Protein Alignment Wwox and CG30495

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001260785.1
• Gene: CG30495 / 246651
• FlyBaseID: FBgn0050495
• Length: 331
• Species: Drosophila melanogaster
• Alignment Length: 294
• Identity: 99/294 - (33%)
• Similarity: 155/294 - (52%)
• Gaps: 25/294 - (8%)

  Fly   118 DLHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAALD 182
            |..|:.|::||.|.|:|.||...||..|..:..||||:...|.|...|.:|  ...|.......|
  Fly    42 DETGKVAIVTGGNTGLGKETVMELARRGATVYMACRNKEKVERARREIVKE--TGNSNVFSRECD 104

  Fly   183 LSSLRSVQRFVEEIK--QSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYLTLQLETL 245
            ||||.|:::|.|..|  |.|.||  ||.|||||..|:..|.:|.|....|:|:.||.||..|..:
  Fly   105 LSSLDSIRKFAENFKKEQRVLHI--LINNAGVFWEPHRLTKEGFEMHLGVNHIGHFLLTNLLLGV 167

  Fly   246 FDYK--TRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMAYNNAKLCNVLFAQELAQRWKQ 308
            .:..  :|::|::|.:|....:.|:::      ...:.|...:||..:||.|:||.:|||:|.:.
  Fly   168 LERSAPSRVVVVASRAHERGQIKVDDI------NSSDFYDEGVAYCQSKLANILFTRELAKRLEG 226

  Fly   309 RGISVFSLHPGNMVSSDLSRNYWFYRLLFA------IVRPF----TKSLQQAAATSIYCATANEL 363
            .|::|.:|:|| :..::::||..|::..||      |:||.    .|:.:..|.|::|.|...:|
  Fly   227 TGVTVNALNPG-IADTEIARNMIFFQTKFAQYVVETILRPLLWAVMKTPKNGAQTTLYAALDPDL 290

  Fly   364 TGLSGLYFNNCFFCEPSKLSKSAALQQQLWKLSE 397
            ..:||.||::|.....:..:....:.|.||..||
  Fly   291 ERVSGQYFSDCALAPVAPAALDDQMAQWLWAQSE 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	98/291 (34%)
CG30495	NP_001260785.1	Rossmann-fold NAD(P)(+)-binding proteins	45..323	CDD:473865	96/288 (33%)