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Protein Alignment emb and Xpo5

DIOPT Version :9

Sequence 1:	NP_001303316.1	Gene:	emb / 34167	FlyBaseID:	FBgn0020497	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	NP_082474.1	Gene:	Xpo5 / 72322	MGIID:	1913789	Length:	1204	Species:	Mus musculus

Alignment Length:	1075	Identity:	201/1075 - (18%)
Similarity:	365/1075 - (33%)	Gaps:	327/1075 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 ILEYSQNQRTKFYALQILEEVIKTRWKVLPRNQCEGIKKYVVSLIIKTSSDPIVMEQNKVYLNKL 127
            :.|.:|....:.:.|||||.|:|.||..:.|.:...:|..|:.| |...:..|:.|:|.: .:.|
Mouse    54 LAEKTQIAIVRHFGLQILEHVVKFRWNSMSRLEKVYLKNSVMEL-IANGTLRILEEENHI-KDVL 116

  Fly   128 NMILVHILKREWPRNWETFISDIVGASKTNESLCMNNMVILKNLSEEVFDFS------QGQITQT 186
            :.|:|.::|||||::|...:.::....:..|:.....|.||..|:|:|..|.      :..|.||
Mouse   117 SRIVVEMIKREWPQHWPDMLMELDTLFRQGETQRELVMFILLRLAEDVVTFQTLPTQRRRDIQQT 181

  Fly   187 KAKHLKDTM----------CSEFSQIFTLCSFVLENSMNAALIHVTLETLLRFLNWIPLGYIF-- 239
            ..::::..:          .:::.|:.|..|...|...|..:....|.||..:::|:.|.:|.
Mouse   182 LTQNMERILNFLLNTLQENVNKYQQMKTDSSQEAEAQANCRVSVAALNTLAGYIDWVSLNHITAE 246

  Fly   240 ETQQIETLIFKFLSVPMFRNVTLKCLSEIAGLTAANYDENFATLFKDTMVQLEQIVGQNMNMNHV 304
            ..:.:|||                ||.                                  :|
Mouse   247 NCKLVETL----------------CLL----------------------------------LN-- 259

  Fly   305 FKHGSDTEQELVLNLAMFLCTFLKEHGKLVEDAKYVDYL--NQALMYLVMISEVED----VEVFK 363
                   ||||.|..|..|...:...||| ||.|.:..|  :.|:.|::..::..|    ||...
Mouse   260 -------EQELQLGAAECLLIAVSRKGKL-EDRKRLMILFGDVAMHYILSAAQTADGGGLVEKHY 316

  Fly   364 ICLE-------------------------------YWNS-LVEDLYNSEFF----HPTLESTKRQ 392
            :.|:                               |..| |....:.|:|.    |.|..:..|.
Mouse   317 LFLKRLCQVLCALGNLLCALLALDANIQTPINFGMYLESFLAFTTHPSQFLRSSTHMTWGALFRH 381

  Fly   393 QVYPRRRFYAPILSKVRFIMISRMAKPEEVLVVENENGEVVR-EFMKDTNSINLYKNMR----ET 452
            :|..|......::.|.....::.:.|.......::.:.|..| :|..|.:....:.:.|    |.
Mouse   382 EVLSRDPALLAVIPKYLRASMTNLVKMGFPSKTDSPSCEYSRFDFDSDEDFNAFFNSSRAQHGEV 446

  Fly   453 LVFLTHLDSVDTDRIMTLKLLNQVNGSEFSWKNLNT----LCWAIGSISGAFCE---------ED 504
            :..:..||...:.::....|..|::.|      ::|    .|...|:..|.||.         |.
Mouse   447 VRCVCRLDPKTSFQMAAEWLKYQLSAS------IDTGPVNSCSTAGTGEGGFCSIFSPSYVQWEA 505

  Fly   505 EKRFLVTVIK-----------------DLLGLCEQKKGKDNKAIIASNIMYVVGQYPRFLRAHWK 552
            ...||.:||.                 :||.|....:.||  .::.|.::..|.....|:.....
Mouse   506 MTFFLESVINQMFRTLDKEELPVSDGIELLQLVLNFEIKD--PLVLSCVLTNVSALFPFVTYKPA 568

  Fly   553 FLKTVVNKLFEFMHETHDGVQDM--------------ACDTFIKIAIKCRRYFVTIQPNEACTFI 603
            ||..|.:|||.|:  |.:.|.:.              ||.:..|:   ||.|...:.||     .
Mouse   569 FLPQVFSKLFSFV--TFESVGESKAPRTRAVRNVRRHACSSINKM---CRDYPDLVLPN-----F 623

  Fly   604 DEILTTMSSIICD---LQPQQVHTFYEAVGYMISAQVDQVQQDVLIERYMQLPNQVW-DDIISRA 664
            |.:.:.:..::.:   |...:.....||:..:.:...|..:|.:.:|..|.....:| .:.:.||
Mouse   624 DMLYSHVKQLLSNELLLTQMEKCALMEALVLVSNQFKDYERQKLFLEELMAPVVNIWLSEEMCRA 688

  Fly   665 SKNVDFLKNMTAVKQLGSILKTNVAACK---ALGHAYVIQLGRIYLDMLNVYKITS-----ENII 721
            ..::|     :.:..:|:.||:...|.:   .|..|   ::......:|.|.:.||     |...
Mouse   689 LSDID-----SFIAYVGADLKSCDPAVEDPCGLNRA---RMSFCVYSILGVMRRTSWPSDLEEAK 745

  Fly   722 QAIEVNGVNVNNQPLIKTMHVVKKETLNLISEWVSRSNDNQLVMDNFIPPLLDAILLDYQRCKVP 786
            ....|.|...:..|:.:          |..:|.:.|..||.|.:
Mouse   746 AGGFVVGYTPSGNPIFR----------NPCTEQILRLLDNLLAL--------------------- 779

  Fly   787 SAREPKVLSAMAIIVHKLRQHITNEVPKIFDAV---FECTLDMINK-------------NFEDFP 835
                             :|.|.|...|::...:   |...||::..             .|.|.|
Mouse   780 -----------------VRTHNTLYTPEMLTKMAEPFTKALDIVESEKTAILGLPQPLLEFNDHP 827

  Fly   836 QHRLS------FYELLQAVNAHCFKAFLNIPPAQFKLVFDSVVWAFKHTMRNVADMGLNILFKML 894
            .:|.:      |:.:|.   .:|:.......|            :.:.....|.|:...:|....
Mouse   828 VYRTTLERMQRFFGILY---ENCYHILGKAGP------------SMQQDFYTVEDLASQLLGSAF 877

  Fly   895 QNLDQHPG-----------------AAQSFYQTYFTDILMQIFSVVTDTSHTAGLPNHAIILAYM 942
            .||:..|.                 .....|:|..:.||..:|:.:           | :.|:..
Mouse   878 VNLNNIPDFRLRSMLRVFVKPLVLFCPSEHYETLISPILGPLFTYL-----------H-MRLSQK 930

  Fly   943 FSLVENRKITVNLGPI----PDNMIFIQEYVASLL 973
            :.::..|.|......|    |::...::|.:..:|
Mouse   931 WHVINQRSILCGEDEIAEDNPESQEMLEEQLVRML 965

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.