DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LManIV and AT3G26720

DIOPT Version :9

Sequence 1:	NP_609251.2	Gene:	LManIV / 34204	FlyBaseID:	FBgn0032067	Length:	978	Species:	Drosophila melanogaster
Sequence 2:	NP_189306.1	Gene:	AT3G26720 / 822284	AraportID:	AT3G26720	Length:	1019	Species:	Arabidopsis thaliana

Alignment Length:	1039	Identity:	371/1039 - (35%)
Similarity:	552/1039 - (53%)	Gaps:	114/1039 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LFLSILLVLFAKQSEAVCGYESCPETKANMVNIHLVPHSHNDVGWLKTVDQSYYGYKNKIHHAGV 72
            |:|.:..::....:.....|.:.|......:|:|||||||:||||||||||.|.|..|.|..|.|
plant     8 LYLILAAIVIGGVTSEYIEYNTKPRIVPEKINVHLVPHSHDDVGWLKTVDQYYVGSNNSIRGACV 72

  Fly    73 QYILDSVVSQLLQDPKRRFIQVETAFFAKWWNVQSESMKKVVTKLVNEGRFEFTGGAWSMNDEAN 137
            |.:||||::.||.|..|:||.||.|||.:||..||.:.|..|.|||:.|:.||..|...|:|||.
plant    73 QNVLDSVIASLLDDENRKFIYVEMAFFQRWWRQQSNAKKVKVKKLVDSGQLEFINGGMCMHDEAT 137

  Fly   138 VNYQGVIDQFTVGLKFLNETFGSCGRPRVGWQIDTFGHSREQAAIF-AHMGYDGQFFSRMDHNDK 201
            .:|..:|||.|:|.:|:...||..  ||||||||.||||..||.:. |..|:|..||:|:|:.|:
plant   138 PHYIDMIDQTTLGHQFIKTEFGQV--PRVGWQIDPFGHSAVQAYLLGAEFGFDSLFFARIDYQDR 200

  Fly   202 DTRMNDLTMEMIWDASESM-SGVSLFSGMLYNFYSDTPGFCFDILCTDQPIIDGD-SEENNVKQR 264
            ..|:.:.|:|:||..|:|: |...:|:|:....|....||.|:|.....||.|.. ..:.||::|
plant   201 AKRLREKTLEVIWQGSKSLGSSSQIFTGVFPRHYDPPEGFTFEINDVSAPIQDDPLLFDYNVQER 265

  Fly   265 VDDFISYAKNVSEVYITNHIMVPMGGDFQYEDAKVNYKNMDKLIKYINERQASGSKYNIFYSTPS 329
            |:||::.|.....|..|||||..||.||:|:.|...::.:||.|.|:|:    ..:.|:.|||||
plant   266 VNDFVAAALAQVNVTRTNHIMWLMGTDFRYQYAYSWFRQIDKFIHYVNK----DGRLNVLYSTPS 326

  Fly   330 CYLNSLHQSLESWPNKTQDFFPYAHEKNSFWTGFFTSRPTQKRFERDGNHMLQVAKQLSVLANLT 394
            .|.::.:.:.||||.||.||||||.:.|::|||:|||||..|::.||.:.....|:||..|....
plant   327 IYTDAKYAANESWPLKTDDFFPYADKPNAYWTGYFTSRPAFKKYVRDLSGYYLAARQLEFLRGRD 391

  Fly   395 SEEHKIDLDYLRQVMGVMQHHDAITGTEKQAVSDDY------DRMMYEAIVGASNNARDALRLLT 453
            |.....|:  |...:.:.|||||::||::|.|:.||      ..:..|.:|.:|.:...|.:..|
plant   392 SSGPTTDM--LADALAIAQHHDAVSGTQRQHVAADYALRLSMGYLQAEKLVASSLSFLSAAKSST 454

  Fly   454 NM--PYGEFESCLRLNISECAFTKD---GADNVLVTLYNPLAHSSTQYVRIPVKEENYQVTDEKG 513
            ..  |..:|:.|..||||.|..::.   ...:::|.:||.|.....:.||:||..||..|.|..|
plant   455 EKKNPGTKFQQCPLLNISYCPASEARLLSGKSLVVVVYNSLGWKREEVVRVPVSSENVIVKDASG 519

  Fly   514 RTVPSEVVPVPWQVLALEYRS-----------NDT-QHELVFKATVNKV--SSYSIKKV------ 558
            :.|..:::|:  ..:||..|:           .|| :|.|.|.|:|..:  |||.|...
plant   520 KEVVFQLLPL--SEIALRIRNEYVKAYLGRSPRDTAKHVLAFTASVPPLGFSSYVISDTGRTARG 582

  Fly   559 ------------ESSEVKHSSIK--------KINPREDNNSETVVENSVVKLVMDNHTGRLKSVE 603
                        ::.||...::|        ||.......::...|.|....:..|.|.  |..:
plant   583 LSASYVTSGSMNQNVEVGQGNLKLRYSEEGVKITRHLSTKNQVTAEQSYAYYIGSNGTD--KDPQ 645

  Fly   604 MNGVSEKIVQNFGVYKSHTSCAYTFRQDGDIEL-FENDFEFTVYEGSLVKEVHQHVNDWISQVIR 667
            .:|                  ||.||.||.:.: .:.:.:.|:.:|.|..||||.:|.||||:.|
plant   646 ASG------------------AYVFRPDGVLPIKSKEEAQLTIVQGPLFDEVHQELNSWISQITR 692

  Fly   668 IYEGVSRVELEWMVGPIPIDDKLGSEFVTNFKSEISSNGVFYTDSNGRELMKRVKDKREDFVSDL 732
            :|:|.:..|:|:.:||||.||.:..|.:|...:.:.:||.||||||||:.:||::|.|.|:  ||
plant   693 VYKGKNHAEIEFTIGPIPADDGISKEIITKLTTTMKTNGTFYTDSNGRDFIKRIRDFRTDW--DL 755

  Fly   733 S-RQPVSGNFYPVTSRIALQDDTKRLVLLNDRSQGGASLEDGALEMLIHRRHLFNDGGGVGEALN 796
            . .|||:||:||:...|.:||.|..|.:|.||:.||:|||:|.:|:::|||...:|..||||.||
plant   756 QVYQPVAGNYYPLNLGIYMQDKTSELSVLVDRAVGGSSLENGQIELMLHRRMQHDDIRGVGEILN 820

  Fly   797 ET----QYGKGLIARGKLYLILDSATDGDTVTERKTEKELFLPFWKFFSKTGG------VEITPS 851
            ||    :..|||..:||.|:.:|...|| ....|...:|::.|....|::..|      .:.|.|
plant   821 ETVCLPEGCKGLTIQGKFYVQIDKPGDG-AKWRRTFGQEIYSPLLIAFTEQEGDSWINSHKTTFS 884

  Fly   852 KSLPDFNDLPQSVHLLTLEFFSEQEILIRFEHFLDKSEGRVIS----FNIRDIFDSLGGLAIRET 912
            ...|.:: ||::|.||||:.....|:|:|..|..:..|....|    ..::.:|.:.....::||
plant   885 AFEPSYS-LPKNVALLTLQELENGEVLLRLAHLFEVGEDSEYSVMAKVELKKLFHNKKIREVKET 948

  Fly   913 TLDGNMPLSDMKRFKFHAQESGTKPSSVEYSTAQHKPLEAVKSDEASLFAVTLYPMQIRTFIIK 976
            :|.||...::|::.:...:..|:....|       |..|||   :|....|.|.||:|||.:||
plant   949 SLSGNQEKAEMEKRRLIWKVEGSAGEEV-------KRGEAV---DAEKLVVELVPMEIRTLLIK 1002

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LManIV	NP_609251.2	GH38N_AMII_LAM_like	39..312	CDD:212121	129/275 (47%)
		Alpha-mann_mid	359..434	CDD:214875	29/80 (36%)
		Glyco_hydro_38C	483..973	CDD:285047	172/545 (32%)
AT3G26720	NP_189306.1	PLN02701	36..997	CDD:178304	362/1004 (36%)
AT3G26720	NP_189306.1	GH38N_AMII_LAM_like	38..314	CDD:212121	129/277 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	310	1.000	Domainoid score	I311
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	649	1.000	Inparanoid score	I170
OMA	1	1.010	-	-		QHG55625
OrthoDB	1	1.010	-	-		D201312at2759
OrthoFinder	1	1.000	-	-		FOG0001724
OrthoInspector	1	1.000	-	-		mtm1010
orthoMCL	1	0.900	-	-		OOG6_101099
Panther	1	1.100	-	-	O	PTHR11607
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1279
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840