Protein Alignment fy and FUZ

DIOPT Version :9

• Sequence 1: NP_001260250.1
• Gene: fy / 34166
• FlyBaseID: FBgn0001084
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_001339191.1
• Gene: FUZ / 80199
• HGNCID: 26219
• Length: 419
• Species: Homo sapiens
• Alignment Length: 440
• Identity: 128/440 - (29%)
• Similarity: 210/440 - (47%)
• Gaps: 69/440 - (15%)

  Fly     2 SIYLLCLTTNGGLPVFTR-KKGEC---ENLPFSTVASLNGFHMFFKSLGIQLEATTTSKQQPIQN 62
            :::||||..:.|:|:|.| .:|..   :.||||.:.||||.|||.::|.:||.:..|
Human     9 TVHLLCLAASSGVPLFCRSSRGGAPARQQLPFSVIGSLNGVHMFGQNLEVQLSSART-------- 65

  Fly    63 QAPADAEEWTYIWRD-RESITLIVCGCGVG-SEQLLQTLADLVFGAIGMFITRAAEMAHATLLDR 125
                  |..|.:|:. .:||||||....|| ||..|:.|..:||||: :.:....|:.:...::|
Human    66 ------ENTTVVWKSFHDSITLIVLSSEVGISELRLERLLQMVFGAM-VLLVGLEELTNIRNVER 123

  Fly   126 LKKDAKKYVPIVDAILEAACAGTQLLG----YTDCLLAAENAQLLQCLNEFSGHCGSLFCCLVVG 186
            ||||.:....::|:.|    ..::|:|    ..||::..|.:.|.:.|:.|:...|:.|..|||.
Human   124 LKKDLRASYCLIDSFL----GDSELIGDLTQCVDCVIPPEGSLLQEALSGFAEAAGTTFVSLVVS 184

  Fly   187 HRIAVATEGWWDLDTRDRELLLFLLNS-SSTMQHDVPVYLPVKSPHIAYRFVSIPVASNSALCVL 250
            .|:..||||||.|.|.:..||.:|:.| ......|.|||||..||.:.:|.:::.:..:..||:|
Human   185 GRVVAATEGWWRLGTPEAVLLPWLVGSLPPQTARDYPVYLPHGSPTVPHRLLTLTLLPSLELCLL 249

  Fly   251 CGAENASFRELHAHAMSAYRNEGNLLAAAERCV---PRSLPEHLEIDGNVLAIILINRHTRKSLF 312
            || .:....:|:...:..:...  ||.....|:   ||:||....:..::|.::|::...::.||
Human   250 CG-PSPPLSQLYPQLLERWWQP--LLDPLRACLPLGPRALPSGFPLHTDILGLLLLHLELKRCLF 311

  Fly   313 TRNLNQSASVKRIIVGDL------QRLDILKKFFDQTMDAVHQFETQSSSNKTTLVDQYSCSDYH 371
            |        |:.:  ||.      ||..:|:.|:  |:.....|..:....:.|..:.|......
Human   312 T--------VEPL--GDKAEPSPEQRRRLLRNFY--TLVTSTHFPPEPGPPEKTEDEVYQAQLPR 364

  Fly   372 KCYAHMD-------------ELG-NVIFLLFVAAVPSHAMRFLA-QRIHA 406
            .||..:.             :|| ..:.||.....|:|.:|.|| ..:||
Human   365 ACYLVLGTEEPGTGVRLVALQLGLRRLLLLLSPQSPTHGLRSLATHTLHA 414

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156408
Domainoid	1	1.000	152	1.000	Domainoid score	I4345
eggNOG	1	0.900	-	-		E1_28P1D
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11840
Inparanoid	1	1.050	152	1.000	Inparanoid score	I4363
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52234
OrthoDB	1	1.010	-	-		D317877at33208
OrthoFinder	1	1.000	-	-		FOG0007236
OrthoInspector	1	1.000	-	-		oto89963
orthoMCL	1	0.900	-	-		OOG6_108500
Panther	1	1.100	-	-	LDO	PTHR13559
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7548
SonicParanoid	1	1.000	-	-		X5339
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800