Protein Alignment PIG-U and gab1

DIOPT Version :10

• Sequence 1: NP_609238.1
• Gene: PIG-U / 34185
• FlyBaseID: FBgn0032052
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_001342842.1
• Gene: gab1 / 3361539
• PomBaseID: SPAC1952.01
• Length: 408
• Species: Schizosaccharomyces pombe
• Alignment Length: 421
• Identity: 126/421 - (29%)
• Similarity: 204/421 - (48%)
• Gaps: 66/421 - (15%)

  Fly     4 KFFKLLLLGGAVRFYFCRTPLAPMIGNRVEFATPLNSHKRMQEGIFLLQSGIDPYLGDLVHESPL 68
            |...||.:...:::|...|.:|..:..|:|.:||::...|::||::|.::|:|||.|.:.::|||
pombe     8 KLLGLLSISFFLQWYLANTWIAEFLYRRIEVSTPVSGFLRVREGLYLYENGLDPYSGGVFYQSPL 72

  Fly    69 ILSALSGLFQKYPQFLPIFYIILDICTAALLYAMSL-RFVKQKQDQQDKERKEY----------- 121
            :|                   ||:.| ..||..:|: |||             |
pombe    73 LL-------------------ILNYC-CELLGGISVTRFV-------------YTSISTMGGLFV 104

  Fly   122 ---AKDTEELQFGPLDKLDIPELVIVAYLFSPLTVMSCIGMTSTVISN---LFLAFFFYCLVKGM 180
               ||....|....:.....|..:.|.||.:|||.:..|..::.:|.|   |...:|..|....:
pombe   105 YLIAKQARVLDPNQVLSTCSPLWISVIYLLNPLTFLPGIACSADMILNFTTLMTIYFASCGSYAI 169

  Fly   181 LIPCLLVLAF---ETVRSFYPIVLIAPLLLVFSRNSVR-RGVAIAALFIVSCLIVAVANYFVLNS 241
            ...|:.:..|   ..:..|:|..||    |....:|:: |.:.:..||.::.||  :.:.|.|||
pombe   170 YACCMALTVFINPNALLLFFPSYLI----LRKCNSSIKFRQIFVVFLFYLAGLI--ITSGFFLNS 228

  Fly   242 WNFLDGTLGFIFYF--RDLQPNIGLFWYFFTEMFEHFRTMFLITFQLNATVLYLVPLSIKLRKEP 304
            .:||  .:.|..|.  .||.||:||:||||||||..|||.||..|.: ..:::::|:||:|...|
pombe   229 LSFL--KIPFRVYLDSHDLTPNLGLWWYFFTEMFNEFRTFFLFVFAI-LPLMFVLPVSIRLYYLP 290

  Fly   305 LLLATVLVALMAVFRAYPSLGDVGFYLALLPLWKRCWKFMAHGFVVFTFFLVTLSMMGALWHLWI 369
            |.:...|:.|.::|:||||:.|:..:|:|||::.:....|.:..:.....:..|.:..|.:|.||
pombe   291 LPITIALIGLHSLFKAYPSICDLSIFLSLLPIFNKVQDRMRYSLLTNNAIVFALVLGSAFYHSWI 355

  Fly   370 YAGSANANFYFGATLAFSTGQIFLITDLLFA 400
            ..|..|||||:.:.|..:.|....|.|.|.|
pombe   356 TLGCGNANFYYASNLILALGLSLKIMDFLKA 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-U	NP_609238.1	PIG-U	10..386	CDD:429085	118/399 (30%)
gab1	NP_001342842.1	PIG-U	10..371	CDD:429085	119/402 (30%)