Protein Alignment Bace and asp-15

DIOPT Version :10

• Sequence 1: NP_609235.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_741675.1
• Gene: asp-15 / 189740
• WormBaseID: WBGene00012681
• Length: 390
• Species: Caenorhabditis elegans
• Alignment Length: 333
• Identity: 116/333 - (34%)
• Similarity: 176/333 - (52%)
• Gaps: 29/333 - (8%)

  Fly    61 LSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDAC-------LTHNQYDSSASST 118
            |::.|:..|...|::|||.||..|:..:||:|.||....|.|.||       .|..::.|:.||:
 Worm    57 LADYMDEIYTANITVGTPPQSASVVMGTGSANFWVVGAGCTSPACNGFPDSGHTKLKFYSNKSSS 121

  Fly   119 YVANGESFSIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESL 183
            :|.....|.|.|.||:.:|||.||.:.:.||::::|.||.:| :..........||:||:|:..:
 Worm   122 FVDLNRKFFINYPTGACSGYLGTDVLQLGGLTVKNQEFAVTT-QISDQMGHFPLDGVLGLAWPPV 185

  Fly   184 AVDGVAPPFYNMVSQGLVDNSVFSFYLAR-----DGTSTMGGELIFGGSDASLYSGALTYVPISE 243
            |||.:.||..|::.|  :|..:|:.:|.|     .|.|  ||.:.||..|.......:.||.:|.
 Worm   186 AVDQITPPMQNLMPQ--LDAPIFTLWLDRVLQGSQGGS--GGLITFGAIDTKNCDAQVNYVALSS 246

  Fly   244 QGYWQFTMAGSSIDGYSLCDDCQAIADT---GTSLIVAPYNAYITLSEILN--VGEDGYLDCSSV 303
            :.:|||.:.|.:|..|:.....|||:|:   |..|.:|..||.|..::...  ..|...||||::
 Worm   247 KTFWQFPLDGVAIGSYTSMKKDQAISDSGDFGLRLPLAVLNAVIQQTKATYDWTNEFYTLDCSTM 311

  Fly   304 SSLPDVTFNIGGTNFVLKPSAYIIQ---SDGNCMSA-FEYMGTDF---WILGDVFIGQYYTEFDL 361
            .:.||:.|.|||..:.:|...||:.   .:|.|:.| |....|.|   :..|:||:.||...||:
 Worm   312 QTQPDLVFTIGGMQYPVKSVEYILDLGLGNGRCVLAMFTDSSTGFGPSFGFGNVFLRQYCNIFDV 376

  Fly   362 GNNRIGFA 369
            ||.|||||
 Worm   377 GNARIGFA 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_609235.1	pepsin_retropepsin_like	59..369	CDD:472175	114/331 (34%)
asp-15	NP_741675.1	pepsin_retropepsin_like	65..384	CDD:472175	112/323 (35%)