Protein Alignment Wwox and si:dkey-174n20.1

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001076385.2
• Gene: si:dkey-174n20.1 / 796174
• ZFINID: ZDB-GENE-030131-7890
• Length: 308
• Species: Danio rerio
• Alignment Length: 300
• Identity: 99/300 - (33%)
• Similarity: 157/300 - (52%)
• Gaps: 40/300 - (13%)

  Fly   117 KDLHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARS---RCRF 178
            |.|.|:|.||||.|.|||.|||.:||..|..:|.|||:...|..|:..|     .|||   ....
Zfish    30 KRLDGKTVLITGGNSGIGKETAVALAMRGARVIIACRDEEKARKAVREI-----KARSHNMNVLH 89

  Fly   179 AALDLSSLRSVQRFVEEIKQSVSHIDYLILNAGV-FALPYTRTVDGLETTFQVSHLSHFYLT-LQ 241
            ..:||:::||::.|.:...|....:|.||.|||: ..|.:|.  |.....|.|:||.||.|| |.
Zfish    90 MEVDLANMRSIREFSKTFLQKEKRLDILINNAGMPGVLDWTD--DNFSMCFGVNHLGHFLLTNLL 152

  Fly   242 LETLFDYK-TRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMAYNNAKLCNVLFAQELAQR 305
            |..|.:.. :|:|.|:..|:::..|..::|. ::|.|       ...|..:||.|:.|.||||:.
Zfish   153 LPRLKESSPSRVINLTCSSYKYQKLNFQDLN-YNLFP-------FFTYCRSKLANIYFTQELARM 209

  Fly   306 WKQRGISVFSLHPGNMVSSDLSRNYW------FYRLLFAIVR-PFTKSLQQAAATSIYCATANEL 363
            .:.:|::.:::|||.:      |:.|      .|::|..:|. .|..|.:..|.|.:|||.::|:
Zfish   210 MEGKGVTAYAVHPGYV------RSRWTCHFSVLYQILAQVVMFMFFVSCEAGAQTVVYCAVSDEV 268

  Fly   364 TGLSGLYFNNCFFCEPSKL---SKSAALQQQLWKLSENLI 400
            ...:|.||.:   |.|:.|   ::.:.:.::||:.||.|:
Zfish   269 LPRNGGYFTD---CRPAPLKAFARDSGVAKKLWEASERLV 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	97/295 (33%)
si:dkey-174n20.1	NP_001076385.2	Rossmann-fold NAD(P)(+)-binding proteins	34..301	CDD:473865	94/290 (32%)