Protein Alignment Bace and LOC100493461

DIOPT Version :10

• Sequence 1: NP_609235.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: XP_002938556.2
• Gene: LOC100493461 / 100493461
• XenbaseID: XB-GENE-29081723
• Length: 402
• Species: Xenopus tropicalis
• Alignment Length: 401
• Identity: 169/401 - (42%)
• Similarity: 229/401 - (57%)
• Gaps: 40/401 - (9%)

  Fly     3 KTIAVVVLLAALASAELHRVPILK------------EQN--FVKTRQNVLAEKSYLR---TKYQL 50
            |.:.::|....||: .|.|||::|            |.|  ::..:.::.|.| |.:   ..|.|
 Frog     2 KVLLILVGCIQLAT-PLERVPLVKFKSIRSHLWQRDELNEFWLHHQPHIFARK-YTQCFPPPYSL 64

  Fly    51 PSLRSVDEEQLSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDACLTHNQYDSSA 115
            .:  ....|.|.:.||..|||.||:|||.|:|.|:||:||||.||||:.|.|:||..|.::.|..
 Frog    65 AA--GTTTEYLVDYMNAQYYGEISVGTPPQNFSVVFDTGSSNFWVPSSYCLSEACQVHERFKSFE 127

  Fly   116 SSTYVANGESFSIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAY 180
            |::|...|..|||.||||.|.|....||:.::.:||:.|.|.||..|||..|..|.|||:||:.|
 Frog   128 STSYEHGGRPFSIHYGTGQLVGVTGRDTLRISNMSIEGQDFGESILEPGRTFVLAQFDGVLGLGY 192

  Fly   181 ESLAVDGVAPPFYNMVSQGLVDNSVFSFYLARDGTSTMGGELIFGGSDASLYSGALTYVPISEQG 245
            .||||.|..|.|..:|:|.||:..:|||:|.||..|..||||||||.|.|||.|.:.::|::|:|
 Frog   193 PSLAVAGAVPVFDRIVNQKLVEQQLFSFHLNRDYDSEYGGELIFGGIDHSLYKGQIHWIPLTEKG 257

  Fly   246 YWQFTMAGSSIDGYSL-C-DDCQAIADTGTSLIVAPYNAYITLSEILNV-----GEDGY-LDCSS 302
            |||..:....:||.:: | ..||.|.|:|||||..|......|.|:|..     ||  | ||||.
 Frog   258 YWQIRLDNVKVDGEAMFCQSSCQVIVDSGTSLITGPKAEIKKLQELLGATPTLFGE--YILDCSR 320

  Fly   303 VSSLPDVTFNIGGTNFVLKPSAYII----QSDGNCMSAFEYMGTD-----FWILGDVFIGQYYTE 358
            |||||.|||.||..::.|.|..|.|    |....|::.|:.|...     .|||||:|:.::|:.
 Frog   321 VSSLPRVTFTIGQRDYTLTPEQYTIKERSQKSDFCLTGFQAMDISTKDGPLWILGDIFMSKFYSV 385

  Fly   359 FDLGNNRIGFA 369
            ||..::|||.|
 Frog   386 FDREHDRIGLA 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_609235.1	pepsin_retropepsin_like	59..369	CDD:472175	152/326 (47%)
LOC100493461	XP_002938556.2	A1_Propeptide	19..45	CDD:462326	6/25 (24%)
		pepsin_retropepsin_like	75..397	CDD:472175	151/324 (47%)