Protein Alignment Bace and asp-3

DIOPT Version :10

• Sequence 1: NP_609235.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_509142.2
• Gene: asp-3 / 180947
• WormBaseID: WBGene00000216
• Length: 398
• Species: Caenorhabditis elegans
• Alignment Length: 396
• Identity: 151/396 - (38%)
• Similarity: 230/396 - (58%)
• Gaps: 39/396 - (9%)

  Fly     5 IAVVVLLAALASAELHRVPILKEQNFVKTRQNVLAEKSYLRTKY---QLPSLRSVDEEQLSNSMN 66
            :.:::.|.||||| :.|:. |:::.:.:.:....:.:.:|:.||   .:|: :....|.||:..|
 Worm     5 VFLLLALVALASA-IQRIK-LEKRTYTREQYKFGSIQEHLKAKYVPGYIPN-KDAFNEGLSDYSN 66

  Fly    67 MAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCK--SDACLTHNQYDSSASSTYVANGESFSIQ 129
            ..|||.::||||.|:|:||||:||||||||...|.  ..||..||::|...||:..|.|.||.||
 Worm    67 AQYYGPVTIGTPPQNFQVLFDTGSSNLWVPCANCPFGDIACRMHNRFDCKKSSSCTATGASFEIQ 131

  Fly   130 YGTGSLTGYLSTDTV----DVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDGVAP 190
            |||||:.|.:..|.|    |....:.::|..|.:|:|||..|..|.||||.||.:::::|:.::.
 Worm   132 YGTGSMKGTVDNDVVCFGHDTTYCTDKNQGLACATSEPGITFVAAKFDGIFGMGWDTISVNKISQ 196

  Fly   191 PFYNM-VSQGLVDNSVFSFYLARDGTS-TMGGELIFGGSDASLYSGALTYVPISEQGYWQFTMAG 253
            |...: .:..:..|.:|:|:|:||... |.|||:....:|.:.|.|.:.:.|:..:.||:..:|.
 Worm   197 PMDQIFANSAICKNQLFAFWLSRDANDITNGGEITLCDTDPNHYVGNIAWEPLVSEDYWRIKLAS 261

  Fly   254 SSIDGYSLCD-DCQAIADTGTSLIVAPYNAYITLSE------ILNVGEDGY-LDCSSVSSLPDVT 310
            ..|||.:... ...:|.||||||:..|.:....:..      :.| ||  | ::||.:.|||::|
 Worm   262 VVIDGTTYTSGPIDSIVDTGTSLLTGPTDVIKKIQHKIGGIPLFN-GE--YEVECSKIPSLPNIT 323

  Fly   311 FNIGGTNFVLKPSAYIIQ-SDGN----CMSAFEYMGTD-------FWILGDVFIGQYYTEFDLGN 363
            ||:||.||.|:...||:| |:||    |:|.|  ||.|       .|||||||||::|:.||.||
 Worm   324 FNLGGQNFDLQGKDYILQMSNGNGGSTCLSGF--MGMDIPAPAGPLWILGDVFIGRFYSVFDHGN 386

  Fly   364 NRIGFA 369
            .|:|||
 Worm   387 KRVGFA 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_609235.1	pepsin_retropepsin_like	59..369	CDD:472175	137/337 (41%)
asp-3	NP_509142.2	pepsin_retropepsin_like	59..393	CDD:472175	139/339 (41%)