DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LManIV and AT5G13980

DIOPT Version :9

Sequence 1:	NP_609251.2	Gene:	LManIV / 34204	FlyBaseID:	FBgn0032067	Length:	978	Species:	Drosophila melanogaster
Sequence 2:	NP_196902.2	Gene:	AT5G13980 / 831246	AraportID:	AT5G13980	Length:	1024	Species:	Arabidopsis thaliana

Alignment Length:	1043	Identity:	375/1043 - (35%)
Similarity:	549/1043 - (52%)	Gaps:	113/1043 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ILFLSILLVLFAKQSEAVCGYESCPETKANMVNIHLVPHSHNDVGWLKTVDQSYYGYKNKIHHAG 71
            :|.|.|.||    :|..:. |.:........:|:|:|||||:||||||||||.|.|..|.|..|.
plant    11 VLLLGISLV----ESRYMV-YNTSHTIVPGKLNVHVVPHSHDDVGWLKTVDQYYVGSNNSIQVAC 70

  Fly    72 VQYILDSVVSQLLQDPKRRFIQVETAFFAKWWNVQSESMKKVVTKLVNEGRFEFTGGAWSMNDEA 136
            ||.:|||:|..||.|..|:||.||.|||.:|||.|||.:|::|.:|::.|:.|...|...|:|||
plant    71 VQNVLDSIVPALLADKNRKFIYVEQAFFQRWWNEQSEEIKRIVKELIHSGQLELINGGMCMHDEA 135

  Fly   137 NVNYQGVIDQFTVGLKFLNETFGSCGRPRVGWQIDTFGHSREQAAIF-AHMGYDGQFFSRMDHND 200
            ..:|..:|||.|:|.:|:...|..  .||:|||||.||||..||.:. |.:|:|..||.|:|:.|
plant   136 APHYIDMIDQTTLGHRFIIREFNV--TPRIGWQIDPFGHSAVQAYLLGAEVGFDSVFFGRIDYQD 198

  Fly   201 KDTRMNDLTMEMIWDASESM-SGVSLFSGMLYNFYSDTPGFCFDILCTDQPIIDGDSE--ENNVK 262
            ::.|..:.|:|:||..|:|: |...:|:|.....|...||..:..:..|.|::..|.:  :.||:
plant   199 REKRYKEKTLEVIWRGSKSLGSSSQIFAGAFPTNYEPPPGGFYYEITDDSPVVQDDPDLFDYNVQ 263

  Fly   263 QRVDDFISYAKNVSEVYITNHIMVPMGGDFQYEDAKVNYKNMDKLIKYINERQASGSKYNIFYST 327
            :||:.|::.|.:.:.:...||||..||.||:|:.|...|:.|||||.|:|    ...:.|.||||
plant   264 ERVNAFVAAALDQANITRINHIMFTMGTDFRYQYAHTWYRQMDKLIHYVN----LDGRVNAFYST 324

  Fly   328 PSCYLNSLHQSLESWPNKTQDFFPYAHEKNSFWTGFFTSRPTQKRFERDGNHMLQVAKQLSVLAN 392
            ||.|.::.|.:.|:||.||:|:||||...|::|||:|||||..||:.|..:.....|:||.....
plant   325 PSIYTDAKHAANEAWPLKTEDYFPYADRINAYWTGYFTSRPALKRYVRVMSAYYLAARQLEFFKG 389

  Fly   393 LTSEEHKIDLDYLRQVMGVMQHHDAITGTEKQAVSDDYDRMMYEAIVGASNNARDALRLLTNM-- 455
            .:.:..  :.|.|...:.:.|||||::||.||.|::||.:.:....|.|.:....:|..||.:
plant   390 RSQKGP--NTDSLADALAIAQHHDAVSGTSKQHVANDYAKRLAIGYVEAESVVATSLAHLTKVDP 452

  Fly   456 ---PYGEFESCLRLNISECAFTK----DGADNVLVTLYNPLAHSSTQYVRIPVKEENYQVTDEKG 513
               |  .|:.||.||||.|..::    || .:::|..||||.......||:||...:..|.|.:|
plant   453 TLNP--TFQQCLLLNISYCPSSEVNLSDG-KSLIVLAYNPLGWKRVDIVRLPVVGGDVSVHDSEG 514

  Fly   514 RTVPSEVVPVPWQVLAL-EYR------SNDTQ---HELVFKATV-------------NKVSSYSI 555
            ..|.|::||...:.:|| :|.      .:.||   :.|||..||             .|...||.
plant   515 HEVESQLVPFTDEYVALRKYHVEAYLGQSPTQVPKYWLVFSVTVPPLGFTTYTISTAKKTDGYSS 579

  Fly   556 KKVESSEVK-HSSIKKINPREDNNSETVVENSVVKLVMDNHTGRLKSVEMNGVSEKIVQNFGVYK 619
            |...|:.:| ..||..|.......|.:..:.:.:..|    .||      ..::|.:.|.|..|.
plant   580 KSYVSNILKGEQSIINIGHGHLKLSFSTDQGTAINYV----NGR------TSMTEPVKQTFSYYS 634

  Fly   620 SH------------TSCAYTFRQDGDIELF-ENDFEFTVYEGSLVKEVHQHVNDWISQVIRIYEG 671
            ::            .|.||.||.:|...:. |.....||..|.||.||||.:|.||||:.|:|:|
plant   635 AYNGSNDKEPLIPQNSGAYVFRPNGTFPINPEGQVPLTVIHGPLVDEVHQQINPWISQITRVYKG 699

  Fly   672 VSRVELEWMVGPIPIDDKLGSEFVTNFKSEISSNGVFYTDSNGRELMKRVKDKREDFVSDLSRQP 736
            ...||:|::||.|||||.:|.|.||...|.:.||..|||||:||:.:||::|.|.|:..|:: ||
plant   700 KEHVEVEFIVGNIPIDDGIGKEVVTQISSSLKSNKTFYTDSSGRDYIKRIRDYRSDWKLDVN-QP 763

  Fly   737 VSGNFYPVTSRIALQDDTKRLVLLNDRSQGGASLEDGALEMLIHRRHLFNDGGGVGEALNET--- 798
            ::||:||:...|.|||..|...::.||:.||:|:.||.:|:::|||.|.:|..||.|.||||
plant   764 IAGNYYPINHGIYLQDSKKEFSVMVDRAFGGSSIVDGQVELMLHRRLLLDDSRGVAENLNETVCV 828

  Fly   799 -QYGKGLIARGKLYLILDSATDGDTVTERKTEKELFLPFWKFFSKT--------GGVE---ITPS 851
             ....||..:||.|..:|...:| ....|...:|::.|....|::.        |...   |.||
plant   829 QDKCTGLTIQGKYYYRIDPYGEG-AKWRRTFGQEIYSPLLLAFAQQDDGKPMSFGAASFSGIDPS 892

  Fly   852 KSLPDFNDLPQSVHLLTLEFFSEQEILIRFEHFL----DKSEGRVISFNIRDIF--DSLGGLAIR 910
            .||||      :|.||||:...:..:|:|..|..    ||....|.|..::.:|  ..:|.|.
plant   893 YSLPD------NVALLTLQELDDGNVLLRLAHLYEVEEDKELSGVASVELKKLFPGKKIGKLT-- 949

  Fly   911 ETTLDGNMPLSDMKRFKFHAQESGTKPSSVEYSTAQHKPLEAVKSDEASLFAVTLYPMQIRTFII 975
            |.:|..|...|.|::.:...:..|      |.|..:.|..:..:..:.....:.||||:|||.:|
plant   950 EMSLSANQERSTMEKKRLVWKVEG------EGSYGEEKKAKRGREIDPRKLEMELYPMEIRTVLI 1008

  Fly   976 KTE 978
            ..|
plant  1009 HLE 1011

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LManIV	NP_609251.2	GH38N_AMII_LAM_like	39..312	CDD:212121	123/276 (45%)
		Alpha-mann_mid	359..434	CDD:214875	28/74 (38%)
		Glyco_hydro_38C	483..973	CDD:285047	177/547 (32%)
AT5G13980	NP_196902.2	PLN02701	36..820	CDD:178304	311/805 (39%)
AT5G13980	NP_196902.2	GH38N_AMII_LAM_like	37..313	CDD:212121	123/277 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	310	1.000	Domainoid score	I311
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	649	1.000	Inparanoid score	I170
OMA	1	1.010	-	-		QHG55625
OrthoDB	1	1.010	-	-		D201312at2759
OrthoFinder	1	1.000	-	-		FOG0001724
OrthoInspector	1	1.000	-	-		mtm1010
orthoMCL	1	0.900	-	-		OOG6_101099
Panther	1	1.100	-	-	O	PTHR11607
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1279
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840