Protein Alignment Wwox and hsd17b7

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001016209.1
• Gene: hsd17b7 / 548963
• XenbaseID: XB-GENE-976825
• Length: 334
• Species: Xenopus tropicalis
• Alignment Length: 339
• Identity: 80/339 - (23%)
• Similarity: 139/339 - (41%)
• Gaps: 72/339 - (21%)

  Fly   122 RTALITGANCGIGYETARSLAHHGCEI--IFACRNRSSAEAAIERIAQERPAARSRCRFAALDLS 184
            :..::||||.|||:.....|..:..:|  ...|||...||||...:....|.|  ......:|:.
 Frog     3 KVVVVTGANSGIGFALCERLLSYDDQIRLCLGCRNLQRAEAARTALLSSHPTA--DVSVLLVDVG 65

  Fly   185 SLRSVQRFVEEIKQSVSHIDYLILNAGVFALP-----------YTRTV----------------- 221
            .:.||.|..:|:|:....:|||.||||:...|           ::|.|
 Frog    66 KVTSVVRAAKELKERYKKVDYLYLNAGIMPNPQLSFRAFIKGLFSRNVINMFATAEGILTQKDRI 130

  Fly   222 --DGLETTFQVSHLSHFYLTLQLETLF---DYKTRIIVLSSESHRFANLPVENLAVHHLSPPPEK 281
              |||:..|:.:...||.|..::|.|.   |..:::|..||.:.|.:...:.:.. |.....|
 Frog   131 TEDGLQEVFETNVFGHFMLIREIEPLLCHADSTSQLIWTSSSNARKSAFSLSDYQ-HSQGQEP-- 192

  Fly   282 YWSMMAYNNAKLCNVLFAQELAQRWKQRGISVFSLHPGNMVSSDLSRNY---WFYRLLFAI---V 340
                  |:::|....|.:..|.:::.::|:....:.|| :|.::|:...   :|:.|:..|   :
 Frog   193 ------YSSSKYATDLLSVALNKQYNKQGLYSSVVCPG-LVMTNLTYGIMPSFFWTLIMPIMWLI 250

  Fly   341 RPFTKSLQ------QAAATSIYCATANELTGLSGLY-----FNNCFFCEPSKLSKSAALQQQLWK 394
            |.||.|..      ..|...::...|..|..||..:     ..|.:.|    |||....:    |
 Frog   251 RVFTNSFTISPFNGAEALMWLFNQKAESLDPLSKYHSCTSGLGNNYVC----LSKMDVDE----K 307

  Fly   395 LSENLIAELVEQEQ 408
            ..:.|:.:::|.|:
 Frog   308 SGDLLLQKMLELEK 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	78/331 (24%)
hsd17b7	NP_001016209.1	3KS_SDR_c	2..280	CDD:187645	68/288 (24%)