Protein Alignment LManIV and man2a2

DIOPT Version :10

• Sequence 1: NP_609251.2
• Gene: LManIV / 34204
• FlyBaseID: FBgn0032067
• Length: 978
• Species: Drosophila melanogaster
• Sequence 2: XP_009296075.2
• Gene: man2a2 / 100333987
• ZFINID: ZDB-GENE-110331-1
• Length: 1177
• Species: Danio rerio
• Alignment Length: 862
• Identity: 231/862 - (26%)
• Similarity: 376/862 - (43%)
• Gaps: 147/862 - (17%)

  Fly    38 VNIHLVPHSHNDVGWLKTVDQSYYGYKNKIHHAGVQYILDSVVSQLLQDPKRRFIQVETAFFAKW 102
            :.:.:|||||||.||:||.|: ||..:       .|:||:::|:::.:||:|:||..|.::||||
Zfish   166 LQVFVVPHSHNDPGWIKTFDK-YYNDQ-------TQHILNNMVTKMAEDPRRKFIWSEISYFAKW 222

  Fly   103 WNVQSESMKKVVTKLVNEGRFEFTGGAWSMNDEANVNYQGVIDQFTVGLKFLNETFGSCGRPRVG 167
            |.......::|:.||:..|:.|...|.|.|.||||.:|..:|||...|.::|....|.  .||.|
Zfish   223 WESADVHKQEVMRKLILSGQLEMVTGGWVMTDEANAHYFAMIDQLIEGHQWLERNLGV--TPRSG 285

  Fly   168 WQIDTFGHSREQAAIFAHMGYDGQFFSRMDHNDKD----TRMNDLTMEMIWDASESMSGVSLFSG 228
            |.:|.||||.....:............|:.::.|.    ||..:......||..   |...:|..
Zfish   286 WAVDPFGHSATMPYLLKRANISSMLIQRVHYSIKKHFAATRSLEFMWRQAWDIE---SSTDMFCH 347

  Fly   229 MLYNFYS-DTPGFCF---DILCT-DQPIIDGDS------------EENNVKQRVDDFISYAKNVS 276
            |: .||| |.|..|.   .|.|. |...:.|..            .:.||.:|....:...:..|
Zfish   348 MM-PFYSYDVPHTCGPDPKICCQFDFKRLPGSRVNCPWKVPPRAINDANVAERAGVLLDQYRKKS 411

  Fly   277 EVYITNHIMVPMGGDFQYEDA---KVNYKNMDKLIKYINERQASGSKYNIFYSTPSCYLNSLHQS 338
            :::.:..::||:|.||:|:.|   ...|.|..||..|:|.......|..  ::|.|.|.::::::
Zfish   412 KLFRSKVLLVPLGDDFRYDKALEWDQQYLNYQKLFDYMNSHPEMHVKAQ--FATLSDYFDAVYKA 474

  Fly   339 --------LESWPNKTQDFFPYAHEKNSFWTGFFTSRPTQKRFERDGNHMLQVAKQLSVLANLTS 395
                    ...:|..:.|||.||..::.:|:|::||||..|..:|.....|:.|:.|..||...:
Zfish   475 NGVTSGARPPDYPVLSGDFFAYADREDHYWSGYYTSRPFYKNLDRILESHLRGAEILYSLAVAHA 539

  Fly   396 EEHKID-----LDY-----LRQVMGVMQHHDAITGTEKQAVSDDYDRMMYEAIVGASN---NA-- 445
            ....::     .||     .|:.:|:.|||||||||.|:||..||...:..::||...   ||
Zfish   540 RHAGVEGRYPVSDYSLLTDARRNIGLFQHHDAITGTAKEAVVIDYGNRLLRSLVGLKRVIINAAH 604

  Fly   446 ------RDALRLLTNMPYGEFESCLRLNISECAFTKDG-ADNVLV---------TLYNPLAHSST 494
                  :|..|.....|:        |...:...|:|. ....|:         .|:||:.....
Zfish   605 FLIIKNKDIYRFYQTEPF--------LETDDRRATQDSLPQRTLIELESSPRYLVLFNPVEQERL 661

  Fly   495 QYVRIPVKEENYQVTDEKGRTVPSEVVPVPWQVLALEYRSNDTQHELVFKATV------------ 547
            ..|.:.|.....:|..|.|:|:|.:        |:.::.|.......|::|:.
Zfish   662 CLVTVLVNSARVRVLTEDGQTLPVQ--------LSAQWMSATEMSGEVYQASFMARLPALGLAVF 718

  Fly   548 ---------NKVSSYSIKKVESSEVKHSSIKKINPREDNNSETV------VENSVVKLVMDNHTG 597
                     ..:.|.::.:|..   :..||:.::|. ...|:||      ::...:.|.....||
Zfish   719 HLYDSADSPMTLRSETLLRVPG---RGQSIRGLDPL-PVRSQTVDGQPFYIQTQSLTLGFSGATG 779

  Fly   598 RLKSVEMNGVSEKI-VQ----NFGVYKS-HTSCAYTFRQDGDIELFENDFE--FTVYEGSLVKEV 654
            .|:|:......::: ||    .:|...| ..|.||.|..||:.:.:.....  ..|.||.|..||
Zfish   780 LLESIRRKDDPQEVRVQIQFLTYGTRPSKDKSGAYLFLPDGNAKPYSQRETPIVRVVEGPLFAEV 844

  Fly   655 HQHVNDWISQVIRIYE--GVSRVELEWMVGPIPIDDKLGSEFVTNFKSEISSNGVFYTDSNGREL 717
            ..|...: .|.:||:.  ||..:.|: :...:.|.|:...|....|.::|.|...||||.||.::
Zfish   845 VAHYQHF-QQTVRIHNVPGVDGLSLD-ITTMVDIRDQNNKELAMRFVTDIQSGDTFYTDLNGFQI 907

  Fly   718 MKRVKDKREDFVSDLSRQPVSGNFYPVTSRIALQDDTKRLVLLNDRSQGGASLEDGALEMLIHRR 782
            ..|         ....:.|:..||||:.|...:||...||.|...::.|..||..|.||:::.||
Zfish   908 QPR---------RYFQKLPLQANFYPMPSTAYIQDSQYRLTLHTAQALGVTSLASGQLEVILDRR 963

  Fly   783 HLFNDGGGVGEALNETQ 799
            .:.:|..|:|:.|.:.:
Zfish   964 LMQDDNRGLGQGLKDNK 980

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManIV	NP_609251.2	PLN02701	31..793	CDD:178304	229/854 (27%)
		GH38N_AMII_LAM_like	39..312	CDD:212121	92/296 (31%)
man2a2	XP_009296075.2	None