Protein Alignment Wwox and hsd17b7

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001070796.1
• Gene: hsd17b7 / 768185
• ZFINID: ZDB-GENE-061013-378
• Length: 340
• Species: Danio rerio
• Alignment Length: 345
• Identity: 88/345 - (25%)
• Similarity: 141/345 - (40%)
• Gaps: 86/345 - (24%)

  Fly   122 RTALITGANCGIGYETARSLAHHGC--EIIFACRNRSSAEAAIERIAQERPAARSRCRFAALDLS 184
            :..|:||||.|||......|.:...  |:..||||...||||.:.:....|.|  |.....||:.
Zfish     3 KVVLVTGANSGIGLALCERLLNEDAQIELCLACRNMQRAEAARKALLVSHPQA--RVSLLHLDVG 65

  Fly   185 SLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVD--------------------------- 222
            ::.||.:..||.|:..:.:|||.||||:...|   |||
Zfish    66 NMHSVVKGAEEFKKKFNRLDYLYLNAGIMPNP---TVDHVAFYRGLFSRNAIKMLTTGEGILTQE 127

  Fly   223 ------GLETTFQVSHLSHFYLTLQLETLF---DYKTRIIVLSSESHRFANLPVENLAVHHLSPP 278
                  ||:..|..:...||.|..:||.|.   ::.:.:|..||.:.:.::..:|:  |.|.:.|
Zfish   128 DKVTPIGLQEVFATNLFGHFLLVKELEPLLCQTEHNSLVIWTSSSNAQRSSFNLED--VQHKNGP 190

  Fly   279 PEKYWSMMAYNNAKLCNVLFAQELAQRWKQRGISVFSLHPG----NMVSSDLSRNYW--FYRLLF 337
                   :.|:::|..:.|.:..|.:.:..:|:....:.||    |:....|...:|  ...:||
Zfish   191 -------LPYSSSKYASDLLSLALNRHYNSQGMFSSVICPGLVMTNLTYGILPSLFWTIIMPILF 248

  Fly   338 AIVRPFTKSLQQA---AATSIY------------CATANELTGLSGLYFNNCFFCEPSKLSKSAA 387
             ::|.||.|...:   .|.::|            .|..:.||  |||..|   :..|||:....
Zfish   249 -LIRIFTNSFTLSPYNGAEALYWLFKQKPESLDPMAKYHSLT--SGLGNN---YTRPSKMDLDE- 306

  Fly   388 LQQQLWKLSENLIAELVEQE 407
                  .:||....:|:|.|
Zfish   307 ------NMSEAFYVKLLELE 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	85/338 (25%)
hsd17b7	NP_001070796.1	3KS_SDR_c	2..280	CDD:187645	73/291 (25%)