Protein Alignment Bace and asp-18

DIOPT Version :10

• Sequence 1: NP_609235.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_507653.2
• Gene: asp-18 / 191310
• WormBaseID: WBGene00013973
• Length: 392
• Species: Caenorhabditis elegans
• Alignment Length: 396
• Identity: 130/396 - (32%)
• Similarity: 203/396 - (51%)
• Gaps: 48/396 - (12%)

  Fly     7 VVVLLAALASAELHRVPILKEQNFVKTRQNVLAE---KSYLRTKYQ------LPSLRSVDEEQLS 62
            :::||....||.:.:||.....:|   |..::.|   .|:|.::.|      .|.|...|:..:.
 Worm     3 LLLLLVTTCSAAVFQVPTTTSGSF---RAKLIREGKYSSFLASRLQQLNTGSQPLLGFSDDPCIG 64

  Fly    63 NSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDAC------LTHNQYDSSASSTYVA 121
            |         |:||:|.||..|..|:.|:||||..:.|.|..|      :..::::::.|:::|.
 Worm    65 N---------ITIGSPPQSAFVFMDTTSANLWVMGSACTSVNCNDPLLGIIKHKFNTTKSTSFVK 120

  Fly   122 NGESFSIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVD 186
            :...|:||||:|..:|||.||||::.||.||.|.|..: |....:|.....|||.|:|:.:|:||
 Worm   121 SNRKFNIQYGSGECSGYLGTDTVEIGGLKIQKQEFGVA-NIVDYDFGTRPIDGIFGLAWPALSVD 184

  Fly   187 GVAPPFYNMVSQGLVDNSVFSFYLAR---DGTSTMGGELIFGGSDASLYSGALTYVPISEQGYWQ 248
            .|.||..|:|||..:|..:|:.:..:   |......|.:.:||.|....:..::|||:|.:.|||
 Worm   185 QVTPPMQNLVSQNQLDAPIFTIFFDKRDPDYYYPSNGLITYGGLDTKNCNANISYVPVSSKTYWQ 249

  Fly   249 FTMAGSSIDGYS-LCDDCQAIADTGTSLIVAPYNAYITLSEILNVGEDGY-----LDCSSVSSLP 307
            |.:.|..:..|: ..:..|||.|||:|....||:....::...|...|.|     :.||:::|||
 Worm   250 FKVDGFQVGTYNRTVNRDQAIMDTGSSWFGLPYSVIAGIATQTNATWDLYASVYTVPCSTMNSLP 314

  Fly   308 DVTFNIGGTNFVLKPSAYIIQ---SDGNCMSAFEYMGTD------FWILGDVFIGQYYTEFDLGN 363
            |:.|.||...|.:....|:..   .||.|  |....|.|      ...||::||.:|.:.||:||
 Worm   315 DLVFTIGAEKFPISAPEYVEDVGLDDGTC--ALAMYGIDASGFGPSVTLGNIFIRRYCSVFDVGN 377

  Fly   364 NRIGFA 369
            .|||||
 Worm   378 ARIGFA 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_609235.1	pepsin_retropepsin_like	59..369	CDD:472175	113/333 (34%)
asp-18	NP_507653.2	pepsin_like	63..383	CDD:133138	113/331 (34%)