Protein Alignment SLC5A11 and smvt-1

DIOPT Version :10

• Sequence 1: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001360058.2
• Gene: smvt-1 / 186132
• WormBaseID: WBGene00018716
• Length: 565
• Species: Caenorhabditis elegans
• Alignment Length: 601
• Identity: 170/601 - (28%)
• Similarity: 293/601 - (48%)
• Gaps: 71/601 - (11%)

  Fly    18 DYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDFGSEKMSEYLLGSRNLKV 82
            ||...|..::..::    :|.||..|.:.||                   :.:...::||| :.|
 Worm     5 DYVTLLTCLISISA----YGFIKSRKTENEE-------------------QSVHATMVGSR-VSV 45

  Fly    83 FPVAMSLIASYISGVTILGTTSEI-YNYGTQYWFIAIAIMLQGIAVSYVYIPVFSALQVGSSYEY 146
            :...:|:.:.:||.:::||..:|| |..|...||..:.::...| |::|::||...|::.:.|||
 Worm    46 WSATLSVCSGFISSISLLGFPAEIYYQGGMMLWFAPMYVISFPI-VAFVFLPVLYRLKLTTIYEY 109

  Fly   147 LEMRFHSVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAVVIVVVCVFYTFVGGIK 211
            .|.||....|.:.:.:|.:..||:....:|.|::|:..::.|.:.|..::..|:..||..|||:|
 Worm   110 FERRFDYKCRFVTTSLFCVQMILYNSVALYAPSLAIASITNIPITVSILITAVLSAFYISVGGVK 174

  Fly   212 AVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDDAAKGGRLIFNNTNPSPYVRHTVWSVLIG 276
            |.:||.|.|:|::||::..: |..::....::.::.....|.|.|.|:...:|.:||:|||:|||
 Worm   175 AGIHTSAIQMLLIFLTMTFI-ISISLREMSIHDVYTSVVHGKRFILNDFRINPTIRHSVWSLLIG 238

  Fly   277 GFSYWTSFNAVNQTMVQRYMSLPSLKKAR----ASMAIFTIGVAAFVSVCCYVGLLIYEMYKDCD 337
            |.....:..|.||..:||||::.:||.|:    .::...||.:.::||    ||.|||..||||.
 Worm   239 GTGNILALFAANQLSIQRYMAMDTLKSAQKVVLLNIVCNTIILVSYVS----VGFLIYAHYKDCH 299

  Fly   338 PLSAGLITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILED---IVRG 399
            |    .|.:.::|||.||:.......|..|||.|.::.|.:|:||....:.|.:::.|   :.|.
 Worm   300 P----QIGNANELLPRFVMDVTSKYPGSVGLFAAAVYSAGISTLSASFTAVSSIVINDVWKVYRE 360

  Fly   400 CFKMQP-----SERASTILVKSTVIVLGFVALSLVFVLEQL-SGILSICTSMTAIAAGTTFGLFT 458
            ..||.|     .:.|..||    .|||.|:::.:.|:...| |.||.:...:.....|...|.|.
 Worm   361 RRKMAPLRNDQVQNAMRIL----PIVLSFISIFVAFLCSMLQSIILQVSFIVFGAGGGPVLGSFV 421

  Fly   459 LGMLVPWANTVGTAVGGIASALLAGWISFGT------QFTIAAGELNSQKLPVSVEGCVGNVTLR 517
            :|:.||........||.|.|.::...||.|:      ...:..|:.::|.|....|..:|.||..
 Worm   422 VGLFVPRVKEKAALVGLIGSIIVCFSISIGSVLVKVKPVALELGQCSNQTLTYFDESFIGAVTST 486

  Fly   518 ENIWVDEEQVFPLYRLSYHWINPIGVAT----VIVVGALVSLVTKPTNMKTLDPDLISPVIHRFL 578
            ..::..|.    ::.:||.:.:.|.|.|    .||:..|..|.:...|...:..:|:||::
 Worm   487 PLVFGLER----IFAISYQYYSIIAVVTNVALSIVMQKLFELCSLTANHLPVSHELVSPLL---- 543

  Fly   579 PKECFSGRNLHAQAHK 594
             ....|.|:...:||:
 Worm   544 -TYSSSKRDPELEAHR 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	161/561 (29%)
smvt-1	NP_001360058.2	SLC5sbd_NIS-SMVT	5..521	CDD:271383	160/557 (29%)