Protein Alignment Wwox and Dhrs13

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001385697.1
• Gene: Dhrs13 / 303275
• RGDID: 1305508
• Length: 375
• Species: Rattus norvegicus
• Alignment Length: 293
• Identity: 108/293 - (36%)
• Similarity: 151/293 - (51%)
• Gaps: 28/293 - (9%)

  Fly   119 LHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAALDL 183
            |.||||::||||.|||..||..||..|..::.|||:|...|||...:.||  :..:...|.||||
  Rat    34 LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQE--SGNNEVIFMALDL 96

  Fly   184 SSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYLT-LQLETLFD 247
            :||.|||.|......|...:|.||.|||:.:...||....|  ..:|:|:..|.|| |.|..|..
  Rat    97 ASLTSVQAFATAFLSSEPRLDILIHNAGISSCGRTRETFNL--LLRVNHVGPFLLTHLLLPRLRS 159

  Fly   248 -YKTRIIVLSSESHRFANLPVENLAVHHLSPPPEKYW--SMMAYNNAKLCNVLFAQELAQRWKQR 309
             ..:|::::||.:||...|....|..      |...|  .:.||.::||.|||||:|||.:.:..
  Rat   160 CAPSRVVIVSSAAHRRGRLDFTRLDC------PVVGWQQELRAYADSKLANVLFARELATQLEGT 218

  Fly   310 GISVFSLHPGNMVSSDLSRNYWFYRLLFAIVRPFTKSL--------QQAAATSIYCATANELTGL 366
            |::.::.||| .|:|:|     |.|.|...:||..:.|        |..|.|.:|||....:..|
  Rat   219 GVTCYAAHPG-PVNSEL-----FLRHLPGWLRPILRPLAWLVLRAPQGGAQTPLYCALQEGIEPL 277

  Fly   367 SGLYFNNCFFCEPSKLSKSAALQQQLWKLSENL 399
            ||.||.||...|.|..::......:|||:::.|
  Rat   278 SGRYFANCHVEEVSAAARDDQAAHRLWKVTKKL 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	107/291 (37%)
Dhrs13	NP_001385697.1	retinol-DH_like_SDR_c_like	36..304	CDD:212492	103/283 (36%)