Protein Alignment emb and crm1

DIOPT Version :10

• Sequence 1: NP_723391.2
• Gene: emb / 34167
• FlyBaseID: FBgn0020497
• Length: 1063
• Species: Drosophila melanogaster
• Sequence 2: NP_001342911.1
• Gene: crm1 / 3361487
• PomBaseID: SPAC1805.17
• Length: 1078
• Species: Schizosaccharomyces pombe
• Alignment Length: 1077
• Identity: 526/1077 - (48%)
• Similarity: 744/1077 - (69%)
• Gaps: 30/1077 - (2%)

  Fly    13 LLDFSQKLDINLLDKIVEVVYTAQGEQLRLAQSILTTLKEHPEAWTRVDSILEYSQNQRTKFYAL 77
            :|.|.::||:.|||::|:..|...|.:.:.||.:||..:.||:||::..||||.|:..:||:.||
pombe     4 ILAFDRELDVALLDRVVQTFYQGVGAEQQQAQQVLTQFQAHPDAWSQAYSILEKSEYPQTKYIAL 68

  Fly    78 QILEEVIKTRWKVLPRNQCEGIKKYVVSLIIKTSSDPIVMEQNKVYLNKLNMILVHILKREWPRN 142
            .:|:::|.||||:||:.|..||:.|:|:::||.|||..|::|.|.:||||::.||.|||:|||.|
pombe    69 SVLDKLITTRWKMLPKEQRLGIRNYIVAVMIKNSSDETVLQQQKTFLNKLDLTLVQILKQEWPHN 133

  Fly   143 WETFISDIVGASKTNESLCMNNMVILKNLSEEVFDFSQGQITQTKAKHLKDTMCSEFSQIFTLCS 207
            |..||.:||.|||||.|||.|||::|:.||||:||:|..|:||.|.|:||:.||.||::||.|||
pombe   134 WPNFIPEIVQASKTNLSLCENNMIVLRLLSEEIFDYSAEQMTQLKTKNLKNQMCGEFAEIFQLCS 198

  Fly   208 FVLENSMNAALIHVTLETLLRFLNWIPLGYIFETQQIETLIFKFLSVPMFRNVTLKCLSEIAGLT 272
            .:||.:...:||..||.|||||||||||||||||..:|.:..:||:||.|||||::||:|||.||
pombe   199 QILERAQKPSLIKATLGTLLRFLNWIPLGYIFETNIVELITNRFLNVPDFRNVTIECLTEIASLT 263

  Fly   273 A-ANYDENFATLFKDTMVQLEQIVGQNMNMNHVFKHGSDTEQELVLNLAMFLCTFLKEHGKLVED 336
            : ..|::.|.|:|...|..:..::....:....::..|..||:.:.|||:|||.|...|.:.:|:
pombe   264 SQPQYNDKFVTMFNLVMTSVNSMLPLQTDFREAYEESSTNEQDFIQNLALFLCAFFSSHLRPLEN 328

  Fly   337 AKYVDYLNQALMYLVMISEVEDVEVFKICLEYWNSLVEDLYN-------SEFFHPTLESTKRQQV 394
            .:..:.|..|..||:.||.:.:.|:||||||||:.||..||.       || .:|.|..:....:
pombe   329 PENQEVLLNAHSYLLNISRINEREIFKICLEYWSKLVAQLYEEMQQIPMSE-MNPLLNLSSPTSL 392

  Fly   395 YP-----------RRRFYAPILSKVRFIMISRMAKPEEVLVVENENGEVVREFMKDTNSINLYKN 448
            ..           |:..|..|||.:|.:||..|.||||||:|||:.||:||||:|:|::|.|||:
pombe   393 ISSNPNMLANLPLRKHIYKDILSTLRLVMIENMVKPEEVLIVENDEGEIVREFVKETDTITLYKS 457

  Fly   449 MRETLVFLTHLDSVDTDRIMTLKLLNQVNGSEFSWKNLNTLCWAIGSISGAFCEEDEKRFLVTVI 513
            |||.||:|||||.|||:.:||.||...|.|:|:||:|||||||||||||||..||.||||||.||
pombe   458 MREVLVYLTHLDVVDTEIVMTEKLARIVVGTEWSWQNLNTLCWAIGSISGAMNEEMEKRFLVNVI 522

  Fly   514 KDLLGLCEQKKGKDNKAIIASNIMYVVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACD 578
            ||||||||.|:||||||::|||||||||||||||:|||||||||||||||||||.|:||||||||
pombe   523 KDLLGLCEMKRGKDNKAVVASNIMYVVGQYPRFLKAHWKFLKTVVNKLFEFMHEYHEGVQDMACD 587

  Fly   579 TFIKIAIKCRRYFVTIQPNEACTFIDEILTTMSSIICDLQPQQVHTFYEAVGYMISAQVDQVQQD 643
            ||||||.||||:||..|..|...||:||:..::....||.|||.||||||.|||||||..:..|:
pombe   588 TFIKIAQKCRRHFVAQQLGETEPFINEIIRNLAKTTEDLTPQQTHTFYEACGYMISAQPQKHLQE 652

  Fly   644 VLIERYMQLPNQVWDDIISRASKNVDFLKNMTAVKQLGSILKTNVAACKALGHAYVIQLGRIYLD 708
            .||...|.||||.|::|:::|::|...|.:...||.|.::||||||||.::|..:..|:.:.|:|
pombe   653 RLIFDLMALPNQAWENIVAQAAQNAQVLGDPQTVKILANVLKTNVAACTSIGSGFYPQIAKNYVD 717

  Fly   709 MLNVYKITSENIIQAIEVNGVNVNNQPLIKTMHVVKKETLNLISEWVSRSNDNQLVMDNFIPPLL 773
            ||.:||..|..|.:.:...|......|.::.:..:|||.|.|:..::||:.|.:||.:..||.|.
pombe   718 MLGLYKAVSGLISEVVAAQGNIATKTPHVRGLRTIKKEILKLVDAYISRAEDLELVGNTLIPALF 782

  Fly   774 DAILLDYQRCKVPSAREPKVLSAMAIIVHKLRQHITNEVPKIFDAVFECTLDMINKNFEDFPQHR 838
            :|:||||.: .||.||:.:||:.:..||::|.:.:|:::|.:.||||.|||:||:|:|.::|:||
pombe   783 EAVLLDYLQ-NVPDARDAEVLNLITTIVNQLSELLTDKIPLVLDAVFGCTLEMISKDFSEYPEHR 846

  Fly   839 LSFYELLQAVNAHCFKAFLNIPPAQFKLVFDSVVWAFKHTMRNVADMGLNILFKMLQNL-DQHPG 902
            .:|::||:|:|.:||.|.||||..|||||.:|:||:|||..|::.:.|||||.:::.|: ...|.
pombe   847 AAFFQLLRAINLNCFPALLNIPAPQFKLVINSIVWSFKHVSRDIQETGLNILLELINNMASMGPD 911

  Fly   903 AAQSFYQTYFTDILMQIFSVVTDTSHTAGLPNHAIILAYMFSLVENRKITVNL---GPIP---DN 961
            .:.:|:|||:..:|..|..|:||:.|.:|....::|||.:|.|||:.:|||.|   ...|   :|
pombe   912 VSNAFFQTYYISLLQDILYVLTDSDHKSGFKLQSLILARLFYLVESNQITVPLYDPSQFPQEMNN 976

  Fly   962 MIFIQEYVASLLKSAFTHLSDNQVKVFVTGLFNLDENVQAFKEHLRDFLIQIREATGEDDSDLYL 1026
            .:|:::|:.:||.:||.||...|::.||..:..|:::...||..|||||||::| .|.|:::|||
pombe   977 QLFLRQYIMNLLVTAFPHLQPIQIQEFVQTVLALNQDSIKFKLALRDFLIQLKE-FGGDNAELYL 1040

  Fly  1027 EEREAALAEEQSNKHQMQRNIPGMLNPHELPEDMQDE 1063
            ||:|..||.:|..:.:....:|||:.|.::| .|::|
pombe  1041 EEKEQELAAQQKAQLEKAMTVPGMIKPVDMP-TMEEE 1076

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
emb	NP_723391.2	CRM1	13..1023	CDD:227432	510/1035 (49%)
crm1	NP_001342911.1	CRM1	1..1052	CDD:227432	518/1050 (49%)