Protein Alignment Wwox and si:ch211-107o10.3

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001186229.1
• Gene: si:ch211-107o10.3 / 407663
• ZFINID: ZDB-GENE-030131-4716
• Length: 327
• Species: Danio rerio
• Alignment Length: 291
• Identity: 103/291 - (35%)
• Similarity: 155/291 - (53%)
• Gaps: 22/291 - (7%)

  Fly   119 LHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAALDL 183
            |.|:|.||||.|.|||.|||..:|..|..:|.|||:.|.|..|.|.|  .:.:.........|||
Zfish    47 LDGKTVLITGGNTGIGKETAVDMAKRGARVILACRDMSRAHKAAEEI--RKRSGNENVTVKMLDL 109

  Fly   184 SSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYLTLQLETLF-- 246
            :||:||:..|::::||...:|.||.||||...|...|.:|.|....|:||.||.||..|..|.
Zfish   110 ASLQSVRDLVKDVQQSEQRLDILINNAGVMMCPKWHTDEGFEMQIGVNHLGHFLLTNLLLDLLKK 174

  Fly   247 DYKTRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMAYNNAKLCNVLFAQELAQRWKQRGI 311
            ...:||:.::|.:|....:...::.:      .:.|....:|..:||.||||.:|||.:.:..|:
Zfish   175 SAPSRIVNVASVAHERGKINFNDINM------DKDYDPYQSYYRSKLANVLFTRELAIKLRDTGV 233

  Fly   312 SVFSLHPGNMVSSDLSR----NYWFYRLLFAIVRP---FTKSLQQAAATSIYCATANELTGLSGL 369
            :.::|||| ::.::|.|    |.|  |.|  |:.|   |.|:..|.|.|:||||....|...|||
Zfish   234 TTYALHPG-VIRTELGRHVFSNLW--RKL--IILPFYFFFKNPWQGAQTTIYCAVDESLKHSSGL 293

  Fly   370 YFNNCFFCEPSKLSKSAALQQQLWKLSENLI 400
            |:::|...|.:...:.....::||.||.:::
Zfish   294 YYSDCAPKETAPQGRDDVAARRLWDLSASMV 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	102/289 (35%)
si:ch211-107o10.3	NP_001186229.1	Rossmann-fold NAD(P)(+)-binding proteins	49..320	CDD:473865	100/283 (35%)