Protein Alignment: emb and Xpo5

• Sequence 1: NP_001303316.1
• Gene: emb
• FlyBaseID: FBgn0020497
• Length: 1063
• Species: Drosophila melanogaster
• Sequence 2: NP_082474.1
• Gene: Xpo5
• MGIID: 1913789
• Length: 1204
• Species: Mus musculus
• Alignment Length: 1075
• Identity: 201/1076 (19%)
• Similarity: 365/1076 (34%)
• Gaps: 327/1076 (30%)

  Fly    63 ILEYSQNQRTKFYALQILEEVIKTRWKVLPRNQCEGIKKYVVSLIIKTSSDPIVMEQNKVYLNKL 127
            :.|.:|....:.:.|||||.|:|.||..:.|.:...:|..|:.| |...:..|:.|:|.: .:.|
Mouse    54 LAEKTQIAIVRHFGLQILEHVVKFRWNSMSRLEKVYLKNSVMEL-IANGTLRILEEENHI-KDVL 116

  Fly   128 NMILVHILKREWPRNWETFISDIVGASKTNESLCMNNMVILKNLSEEVFDFS------QGQITQT 186
            :.|:|.::|||||::|...:.::....:..|:.....|.||..|:|:|..|.      :..|.||
Mouse   117 SRIVVEMIKREWPQHWPDMLMELDTLFRQGETQRELVMFILLRLAEDVVTFQTLPTQRRRDIQQT 181

  Fly   187 KAKHLKDTM----------CSEFSQIFTLCSFVLENSMNAALIHVTLETLLRFLNWIPLGYIF-- 239
            ..::::..:          .:::.|:.|..|...|...|..:....|.||..:::|:.|.:|.
Mouse   182 LTQNMERILNFLLNTLQENVNKYQQMKTDSSQEAEAQANCRVSVAALNTLAGYIDWVSLNHITAE 246

  Fly   240 ETQQIETLIFKFLSVPMFRNVTLKCLSEIAGLTAANYDENFATLFKDTMVQLEQIVGQNMNMNHV 304
            ..:.:|||                ||.                                  :|
Mouse   247 NCKLVETL----------------CLL----------------------------------LN-- 259

  Fly   305 FKHGSDTEQELVLNLAMFLCTFLKEHGKLVEDAKYVDYL--NQALMYLVMISEVED----VEVFK 363
                   ||||.|..|..|...:...||| ||.|.:..|  :.|:.|::..::..|    ||...
Mouse   260 -------EQELQLGAAECLLIAVSRKGKL-EDRKRLMILFGDVAMHYILSAAQTADGGGLVEKHY 316

  Fly   364 ICLE-------------------------------YWNS-LVEDLYNSEFF----HPTLESTKRQ 392
            :.|:                               |..| |....:.|:|.    |.|..:..|.
Mouse   317 LFLKRLCQVLCALGNLLCALLALDANIQTPINFGMYLESFLAFTTHPSQFLRSSTHMTWGALFRH 381

  Fly   393 QVYPRRRFYAPILSKVRFIMISRMAKPEEVLVVENENGEVVR-EFMKDTNSINLYKNMR----ET 452
            :|..|......::.|.....::.:.|.......::.:.|..| :|..|.:....:.:.|    |.
Mouse   382 EVLSRDPALLAVIPKYLRASMTNLVKMGFPSKTDSPSCEYSRFDFDSDEDFNAFFNSSRAQHGEV 446

  Fly   453 LVFLTHLDSVDTDRIMTLKLLNQVNGSEFSWKNLNT----LCWAIGSISGAFCE---------ED 504
            :..:..||...:.::....|..|::.|      ::|    .|...|:..|.||.         |.
Mouse   447 VRCVCRLDPKTSFQMAAEWLKYQLSAS------IDTGPVNSCSTAGTGEGGFCSIFSPSYVQWEA 505

  Fly   505 EKRFLVTVIK-----------------DLLGLCEQKKGKDNKAIIASNIMYVVGQYPRFLRAHWK 552
            ...||.:||.                 :||.|....:.||  .::.|.::..|.....|:.....
Mouse   506 MTFFLESVINQMFRTLDKEELPVSDGIELLQLVLNFEIKD--PLVLSCVLTNVSALFPFVTYKPA 568

  Fly   553 FLKTVVNKLFEFMHETHDGVQDM--------------ACDTFIKIAIKCRRYFVTIQPNEACTFI 603
            ||..|.:|||.|:  |.:.|.:.              ||.:..|:   ||.|...:.||     .
Mouse   569 FLPQVFSKLFSFV--TFESVGESKAPRTRAVRNVRRHACSSINKM---CRDYPDLVLPN-----F 623

  Fly   604 DEILTTMSSIICD---LQPQQVHTFYEAVGYMISAQVDQVQQDVLIERYMQLPNQVW-DDIISRA 664
            |.:.:.:..::.:   |...:.....||:..:.:...|..:|.:.:|..|.....:| .:.:.||
Mouse   624 DMLYSHVKQLLSNELLLTQMEKCALMEALVLVSNQFKDYERQKLFLEELMAPVVNIWLSEEMCRA 688

  Fly   665 SKNVDFLKNMTAVKQLGSILKTNVAACK---ALGHAYVIQLGRIYLDMLNVYKITS-----ENII 721
            ..::|     :.:..:|:.||:...|.:   .|..|   ::......:|.|.:.||     |...
Mouse   689 LSDID-----SFIAYVGADLKSCDPAVEDPCGLNRA---RMSFCVYSILGVMRRTSWPSDLEEAK 745

  Fly   722 QAIEVNGVNVNNQPLIKTMHVVKKETLNLISEWVSRSNDNQLVMDNFIPPLLDAILLDYQRCKVP 786
            ....|.|...:..|:.:          |..:|.:.|..||.|.:
Mouse   746 AGGFVVGYTPSGNPIFR----------NPCTEQILRLLDNLLAL--------------------- 779

  Fly   787 SAREPKVLSAMAIIVHKLRQHITNEVPKIFDAV---FECTLDMINK-------------NFEDFP 835
                             :|.|.|...|::...:   |...||::..             .|.|.|
Mouse   780 -----------------VRTHNTLYTPEMLTKMAEPFTKALDIVESEKTAILGLPQPLLEFNDHP 827

  Fly   836 QHRLS------FYELLQAVNAHCFKAFLNIPPAQFKLVFDSVVWAFKHTMRNVADMGLNILFKML 894
            .:|.:      |:.:|.   .:|:.......|            :.:.....|.|:...:|....
Mouse   828 VYRTTLERMQRFFGILY---ENCYHILGKAGP------------SMQQDFYTVEDLASQLLGSAF 877

  Fly   895 QNLDQHPG-----------------AAQSFYQTYFTDILMQIFSVVTDTSHTAGLPNHAIILAYM 942
            .||:..|.                 .....|:|..:.||..:|:.:           | :.|:..
Mouse   878 VNLNNIPDFRLRSMLRVFVKPLVLFCPSEHYETLISPILGPLFTYL-----------H-MRLSQK 930

  Fly   943 FSLVENRKITVNLGPI----PDNMIFIQEYVASLL 973
            :.::..|.|......|    |::...::|.:..:|
Mouse   931 WHVINQRSILCGEDEIAEDNPESQEMLEEQLVRML 965

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
emb	NP_001303316.1	CRM1	13..1023	CDD:227432	201/1076 (19%)
		IBN_N	43..109	CDD:197981	16/46 (35%)
		Xpo1	120..265	CDD:285575	36/163 (22%)
		CRM1_C	701..1015	CDD:285920	48/322 (15%)
Xpo5	NP_082474.1	Necessary for interaction with Ran. {ECO:0000250|UniProtKB:Q9HAV4}	1..108		17/55 (31%)
		IBN_N	33..100	CDD:197981	16/47 (34%)
		Xpo1	109..271	CDD:285575	44/222 (20%)
		Necessary for interaction with ILF3. {ECO:0000250|UniProtKB:Q9HAV4}	533..640		26/119 (22%)
		Pre-siRNA binding. {ECO:0000250|UniProtKB:Q9HAV4}	641..642		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG5101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D40069at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910