|..||::|:||||||..    |..|.:  .||:..     :.|..::|:
 Frog   753 NSTRLVFLSERAHGVSSQDNGEVEIMLHRRLWNNLEWDLNYNL--TLNDTS-----VVRPTIWLM 810

  Fly   844 LSPSDESTAAEREAEKEI-HLPFWKFFSKNTGSTTAAAKSVPSFNDFPKSVHLLTL--------- 898
            |.....:.|..:.....: |.|. ..:|.:||....:.|:.......|.::||..|
 Frog   811 LGSRALAGALYQRLGMALEHRPL-VIYSLHTGQEKRSYKTTDLPITLPDNIHLQILSIPGWFYSS 874

  Fly   899 ---EPFND-------------DEVLLRVENFLDHTEGQV----VSFNIRPIFDYLNGVE-IRETT 942
               |...|             ..||||:::..:..|..|    |:.|::.:...|..|. :.|.:
 Frog   875 RHHEHMQDIHTGNIRDNVADFHRVLLRLQHLYETNEDPVLSKPVTINLQSLLKGLGTVSLVEERS 939

  Fly   943 LDGNLPLSDMKRFKFHHDSSGQKPDAVEYFTSAHKPLAAEQSQEASEFSVTLHPMQIRTFII 1004
            |.|...:..:||:|:..:..|..              ..|.:...|:|::||.|.:|||..:
 Frog   940 LTGTWDIHTLKRWKWKANIKGTD--------------QREHTLGTSDFTITLSPKEIRTLFV 987

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManVI	NP_609253.1	GH38N_AMII_LAM_like	38..312	CDD:212121	100/292 (34%)
		PLN02701	40..898	CDD:178304	271/931 (29%)
man2b2	NP_001106515.1	PLN02701	19..783	CDD:178304	255/852 (30%)
		GH38N_AMII_Epman_like	22..346	CDD:212122	115/335 (34%)