Protein Alignment Bace and asp-9

DIOPT Version :10

• Sequence 1: NP_609235.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_500928.2
• Gene: asp-9 / 182511
• WormBaseID: WBGene00015700
• Length: 390
• Species: Caenorhabditis elegans
• Alignment Length: 384
• Identity: 133/384 - (34%)
• Similarity: 183/384 - (47%)
• Gaps: 69/384 - (17%)

  Fly    42 SYLRTKYQLP--------------SLRSVD------EEQLSNSMNMAYYGAISIGTP-----AQS 81
            |...||||:.              .||..|      .:.:::..:.||:|.|::|||     .|:
 Worm    15 SIFETKYQVRVQRGKLVKHATQKYGLRRFDRLVGGQHQHVADFRDFAYFGNITLGTPIESTAEQT 79

  Fly    82 FKVLFDSGSSNLWVPSNTC----KSDACLTHNQYDSSASSTYVANGESFSIQYGTGSLTGYLSTD 142
            |.|:.|:||||:|||.|:|    |..||....:|..:.||:|..:|..|||.|||||.:||...|
 Worm    80 FLVVLDTGSSNVWVPDNSCGIDDKKSACTYKKKYFGTDSSSYEKDGTPFSISYGTGSASGYFGKD 144

  Fly   143 TVDVNG--LSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDGVAPPFYNMVSQGLVDNSV 205
            |:..:.  |.|:||.|.:: |.....|.:...|||||:.:..|||..|.|||.|.|.|||||..:
 Worm   145 TLCFSDTTLCIKSQIFGQA-NNIAPFFANQEIDGILGLGFTDLAVHSVPPPFVNAVEQGLVDEPI 208

  Fly   206 FSFYLARDG--TSTMGGELIFGGSDASLYSGALTYVPISEQGYWQFTMAGSSID-------GYSL 261
            |:.||...|  ....||...:||.|.......:|::|:::..||||.|.|..||       |:
 Worm   209 FTVYLEHHGIKKEASGGYFTYGGEDPDHCGEIITWIPLTKAAYWQFRMQGIGIDNVNEHKNGW-- 271

  Fly   262 CDDCQAIADTGTSLIVAPYNAYITLSEILNVGEDGYLD-----CSSVSSL-------PDVTFNIG 314
                :.|:|||||.|..|......::.......|.|.|     ||.:.:|       .|:||.|.
 Worm   272 ----EVISDTGTSFIGGPGKVIQDIANKYGATYDEYSDSYVIPCSEIKNLRSLKMKINDLTFEID 332

  Fly   315 GTNFVLKPSAYIIQSDGNC-MSAFEYMGTDF---WILGDVFIGQYYTEFDLGNNRIGFA 369
            ..|.|..|.:      ..| ::.|:..|..|   |||||.||.|:....|:.|.|||.|
 Worm   333 PINLVAHPDS------SECDLTLFDMYGGGFGPSWILGDPFIRQFCNIHDIKNKRIGLA 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_609235.1	pepsin_retropepsin_like	59..369	CDD:472175	124/345 (36%)
asp-9	NP_500928.2	Asp	61..385	CDD:394983	124/336 (37%)