Protein Alignment Wwox and FEY

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_194506.4
• Gene: FEY / 828890
• AraportID: AT4G27760
• Length: 376
• Species: Arabidopsis thaliana
• Alignment Length: 403
• Identity: 107/403 - (26%)
• Similarity: 177/403 - (43%)
• Gaps: 71/403 - (17%)

  Fly    35 KTSQWTHPRTGRSKRITG--ELPLGWEKYYDEQGKRFMFLNKETQQRTNVDPRLAFAVEEPTQNV 97
            :|:....|...:.|:..|  |...||...:.|    .:|      ||..     |..:|.|
plant     4 ETTSSPSPAPAKKKQNLGWMEWMRGWSSVFGE----ILF------QRIT-----ASHLENP---- 49

  Fly    98 AQVRQRFDSCSTALQVLHGKDLHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAI 162
                         |.:....||   |.::||:..|||.||||.||..|..::.|.||..:|:..|
plant    50 -------------LPLPSVNDL---TCVVTGSTSGIGRETARQLAEAGAHVVMAVRNTKAAQELI 98

  Fly   163 ERIAQERPAARSRCRFAA--LDLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTR--TVDG 223
            .:...|...........|  :||.||.||.||.|.....:..:..||.|||:||:...:  :.:|
plant    99 LQWQNEWSGKGLPLNIEAMEIDLLSLDSVARFAEAFNARLGPLHVLINNAGMFAMGEAQKFSEEG 163

  Fly   224 LETTFQVSHLSHFYLTLQL--ETLFDYKTRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMM 286
            .|...||:||:...|::.|  ..:....:|||.::|..|....:..:::   ::.....||.|::
plant   164 YEQHMQVNHLAPALLSVLLLPSLIRGSPSRIINVNSVMHSVGFVDPDDM---NVVSGRRKYSSLI 225

  Fly   287 AYNNAKLCNVLFAQELAQRWK-QRGISVFSLHPG---NMVSSDLSRNYWFYRLLFAIVRPFTKSL 347
            .|:::||..::|:..|.::.. :.|:||..|.||   ..|:.||||   ..:.|:|::..|..|.
plant   226 GYSSSKLAQIMFSSILFKKLPLETGVSVVCLSPGVVLTNVARDLSR---ILQALYAVIPYFIFSP 287

  Fly   348 QQAAATSIYCATANELTGLSGLYFNN----CFF----CEPSKLSKSA---ALQQQLWKLSENLIA 401
            |:...:|::.||..::........|:    |.|    |.|:..|:.|   ...|::||.:..|:.
plant   288 QEGCRSSLFSATDPQIPEYWETLKNDDWPVCPFISQDCRPANPSEEAHNTETAQRVWKKTLELVG 352

  Fly   402 -------ELVEQE 407
                   :|:|.|
plant   353 LPLDAVEKLIEGE 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736	1/7 (14%)
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	87/308 (28%)
FEY	NP_194506.4	Rossmann-fold NAD(P)(+)-binding proteins	61..344	CDD:473865	83/288 (29%)