Protein Alignment Bace and MGC108380

DIOPT Version :10

• Sequence 1: NP_609235.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001027480.1
• Gene: MGC108380 / 613072
• XenbaseID: XB-GENE-29099139
• Length: 384
• Species: Xenopus tropicalis
• Alignment Length: 395
• Identity: 164/395 - (41%)
• Similarity: 227/395 - (57%)
• Gaps: 44/395 - (11%)

  Fly     7 VVVLLAALASAELHRVP---------------ILKEQNFVKTRQNVLAEKSYLRTKYQLPSLRSV 56
            |:..:....|..|.|||               ||||  |:||.:...|.|.:...||..    :|
 Frog     5 VLAFICLQLSEGLVRVPLKRYKSARDIMRERGILKE--FMKTHKRDPALKYHFNEKYDF----AV 63

  Fly    57 DEEQLSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDACLTHNQYDSSASSTYVA 121
            ..|.:  .|:..|||.||||||.|:|.||||:|||||||||.:|:|:||..||.::.|.||||.:
 Frog    64 AYEPM--YMDTYYYGEISIGTPPQNFLVLFDTGSSNLWVPSTSCQSEACSNHNLFNPSQSSTYTS 126

  Fly   122 NGESFSIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVD 186
            ||:.||:.||:||:||....|||.|.|||:.:|.|..:..|.|::|..:.||||.||||.:::..
 Frog   127 NGQQFSMSYGSGSVTGVFGYDTVTVQGLSLNNQEFGLTYTESGSSFYYSKFDGIFGMAYPAMSAG 191

  Fly   187 GVAPPFYNMVSQGLVDNSVFSFYLARDGTSTMGGELIFGGSDASLYSGALTYVPISEQGYWQFTM 251
            |.......|:.|.|:...:||.|:     |:..||:||||.|.:||||.:.:.|::::.|||..:
 Frog   192 GATTAMQGMLQQNLLTYPIFSVYM-----SSQSGEVIFGGVDNNLYSGQIQWSPVTQEVYWQIGI 251

  Fly   252 AGSSIDGYSL--CDD-CQAIADTGTSLIVAPYNAYITLSEILNVGEDGY-----LDCSSVSSLPD 308
            ....|:|.:.  |.. ||||.|||||.:..|.....||  :.|:|...|     ::|:||.:||.
 Frog   252 DEFLINGQATGWCSQGCQAIVDTGTSPLTIPQQYMGTL--LQNLGAQNYNGMFVVNCNSVQNLPT 314

  Fly   309 VTFNIGGTNFVLKPSAYIIQSDGNCMSAFE--YM----GTDFWILGDVFIGQYYTEFDLGNNRIG 367
            :||.|.|..|.:.||.||:|::|.|....|  |:    |...|||||||:.|||:.:|:.|||:|
 Frog   315 ITFVINGVQFPIPPSGYIVQTNGYCTVGVEETYLPSQNGQPLWILGDVFLRQYYSVYDMSNNRVG 379

  Fly   368 FAPVA 372
            ||..|
 Frog   380 FAQAA 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_609235.1	pepsin_retropepsin_like	59..369	CDD:472175	143/323 (44%)
MGC108380	NP_001027480.1	A1_Propeptide	19..45	CDD:462326	9/27 (33%)
		pepsin_retropepsin_like	71..383	CDD:472175	143/318 (45%)