Protein Alignment emb and xpo1

DIOPT Version :9

• Sequence 1: NP_001303316.1
• Gene: emb / 34167
• FlyBaseID: FBgn0020497
• Length: 1063
• Species: Drosophila melanogaster
• Sequence 2: XP_002939551.2
• Gene: xpo1 / 100380168
• XenbaseID: XB-GENE-993240
• Length: 1071
• Species: Xenopus tropicalis
• Alignment Length: 1068
• Identity: 756/1068 - (70%)
• Similarity: 888/1068 - (83%)
• Gaps: 10/1068 - (0%)

  Fly     3 TMLTSDEAGKLLDFSQKLDINLLDKIVEVVYTAQGEQLRLAQSILTTLKEHPEAWTRVDSILEYS 67
            |||....|.:||||||||||||||.:|..:|..:|.|.|:||.:||.|||||:||||||:|||:|
 Frog     6 TMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAWTRVDTILEFS 70

  Fly    68 QNQRTKFYALQILEEVIKTRWKVLPRNQCEGIKKYVVSLIIKTSSDPIVMEQNKVYLNKLNMILV 132
            ||..||:|.|||||.|||||||:||||||||||||||.||||||||...:|:.|||:.|||||||
 Frog    71 QNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDATCVEKEKVYIGKLNMILV 135

  Fly   133 HILKREWPRNWETFISDIVGASKTNESLCMNNMVILKNLSEEVFDFSQGQITQTKAKHLKDTMCS 197
            .|||:|||::|.||||||||||:|:||||.|||||||.|||||||||.|||||.|||||||:||:
 Frog   136 QILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFDFSSGQITQVKAKHLKDSMCN 200

  Fly   198 EFSQIFTLCSFVLENSMNAALIHVTLETLLRFLNWIPLGYIFETQQIETLIFKFLSVPMFRNVTL 262
            ||||||.||.||:|||.||.|:|.||||||||||||||||||||:.|.|||:|||:|||||||:|
 Frog   201 EFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGYIFETKLISTLIYKFLNVPMFRNVSL 265

  Fly   263 KCLSEIAGLTAANYDENFATLFKDTMVQLEQIVGQNMNMNHVFKHGSDTEQELVLNLAMFLCTFL 327
            |||:||||::.:.|:|.|.|||..||:||:|::..|.|:...:.:|.|.||..:.||::||||||
 Frog   266 KCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPLNTNIRLAYSNGKDDEQNFIQNLSLFLCTFL 330

  Fly   328 KEHGKLVEDAKYV-DYLNQALMYLVMISEVEDVEVFKICLEYWNSLVEDLYNSEFF----HPTLE 387
            ||||:|:|....: :.|.:||.|::::||||:.|:|||||||||.|..:||....|    .|.|.
 Frog   331 KEHGQLIEKRLNLRETLMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESPFSTSASPLLS 395

  Fly   388 STKRQQVYPRRRFYAPILSKVRFIMISRMAKPEEVLVVENENGEVVREFMKDTNSINLYKNMRET 452
            .::...|.|||:.|.|:|||||.:|:||||||||||||||:.|||||||||||:|||||||||||
 Frog   396 GSQHFDVPPRRQLYLPVLSKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRET 460

  Fly   453 LVFLTHLDSVDTDRIMTLKLLNQVNGSEFSWKNLNTLCWAIGSISGAFCEEDEKRFLVTVIKDLL 517
            ||:|||||..||:||||.||.|||||:|:||||||||||||||||||..||||||||||||||||
 Frog   461 LVYLTHLDYADTERIMTEKLHNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLL 525

  Fly   518 GLCEQKKGKDNKAIIASNIMYVVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIK 582
            ||||||:||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||
 Frog   526 GLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIK 590

  Fly   583 IAIKCRRYFVTIQPNEACTFIDEILTTMSSIICDLQPQQVHTFYEAVGYMISAQVDQVQQDVLIE 647
            ||.||||:||.:|..|...||||||..:::|||||||||||||||||||||.||.||..|:.|||
 Frog   591 IAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIE 655

  Fly   648 RYMQLPNQVWDDIISRASKNVDFLKNMTAVKQLGSILKTNVAACKALGHAYVIQLGRIYLDMLNV 712
            :||.|||||||.||.:|:||||.||:...||||||||||||.||||:||.:||||||||||||||
 Frog   656 KYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNV 720

  Fly   713 YKITSENIIQAIEVNGVNVNNQPLIKTMHVVKKETLNLISEWVSRSNDNQLVMDNFIPPLLDAIL 777
            ||..||||..||:.||..|..||||::|..||:|||.|||.|||||:|.|:|.:||:||||||:|
 Frog   721 YKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSSDPQMVAENFVPPLLDAVL 785

  Fly   778 LDYQRCKVPSAREPKVLSAMAIIVHKLRQHITNEVPKIFDAVFECTLDMINKNFEDFPQHRLSFY 842
            :|||| .||:||||:|||.||.||:||..|||.|:|:||||||||||:||||:||::|:||.:|:
 Frog   786 IDYQR-NVPAAREPEVLSTMATIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEEYPEHRTNFF 849

  Fly   843 ELLQAVNAHCFKAFLNIPPAQFKLVFDSVVWAFKHTMRNVADMGLNILFKMLQNLDQHPGAAQSF 907
            .||||||:|||.|||.|||||||||.||::||||||||||||.||.||:.:|||:.|...|||||
 Frog   850 LLLQAVNSHCFPAFLAIPPAQFKLVLDSIIWAFKHTMRNVADTGLQILYTLLQNVAQEEAAAQSF 914

  Fly   908 YQTYFTDILMQIFSVVTDTSHTAGLPNHAIILAYMFSLVENRKITVNL---GPIPDNMIFIQEYV 969
            |||||.|||..||||||||||||||..||.||||||:|||..||:..|   .|: .|.:||||||
 Frog   915 YQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKISTPLNQASPL-SNQLFIQEYV 978

  Fly   970 ASLLKSAFTHLSDNQVKVFVTGLFNLDENVQAFKEHLRDFLIQIREATGEDDSDLYLEEREAALA 1034
            |:||||||.||.|.|||:||||||:|::::.||||||||||:||:|..|||.|||:|||||::|.
 Frog   979 ANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLVQIKEYAGEDTSDLFLEERESSLR 1043

  Fly  1035 EEQSNKHQMQRNIPGMLNPHELPEDMQD 1062
            :.|..||::|.::||:|||||:||:|.|
 Frog  1044 QAQEEKHKLQMSVPGILNPHEIPEEMCD 1071

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
emb	NP_001303316.1	CRM1	13..1023	CDD:227432	728/1017 (72%)
		IBN_N	43..109	CDD:197981	52/65 (80%)
		Xpo1	120..265	CDD:285575	115/144 (80%)
		CRM1_C	701..1015	CDD:285920	221/316 (70%)
xpo1	XP_002939551.2	CRM1	15..1044	CDD:227432	737/1030 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	284	1.000	Domainoid score	I1612
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2554
Inparanoid	1	1.050	1438	1.000	Inparanoid score	I122
OMA	1	1.010	-	-		QHG53807
OrthoDB	1	1.010	-	-		D132850at2759
OrthoFinder	1	1.000	-	-		FOG0003578
OrthoInspector	1	1.000	-	-		oto104866
Panther	1	1.100	-	-	LDO	PTHR11223
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R13754
SonicParanoid	1	1.000	-	-		X2450
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110