Protein Alignment LManIV and man2b2

DIOPT Version :10

• Sequence 1: NP_609251.2
• Gene: LManIV / 34204
• FlyBaseID: FBgn0032067
• Length: 978
• Species: Drosophila melanogaster
• Sequence 2: XP_021333425.1
• Gene: man2b2 / 100003570
• ZFINID: ZDB-GENE-140106-166
• Length: 1006
• Species: Danio rerio
• Alignment Length: 1083
• Identity: 277/1083 - (25%)
• Similarity: 479/1083 - (44%)
• Gaps: 207/1083 - (19%)

  Fly    13 LLVLFAKQSEAVCGYESCPETKANMVNIHLVPHSHNDVGWLKTVDQSYYGYKNKIHHAGVQYILD 77
            ||::...:::|           |..:...::||||.||||:.||.:|.:.|.:.::        .
Zfish     9 LLLMTVSENDA-----------AEKIQAFVIPHSHMDVGWVYTVQESMHAYASNVY--------S 54

  Fly    78 SVVSQLLQDPKRRFIQVETAFFAKWW-NVQSESMKKVVTKLVNEGRFEFTGGAWSMNDEANVNYQ 141
            :||.:|.:...|:||.||..||..|| ||.|:..||.|.:|:.|||.||..|...|:|||..:..
Zfish    55 TVVEELTRVKNRKFIAVEQEFFRLWWTNVASDWHKKQVRQLLLEGRLEFIIGGQVMHDEAVTDVD 119

  Fly   142 GVIDQFTVGLKFLNETFGSCGRPRVGWQIDTFGHSREQAAIFAHMGYDGQFFSRMDHNDKDTRMN 206
            ..|.|.|.|..||.||||.  |||..|.:|.||.|.....:||..|:|....||:|::.||....
Zfish   120 DAILQLTEGHGFLYETFGV--RPRFAWHVDPFGASATTPVLFALAGFDAHLISRIDYDLKDDMQK 182

  Fly   207 DLTMEMIWDASESM-SGVSLFSGMLYNF---------YSDTPGFCFD-ILCTDQPIIDGDSEENN 260
            :..::.:|..|.:: ....:|:..:..|         :|:..||.:: :.....|..||.....:
Zfish   183 NKKLQFVWRGSPTLKEKQEIFTHTMDQFSYCTPSYIPFSNRSGFYWNGVALFPDPPKDGKYPNMS 247

  Fly   261 VKQRVDDFISYAKNV-------SEVYITNHIMVPMGGDFQYEDAKVNYKNMDKLIKYINERQASG 318
            :....:....||:.:       ::.:.::|::.|.|.|.|:.:|.|.:.|||.|:.|||   ...
Zfish   248 LPVTKETVELYAQTMVDNIRLRAQWFRSSHVLWPWGCDKQFYNASVQFSNMDVLMNYIN---THS 309

  Fly   319 SKYNIF--YSTPSCYLNSLHQSLESWPNK-TQDFFPYAHEKNSFWTGFFTSRPTQKRFERDGNHM 380
            .:|.:.  |:|...|..:|||:..||..: .|||.||:.|....||||:.||...|...|..:.:
Zfish   310 DQYGVTVQYATLKDYFQTLHQTNLSWDVRGNQDFLPYSTEPFQAWTGFYGSRNVLKGVARRASSL 374

  Fly   381 LQVAKQLSVLANLTSEEHKIDLDY-------LRQVMGVMQHHDAITGTEKQAVSDDYDRMMYEAI 438
            |..::.|....:::..:..:..::       ||..:..:||||.|||||...|:|.|...:.:.:
Zfish   375 LYASESLFTRYHISYPDGPVQREWALSKLKALRWAVSEVQHHDGITGTESPKVADMYMEHLLQGM 439

  Fly   439 VGA--------------SNNARDALRLLTNMPYGEFESCLRLNISECAFTKDGADNV---LVTLY 486
            :||              ||:..|.::   |.|               ...:..::||   .:.:|
Zfish   440 MGAEELLAAIFLLPQTLSNDIYDQIK---NTP---------------TTARTDSENVPEQHIFVY 486

  Fly   487 NPLAHSSTQYVRIPVKEENYQVTDEKGRTVPSEVVPVPWQVLALEYRSNDTQHELVFKATVN--K 549
            ||||.:.:.||.:.|:.....|.|:.|:.||:::.|      ::|   :.|.::|.|...:.  :
Zfish   487 NPLAWNISTYVNVSVQYAMAVVLDDDGKAVPAQIQP------SME---SSTVYDLFFVVELGGLQ 542

  Fly   550 VSSYSIKKVES-----------SEVKHSSIKKINPRE---DNNSETVVENSVVKLVMDNHTGRLK 600
            ...|:::..:|           ...|.....|.|.|:   .......|.|...||:.|..|..|.
Zfish   543 YRKYTVQFPQSPCDTGSACGATHVAKVVKFNKTNVRQWKKTGRKLLPVLNECYKLMFDQETNLLH 607

  Fly   601 SV--EMNGVSEKIVQNFGVYKSH-------TSCAYTFRQDGDIELFENDFEFTVYEGSLVKEVHQ 656
            |:  ....:..::.|:|..||::       .|..|.|..:|............:..|.::.|:.|
Zfish   608 SITDRSKKIRVRVQQDFWEYKANGDVQSGPISDNYIFTANGSAVPAYKSVVMEIVPGKVISEIRQ 672

  Fly   657 H-------VNDWISQVIRIYEGVS------RVELEWMVGPIPIDDKLGSEFVTNFKSEISSNGVF 708
            :       .|...|.|.|:..|..      |:|..:.|||:.::    .|.|...::.:.:|...
Zfish   673 YFYREEEDANHTYSVVTRVPVGFKGRLSCFRLEQSYKVGPLEVN----RETVFRTRTSLQNNRTL 733

  Fly   709 YTDSNGRELMKRVKDKREDFVSDLSRQPVSGNFYPVTSRIALQDDTKRLVLLNDRSQGGASLEDG 773
            :||:||.::|||.       ....:...|:.|:||:.....::|::.|:|.|::|:.|.|||..|
Zfish   734 FTDNNGYQMMKRT-------YKGYANNTVARNYYPMVRVAYMEDESSRVVFLSERAHGVASLSQG 791

  Fly   774 ALEMLIHRRHLFND---GGGVGEALNETQYGKGLIARGKLYLILDSATDGDTVTERKTEKELFLP 835
            .||:::||| |:|:   ..|....||::.     :.|..|:::|.|.....::.:::..:....|
Zfish   792 QLEVMLHRR-LWNNQEWNQGYNLTLNDSS-----VVRPVLWMMLGSPDSLSSIYQQEAVELQHRP 850

  Fly   836 FWKFFSKTGGVEITPSKSL--------PDFND--LPQSVHLLTLEF----FSEQ----------- 875
            ......:       |.|.|        |..:.  |||::|:.:|..    :|.:
Zfish   851 VVMAIDQ-------PQKLLNQRETFSGPSVHPVVLPQNLHMQSLSIPGWNYSPEHSSGGDEKSEV 908

  Fly   876 ---EILIRFEHFLDKSEGRVIS----FNIRDIFDSLGGLA-IRETTLDGNMPLSDMKRFKFHAQE 932
               .||:|..|..::.|..|:|    .|::::...:|.:: ::|.:|.|...:||::|:.:...|
Zfish   909 NFDRILLRITHLYEEGESPVLSQPTTINLKEVMQGIGKVSKVQECSLTGTWNISDLQRWNWKTDE 973

  Fly   933 SGTKPSSVEYSTAQHKPLEAVKSDEASLFAVTLYPMQIRTFII 975
            :..|.....:|        .|..|    |.||:.|.:||||.|
Zfish   974 TMQKTDKSGFS--------GVTQD----FNVTISPKEIRTFFI 1004

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManIV	NP_609251.2	PLN02701	31..793	CDD:178304	228/848 (27%)
		GH38N_AMII_LAM_like	39..312	CDD:212121	92/291 (32%)
man2b2	XP_021333425.1	PLN02701	20..1002	CDD:178304	271/1057 (26%)
		GH38-57_N_LamB_YdjC_SF	23..348	CDD:483946	108/337 (32%)