DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PIG-U and SPAC1952.01

DIOPT Version :9

Sequence 1:	NP_609238.1	Gene:	PIG-U / 34185	FlyBaseID:	FBgn0032052	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_001342842.1	Gene:	SPAC1952.01 / 3361539	PomBaseID:	SPAC1952.01	Length:	408	Species:	Schizosaccharomyces pombe

Alignment Length:	421	Identity:	126/421 - (29%)
Similarity:	204/421 - (48%)	Gaps:	66/421 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KFFKLLLLGGAVRFYFCRTPLAPMIGNRVEFATPLNSHKRMQEGIFLLQSGIDPYLGDLVHESPL 68
            |...||.:...:::|...|.:|..:..|:|.:||::...|::||::|.::|:|||.|.:.::|||
pombe     8 KLLGLLSISFFLQWYLANTWIAEFLYRRIEVSTPVSGFLRVREGLYLYENGLDPYSGGVFYQSPL 72

  Fly    69 ILSALSGLFQKYPQFLPIFYIILDICTAALLYAMSL-RFVKQKQDQQDKERKEY----------- 121
            :|                   ||:.| ..||..:|: |||             |
pombe    73 LL-------------------ILNYC-CELLGGISVTRFV-------------YTSISTMGGLFV 104

  Fly   122 ---AKDTEELQFGPLDKLDIPELVIVAYLFSPLTVMSCIGMTSTVISN---LFLAFFFYCLVKGM 180
               ||....|....:.....|..:.|.||.:|||.:..|..::.:|.|   |...:|..|....:
pombe   105 YLIAKQARVLDPNQVLSTCSPLWISVIYLLNPLTFLPGIACSADMILNFTTLMTIYFASCGSYAI 169

  Fly   181 LIPCLLVLAF---ETVRSFYPIVLIAPLLLVFSRNSVR-RGVAIAALFIVSCLIVAVANYFVLNS 241
            ...|:.:..|   ..:..|:|..||    |....:|:: |.:.:..||.::.||  :.:.|.|||
pombe   170 YACCMALTVFINPNALLLFFPSYLI----LRKCNSSIKFRQIFVVFLFYLAGLI--ITSGFFLNS 228

  Fly   242 WNFLDGTLGFIFYF--RDLQPNIGLFWYFFTEMFEHFRTMFLITFQLNATVLYLVPLSIKLRKEP 304
            .:||  .:.|..|.  .||.||:||:||||||||..|||.||..|.: ..:::::|:||:|...|
pombe   229 LSFL--KIPFRVYLDSHDLTPNLGLWWYFFTEMFNEFRTFFLFVFAI-LPLMFVLPVSIRLYYLP 290

  Fly   305 LLLATVLVALMAVFRAYPSLGDVGFYLALLPLWKRCWKFMAHGFVVFTFFLVTLSMMGALWHLWI 369
            |.:...|:.|.::|:||||:.|:..:|:|||::.:....|.:..:.....:..|.:..|.:|.||
pombe   291 LPITIALIGLHSLFKAYPSICDLSIFLSLLPIFNKVQDRMRYSLLTNNAIVFALVLGSAFYHSWI 355

  Fly   370 YAGSANANFYFGATLAFSTGQIFLITDLLFA 400
            ..|..|||||:.:.|..:.|....|.|.|.|
pombe   356 TLGCGNANFYYASNLILALGLSLKIMDFLKA 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIG-U	NP_609238.1	PIG-U	10..386	CDD:284205	118/399 (30%)
SPAC1952.01	NP_001342842.1	PIG-U	10..371	CDD:310970	119/402 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	162	1.000	Domainoid score	I967
eggNOG	1	0.900	-	-		E1_KOG2552
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6553
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1191
OMA	1	1.010	-	-		QHG54393
OrthoFinder	1	1.000	-	-		FOG0004125
OrthoInspector	1	1.000	-	-		oto101275
orthoMCL	1	0.900	-	-		OOG6_103076
Panther	1	1.100	-	-	LDO	PTHR13121
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R924
SonicParanoid	1	1.000	-	-		X2867
TreeFam	1	0.960	-	-
	14	13.860