Protein Alignment Wwox and Wwox

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001402035.1
• Gene: Wwox / 292041
• RGDID: 1309927
• Length: 414
• Species: Rattus norvegicus
• Alignment Length: 406
• Identity: 204/406 - (50%)
• Similarity: 269/406 - (66%)
• Gaps: 14/406 - (3%)

  Fly     4 LPDTDSEDELPPGWEERATDDGTVCYVNQQGKTSQWTHPRTGRSKRITGELPLGWEKYYDEQGKR 68
            |.|||||||||||||||.|.||.|.|.|...:.:||.||:||:.||:.|:||.|||:..||.|:.
  Rat     9 LDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQV 73

  Fly    69 FM--FLNKETQQRTNVDPRLAFAVEE-PTQNVAQVRQRFDSCSTALQVLHGKDLHGRTALITGAN 130
            |.  .:||.|   |.:||||||.|:: ||:  ...|||:|..:||:::|.|:|..|:..|:||||
  Rat    74 FFVDHINKRT---TYLDPRLAFTVDDNPTK--PTTRQRYDGSTTAMEILQGRDFTGKVVLVTGAN 133

  Fly   131 CGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAALDLSSLRSVQRFVEE 195
            .|||:|||:|.|.||..:|.||||.|.|..|:.||.:|...|:...  ..|||:.|||||.|.|.
  Rat   134 SGIGFETAKSFALHGAHVILACRNMSRASEAVSRILEEWHKAKVEA--MTLDLAVLRSVQHFAEA 196

  Fly   196 IKQSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYLTLQLETLF--DYKTRIIVLSSE 258
            .|.....:..|:.|||.||||::.|.|||||||||:||.||||...|:.:.  ....|:||:|||
  Rat   197 FKAKNVPLHILVCNAGTFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSSE 261

  Fly   259 SHRFANLPVEN--LAVHHLSPPPEKYWSMMAYNNAKLCNVLFAQELAQRWKQRGISVFSLHPGNM 321
            ||||.::...:  |.:..||.....||:|:|||.:||||:||:.||.:....||::..:||||||
  Rat   262 SHRFTDINDSSGKLDLSRLSLSSSDYWAMLAYNRSKLCNILFSNELHRLLSPRGVTSNALHPGNM 326

  Fly   322 VSSDLSRNYWFYRLLFAIVRPFTKSLQQAAATSIYCATANELTGLSGLYFNNCFFCEPSKLSKSA 386
            :.|.:.||.|.|:|||.:.||||||:||.|||::|||.|.||.||.|:|||||..|.||:.:::.
  Rat   327 MFSAIHRNSWVYKLLFTLARPFTKSMQQGAATTVYCAVAPELEGLGGMYFNNCCRCLPSEEAQNE 391

  Fly   387 ALQQQLWKLSENLIAE 402
            ...:.||:|||.||.:
  Rat   392 ETARALWELSERLIQD 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736	17/29 (59%)
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	142/284 (50%)
Wwox	NP_001402035.1	WW	18..47	CDD:459800	16/28 (57%)
		WW	60..90	CDD:238122	13/31 (42%)
		human_WWOX_like_SDR_c-like	124..407	CDD:187669	142/286 (50%)