Protein Alignment Wwox and ENV9

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_014889.3
• Gene: ENV9 / 854420
• SGDID: S000005772
• Length: 330
• Species: Saccharomyces cerevisiae
• Alignment Length: 331
• Identity: 90/331 - (27%)
• Similarity: 137/331 - (41%)
• Gaps: 80/331 - (24%)

  Fly   122 RTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRC---------- 176
            :.|::||.|.|||:.|...|..||..:....||......||:.|..|   |:.||
Yeast    17 KIAVVTGGNTGIGWYTVLHLYLHGFVVYICGRNSHKISKAIQEILAE---AKKRCHEDDDGSSPG 78

  Fly   177 -------------RFAALDLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTF 228
                         .:..|||:.|:.|:|...:|.:...|||.|:.|||:.|:|...|.||.|...
Yeast    79 AGPGPSIQRLGSLHYIHLDLTDLKCVERAALKILKLEDHIDVLVNNAGIMAVPLEMTKDGFEVQL 143

  Fly   229 QVSHLSHFYLTLQLETLFDY-KTRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSM------- 285
            |.:::|||..|::|..|..: :.|||.|||..             |||.   ..||.:
Yeast   144 QTNYISHFIFTMRLLPLLRHCRGRIISLSSIG-------------HHLE---FMYWKLSKTWDYK 192

  Fly   286 -------MAYNNAKLCNVLFAQELAQRWKQRGISVFSLHPGNMVSSDLSRNYW--------FYRL 335
                   ..|..:|...:...:.||.::..  :...|:|||.:::::|. :||        |:.|
Yeast   193 PNMLFTWFRYAMSKTALIQCTKMLAIKYPD--VLCLSVHPGLVMNTNLF-SYWTRLPIVGIFFWL 254

  Fly   336 LFAIVR-PFTKSLQQAAATSIYCATANELTGLSGLYFNNCFFCEPSKLSKSA--------ALQQQ 391
            ||.:|. .|..|.:|.:..|:.||..   ..||....|..:|....|.|||:        |....
Yeast   255 LFQVVGFFFGVSNEQGSLASLKCALD---PNLSVEKDNGKYFTTGGKESKSSYVSNNVDEAASTW 316

  Fly   392 LWKLSE 397
            :|.:.:
Yeast   317 IWTVHQ 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	90/331 (27%)
ENV9	NP_014889.3	Rossmann-fold NAD(P)(+)-binding proteins	17..318	CDD:473865	89/325 (27%)