Protein Alignment LManIV and man2a2

DIOPT Version :10

• Sequence 1: NP_609251.2
• Gene: LManIV / 34204
• FlyBaseID: FBgn0032067
• Length: 978
• Species: Drosophila melanogaster
• Sequence 2: NP_001006777.1
• Gene: man2a2 / 448465
• XenbaseID: XB-GENE-981388
• Length: 909
• Species: Xenopus tropicalis
• Alignment Length: 777
• Identity: 223/777 - (28%)
• Similarity: 354/777 - (45%)
• Gaps: 138/777 - (17%)

  Fly    38 VNIHLVPHSHNDVGWLKTVDQSYYGYKNKIHHAGVQYILDSVVSQLLQDPKRRFIQVETAFFAKW 102
            :.:.:|||||||.||:||.|:.||..        .|:||:::|.:|.:||:|:||..|.:||:||
 Frog   166 LQVFVVPHSHNDPGWIKTFDKYYYDQ--------TQHILNNMVVKLHEDPRRKFIWSEISFFSKW 222

  Fly   103 WNVQSESMKKVVTKLVNEGRFEFTGGAWSMNDEANVNYQGVIDQFTVGLKFLNETFGSCGRPRVG 167
            |:..:...:..|.:||..|:.|.|.|.|.|.||||.:|..:|||...|.::|.:...:  .||.|
 Frog   223 WDNINSQKRAAVRRLVASGQLEMTTGGWVMPDEANTHYFAMIDQMIEGHQWLKKNLDA--TPRSG 285

  Fly   168 WQIDTFGHSREQAAIFAHMGYDGQFFSRMDHNDKDTRMNDLTMEMIWDAS-ESMSGVSLFSGMLY 231
            |.:|.||||.....|............|:.::.|.......::|.:|..: :..|...:|..|:
 Frog   286 WAVDPFGHSSTMPYILRRSNLTSMLIQRVHYSIKKHFAATQSLEFMWRQTWDPDSSTDIFCHMM- 349

  Fly   232 NFYS-DTPGFC---------FD--------ILC----TDQPIIDGDSEENNVKQRVDDFISYAKN 274
            .||| |.|..|         ||        |.|    ..:.|.|     :||.:|.:..:...|.
 Frog   350 PFYSYDVPHTCGPDPKICCQFDFRRLPGGRINCPWKVPPRAITD-----SNVAERANILLDQYKK 409

  Fly   275 VSEVYITNHIMVPMGGDFQYE-----DAKVNYKNMDKLIKYINER-----QASGSKYNIFYSTPS 329
            .|::|.:..::||:|.||:|:     ||:  :.|..||..|:|..     ||.       :.|.|
 Frog   410 KSKLYRSKVVLVPLGDDFRYDKIQEWDAQ--FLNYQKLFDYMNSHPELHVQAQ-------FGTLS 465

  Fly   330 CYLNSLHQSL--------ESWPNKTQDFFPYAHEKNSFWTGFFTSRPTQKRFERDGNHMLQVAKQ 386
            .|.::|::.:        ..:|..:.|||.||..::.:|||::||||..|..:|.....|:.|:.
 Frog   466 DYFDALYKRMGVVPGIKPPDFPVVSGDFFSYADREDHYWTGYYTSRPFYKSMDRVLESHLRGAEI 530

  Fly   387 LSVL----ANLTSEEHKIDL-DY-----LRQVMGVMQHHDAITGTEKQAVSDDYDRMMYEAIVGA 441
            |..|    |.....|.|..| ||     .|:.:|:.|||||||||.|:||..||...:..:::..
 Frog   531 LYSLAINHARKAGTESKYPLSDYALLTDARRNLGLFQHHDAITGTAKEAVVIDYGVRLLHSLMNL 595

  Fly   442 SN---NARDALRLLTNMPYGEFESCLRLNISECAFTKDG----------ADNVLVTLYNPLAHSS 493
            ..   ||...|.:.....|....|....:..|...|::.          |....|.::||:..:.
 Frog   596 KRIIINAAHYLVVADKEKYHYDHSVPFFSTDESRLTQESLPEKTVIKLTASPRYVVVFNPVEQNR 660

  Fly   494 TQYVRIPVKEENYQVTDEKGRTVPSEVVPVPWQVLALEYRSNDTQHELVFKATVNKVSSYSIKKV 558
            ...|.:.|...|.:|..|.|:.|.:::.|| ||.:.   ..|...:::.|.|.:..: ..||.::
 Frog   661 LCVVSLLVNTYNVRVLTEDGQPVAAQLSPV-WQSVT---DMNPDVYQVSFTARLPSL-GLSIFQL 720

  Fly   559 ESSEVKHS---------------SIKK-----INPREDNNSETVVENSVVKLVMDNHTGRLKSVE 603
            .:|...|:               ||||     :...|.:..:..:||..:::.....||.|||::
 Frog   721 HASIDTHTTLKSNVRVHLHGRELSIKKQDVFPVKVAESSTDDFHIENQYMQVWFSGTTGLLKSIK 785

  Fly   604 MNG--VSEKIVQNFGVYKSHT----SCAYTFRQDGDIELF--ENDFEFTVYEGSLVKEV---HQH 657
            ..|  ..:||...|.:|.:.|    |.||.|..||:.:.:  ::.....|.||....||   :||
 Frog   786 RAGEEQEQKINMQFLIYGTRTSKDKSGAYLFLPDGEAKPYTPKDPPVVKVTEGPFYSEVTCQYQH 850

  Fly   658 VNDWISQVIRIY-----EGVSRVELEWMVGPIPIDDKLGSEFVTNFKSEISSNGVFYTDSNG 714
            |    .||:|:|     ||:| :::..:   |.|.|.:..|......::|.|..:|:||.||
 Frog   851 V----QQVMRLYNLPGTEGLS-LDISSL---IDIRDHVNKEIAMRLSTDIQSEDIFFTDLNG 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManIV	NP_609251.2	PLN02701	31..793	CDD:178304	223/777 (29%)
		GH38N_AMII_LAM_like	39..312	CDD:212121	96/300 (32%)
man2a2	NP_001006777.1	PLN02701	128..>906	CDD:178304	223/777 (29%)